The relationship between programmed cell death and vascular calcification Article Swipe
Jie Zheng
,
Zhiping Lin
,
Xiaolin Zhong
,
Jianghua Liu
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3389/fcvm.2025.1549857
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3389/fcvm.2025.1549857
Vascular calcification (VC) is a pathological condition closely associated with a range of cardiovascular diseases, including atherosclerosis (AS), hypertension, vascular injury, and diabetic angiopathy. Programmed cell death, encompassing apoptosis, autophagy, pyroptosis and ferroptosis, plays a pivotal role in the progression of VC. These cellular processes are intricately regulated by multiple signaling pathways, such as the Wnt/β-catenin and NF-κB pathways, among others. A deeper understanding of the roles and underlying mechanisms of programmed cell death in VC could offer valuable insights for the development of innovative therapeutic strategies targeting cardiovascular diseases.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.3389/fcvm.2025.1549857
- https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1549857/pdf
- OA Status
- gold
- References
- 84
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4412173359
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4412173359Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3389/fcvm.2025.1549857Digital Object Identifier
- Title
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The relationship between programmed cell death and vascular calcificationWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-07-10Full publication date if available
- Authors
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Jie Zheng, Zhiping Lin, Xiaolin Zhong, Jianghua LiuList of authors in order
- Landing page
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https://doi.org/10.3389/fcvm.2025.1549857Publisher landing page
- PDF URL
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https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1549857/pdfDirect link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1549857/pdfDirect OA link when available
- Concepts
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Pyroptosis, Autophagy, Programmed cell death, Apoptosis, Necroptosis, Cause of death, Medicine, Wnt signaling pathway, Pathological, Calcification, Signal transduction, Cancer research, Cell biology, Neuroscience, Biology, Disease, Pathology, BiochemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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84Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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