The Presence of Substrate Warrants Oxygen Access Tunnels Toward the Catalytic Site of Lipoxygenases Article Swipe

View

Karolina Mikulska‐Ruminska , Thiliban Manivarma , Wiesław Nowak , Yulia Y. Tyurina , Vladimir A. Tyurin , Hülya Bayır , Valerian E. Kagan ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.2139/ssrn.5060100

Related Topics

Concepts

Substrate (aquarium) Catalysis Chemistry Oxygen Business Biochemistry Biology Organic chemistry Ecology

Metadata

Type: preprint
Language: en
Landing Page: https://doi.org/10.2139/ssrn.5060100
OA Status: green
References: 56
Related Works: 10
OpenAlex ID: https://openalex.org/W4405432395

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W4405432395

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.2139/ssrn.5060100

Digital Object Identifier
Title: The Presence of Substrate Warrants Oxygen Access Tunnels Toward the Catalytic Site of Lipoxygenases

Work title
Type: preprint

OpenAlex work type
Language: en

Primary language
Publication year: 2024

Year of publication
Publication date: 2024-01-01

Full publication date if available
Authors: Karolina Mikulska‐Ruminska, Thiliban Manivarma, Wiesław Nowak, Yulia Y. Tyurina, Vladimir A. Tyurin, Hülya Bayır, Valerian E. Kagan

List of authors in order
Landing page: https://doi.org/10.2139/ssrn.5060100

Publisher landing page
Open access: Yes

Whether a free full text is available
OA status: green

Open access status per OpenAlex
OA URL: https://doi.org/10.2139/ssrn.5060100

Direct OA link when available
Concepts: Substrate (aquarium), Catalysis, Chemistry, Oxygen, Business, Biochemistry, Biology, Organic chemistry, Ecology

Top concepts (fields/topics) attached by OpenAlex
Cited by: 0

Total citation count in OpenAlex
References (count): 56

Number of works referenced by this work
Related works (count): 10

Other works algorithmically related by OpenAlex

Full payload

id	https://openalex.org/W4405432395
doi	https://doi.org/10.2139/ssrn.5060100
ids.doi	https://doi.org/10.2139/ssrn.5060100
ids.openalex	https://openalex.org/W4405432395
fwci
type	preprint
title	The Presence of Substrate Warrants Oxygen Access Tunnels Toward the Catalytic Site of Lipoxygenases
biblio.issue
biblio.volume
biblio.last_page
biblio.first_page
topics[0].id	https://openalex.org/T10252
topics[0].field.id	https://openalex.org/fields/27
topics[0].field.display_name	Medicine
topics[0].score	0.9567000269889832
topics[0].domain.id	https://openalex.org/domains/4
topics[0].domain.display_name	Health Sciences
topics[0].subfield.id	https://openalex.org/subfields/2736
topics[0].subfield.display_name	Pharmacology
topics[0].display_name	Microbial Natural Products and Biosynthesis
topics[1].id	https://openalex.org/T13160
topics[1].field.id	https://openalex.org/fields/16
topics[1].field.display_name	Chemistry
topics[1].score	0.9441999793052673
topics[1].domain.id	https://openalex.org/domains/3
topics[1].domain.display_name	Physical Sciences
topics[1].subfield.id	https://openalex.org/subfields/1605
topics[1].subfield.display_name	Organic Chemistry
topics[1].display_name	Synthesis and Biological Evaluation
topics[2].id	https://openalex.org/T11440
topics[2].field.id	https://openalex.org/fields/16
topics[2].field.display_name	Chemistry
topics[2].score	0.9301000237464905
topics[2].domain.id	https://openalex.org/domains/3
topics[2].domain.display_name	Physical Sciences
topics[2].subfield.id	https://openalex.org/subfields/1605
topics[2].subfield.display_name	Organic Chemistry
topics[2].display_name	Click Chemistry and Applications
is_xpac	False
apc_list
apc_paid
concepts[0].id	https://openalex.org/C2777289219
concepts[0].level	2
concepts[0].score	0.670510470867157
concepts[0].wikidata	https://www.wikidata.org/wiki/Q7632154
concepts[0].display_name	Substrate (aquarium)
concepts[1].id	https://openalex.org/C161790260
concepts[1].level	2
concepts[1].score	0.564365565776825
concepts[1].wikidata	https://www.wikidata.org/wiki/Q82264
concepts[1].display_name	Catalysis
concepts[2].id	https://openalex.org/C185592680
concepts[2].level	0
concepts[2].score	0.5359509587287903
concepts[2].wikidata	https://www.wikidata.org/wiki/Q2329
concepts[2].display_name	Chemistry
concepts[3].id	https://openalex.org/C540031477
concepts[3].level	2
concepts[3].score	0.5193710923194885
concepts[3].wikidata	https://www.wikidata.org/wiki/Q629
concepts[3].display_name	Oxygen
concepts[4].id	https://openalex.org/C144133560
concepts[4].level	0
concepts[4].score	0.35203254222869873
concepts[4].wikidata	https://www.wikidata.org/wiki/Q4830453
concepts[4].display_name	Business
concepts[5].id	https://openalex.org/C55493867
concepts[5].level	1
concepts[5].score	0.2503090500831604
concepts[5].wikidata	https://www.wikidata.org/wiki/Q7094
concepts[5].display_name	Biochemistry
concepts[6].id	https://openalex.org/C86803240
concepts[6].level	0
concepts[6].score	0.1193021833896637
concepts[6].wikidata	https://www.wikidata.org/wiki/Q420
concepts[6].display_name	Biology
concepts[7].id	https://openalex.org/C178790620
concepts[7].level	1
concepts[7].score	0.11739462614059448
concepts[7].wikidata	https://www.wikidata.org/wiki/Q11351
concepts[7].display_name	Organic chemistry
concepts[8].id	https://openalex.org/C18903297
concepts[8].level	1
concepts[8].score	0.066089928150177
concepts[8].wikidata	https://www.wikidata.org/wiki/Q7150
concepts[8].display_name	Ecology
keywords[0].id	https://openalex.org/keywords/substrate
keywords[0].score	0.670510470867157
keywords[0].display_name	Substrate (aquarium)
keywords[1].id	https://openalex.org/keywords/catalysis
keywords[1].score	0.564365565776825
keywords[1].display_name	Catalysis
keywords[2].id	https://openalex.org/keywords/chemistry
keywords[2].score	0.5359509587287903
keywords[2].display_name	Chemistry
keywords[3].id	https://openalex.org/keywords/oxygen
keywords[3].score	0.5193710923194885
keywords[3].display_name	Oxygen
keywords[4].id	https://openalex.org/keywords/business
keywords[4].score	0.35203254222869873
keywords[4].display_name	Business
keywords[5].id	https://openalex.org/keywords/biochemistry
keywords[5].score	0.2503090500831604
keywords[5].display_name	Biochemistry
keywords[6].id	https://openalex.org/keywords/biology
keywords[6].score	0.1193021833896637
keywords[6].display_name	Biology
keywords[7].id	https://openalex.org/keywords/organic-chemistry
keywords[7].score	0.11739462614059448
keywords[7].display_name	Organic chemistry
keywords[8].id	https://openalex.org/keywords/ecology
keywords[8].score	0.066089928150177
keywords[8].display_name	Ecology
language	en
locations[0].id	doi:10.2139/ssrn.5060100
locations[0].is_oa	True
locations[0].source.id	https://openalex.org/S4210172589
locations[0].source.issn	1556-5068
locations[0].source.type	repository
locations[0].source.is_oa	True
locations[0].source.issn_l	1556-5068
locations[0].source.is_core	False
locations[0].source.is_in_doaj	False
locations[0].source.display_name	SSRN Electronic Journal
locations[0].source.host_organization	https://openalex.org/I1318003438
locations[0].source.host_organization_name	RELX Group (Netherlands)
locations[0].source.host_organization_lineage	https://openalex.org/I1318003438
locations[0].license
locations[0].pdf_url
locations[0].version	acceptedVersion
locations[0].raw_type	posted-content
locations[0].license_id
locations[0].is_accepted	True
locations[0].is_published	False
locations[0].raw_source_name
locations[0].landing_page_url	https://doi.org/10.2139/ssrn.5060100
indexed_in	crossref
authorships[0].author.id	https://openalex.org/A5040279016
authorships[0].author.orcid	https://orcid.org/0000-0001-7227-5503
authorships[0].author.display_name	Karolina Mikulska‐Ruminska
authorships[0].author_position	first
authorships[0].raw_author_name	Karolina Mikulska-Ruminska
authorships[0].is_corresponding	False
authorships[1].author.id	https://openalex.org/A5047160138
authorships[1].author.orcid	https://orcid.org/0000-0002-4092-9119
authorships[1].author.display_name	Thiliban Manivarma
authorships[1].author_position	middle
authorships[1].raw_author_name	Thiliban Manivarma
authorships[1].is_corresponding	False
authorships[2].author.id	https://openalex.org/A5054152314
authorships[2].author.orcid	https://orcid.org/0000-0003-2584-1327
authorships[2].author.display_name	Wiesław Nowak
authorships[2].author_position	middle
authorships[2].raw_author_name	Wieslaw Nowak
authorships[2].is_corresponding	False
authorships[3].author.id	https://openalex.org/A5055133721
authorships[3].author.orcid	https://orcid.org/0000-0003-0287-2091
authorships[3].author.display_name	Yulia Y. Tyurina
authorships[3].author_position	middle
authorships[3].raw_author_name	Yulia Y. Tyurina
authorships[3].is_corresponding	False
authorships[4].author.id	https://openalex.org/A5040760802
authorships[4].author.orcid	https://orcid.org/0000-0002-3474-1697
authorships[4].author.display_name	Vladimir A. Tyurin
authorships[4].author_position	middle
authorships[4].raw_author_name	Vladimir A. Tyurin
authorships[4].is_corresponding	False
authorships[5].author.id	https://openalex.org/A5061593498
authorships[5].author.orcid	https://orcid.org/0000-0003-2361-4120
authorships[5].author.display_name	Hülya Bayır
authorships[5].author_position	middle
authorships[5].raw_author_name	Hülya Bayır
authorships[5].is_corresponding	False
authorships[6].author.id	https://openalex.org/A5049450190
authorships[6].author.orcid	https://orcid.org/0000-0002-7245-1885
authorships[6].author.display_name	Valerian E. Kagan
authorships[6].author_position	last
authorships[6].raw_author_name	Valerian Kagan
authorships[6].is_corresponding	False
has_content.pdf	False
has_content.grobid_xml	False
is_paratext	False
open_access.is_oa	True
open_access.oa_url	https://doi.org/10.2139/ssrn.5060100
open_access.oa_status	green
open_access.any_repository_has_fulltext	False
created_date	2025-10-10T00:00:00
display_name	The Presence of Substrate Warrants Oxygen Access Tunnels Toward the Catalytic Site of Lipoxygenases
has_fulltext	False
is_retracted	False
updated_date	2025-11-06T03:46:38.306776
primary_topic.id	https://openalex.org/T10252
primary_topic.field.id	https://openalex.org/fields/27
primary_topic.field.display_name	Medicine
primary_topic.score	0.9567000269889832
primary_topic.domain.id	https://openalex.org/domains/4
primary_topic.domain.display_name	Health Sciences
primary_topic.subfield.id	https://openalex.org/subfields/2736
primary_topic.subfield.display_name	Pharmacology
primary_topic.display_name	Microbial Natural Products and Biosynthesis
related_works	https://openalex.org/W4387497383, https://openalex.org/W2948807893, https://openalex.org/W2899084033, https://openalex.org/W2778153218, https://openalex.org/W2748952813, https://openalex.org/W1531601525, https://openalex.org/W4391375266, https://openalex.org/W2078814861, https://openalex.org/W2527526854, https://openalex.org/W1976181487
cited_by_count	0
locations_count	1
best_oa_location.id	doi:10.2139/ssrn.5060100
best_oa_location.is_oa	True
best_oa_location.source.id	https://openalex.org/S4210172589
best_oa_location.source.issn	1556-5068
best_oa_location.source.type	repository
best_oa_location.source.is_oa	True
best_oa_location.source.issn_l	1556-5068
best_oa_location.source.is_core	False
best_oa_location.source.is_in_doaj	False
best_oa_location.source.display_name	SSRN Electronic Journal
best_oa_location.source.host_organization	https://openalex.org/I1318003438
best_oa_location.source.host_organization_name	RELX Group (Netherlands)
best_oa_location.source.host_organization_lineage	https://openalex.org/I1318003438
best_oa_location.license
best_oa_location.pdf_url
best_oa_location.version	acceptedVersion
best_oa_location.raw_type	posted-content
best_oa_location.license_id
best_oa_location.is_accepted	True
best_oa_location.is_published	False
best_oa_location.raw_source_name
best_oa_location.landing_page_url	https://doi.org/10.2139/ssrn.5060100
primary_location.id	doi:10.2139/ssrn.5060100
primary_location.is_oa	True
primary_location.source.id	https://openalex.org/S4210172589
primary_location.source.issn	1556-5068
primary_location.source.type	repository
primary_location.source.is_oa	True
primary_location.source.issn_l	1556-5068
primary_location.source.is_core	False
primary_location.source.is_in_doaj	False
primary_location.source.display_name	SSRN Electronic Journal
primary_location.source.host_organization	https://openalex.org/I1318003438
primary_location.source.host_organization_name	RELX Group (Netherlands)
primary_location.source.host_organization_lineage	https://openalex.org/I1318003438
primary_location.license
primary_location.pdf_url
primary_location.version	acceptedVersion
primary_location.raw_type	posted-content
primary_location.license_id
primary_location.is_accepted	True
primary_location.is_published	False
primary_location.raw_source_name
primary_location.landing_page_url	https://doi.org/10.2139/ssrn.5060100
publication_date	2024-01-01
publication_year	2024
referenced_works	https://openalex.org/W2804102163, https://openalex.org/W2204004844, https://openalex.org/W2550324626, https://openalex.org/W2035898183, https://openalex.org/W4390947266, https://openalex.org/W4308723853, https://openalex.org/W4392917639, https://openalex.org/W4386529507, https://openalex.org/W3093193545, https://openalex.org/W3006341053, https://openalex.org/W2905449420, https://openalex.org/W3163142996, https://openalex.org/W1997183854, https://openalex.org/W2606355783, https://openalex.org/W4220910464, https://openalex.org/W3016365053, https://openalex.org/W2786707817, https://openalex.org/W2592029987, https://openalex.org/W2098509825, https://openalex.org/W4385446443, https://openalex.org/W2990717241, https://openalex.org/W1974332498, https://openalex.org/W2155687740, https://openalex.org/W2081553848, https://openalex.org/W2894095027, https://openalex.org/W2043952276, https://openalex.org/W4385262352, https://openalex.org/W2169076235, https://openalex.org/W2342569995, https://openalex.org/W2970854154, https://openalex.org/W2799633991, https://openalex.org/W4399319258, https://openalex.org/W1988589639, https://openalex.org/W2026581440, https://openalex.org/W2029582401, https://openalex.org/W1976161355, https://openalex.org/W1986743126, https://openalex.org/W1597844740, https://openalex.org/W2009156058, https://openalex.org/W2043176868, https://openalex.org/W2026911129, https://openalex.org/W2913355937, https://openalex.org/W2140000393, https://openalex.org/W6773858992, https://openalex.org/W2892710900, https://openalex.org/W2150981663, https://openalex.org/W2206954826, https://openalex.org/W2140831051, https://openalex.org/W2120772351, https://openalex.org/W2123681603, https://openalex.org/W2168526937, https://openalex.org/W2759112714, https://openalex.org/W2137015675, https://openalex.org/W3023726965, https://openalex.org/W3102092593, https://openalex.org/W3003960907
referenced_works_count	56
abstract_inverted_index
cited_by_percentile_year
countries_distinct_count	0
institutions_distinct_count	7
citation_normalized_percentile.value	0.26615615
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False