The Risk‐Reducing Effect of Aspirin in Lynch Syndrome Carriers: Development and Evaluation of an Educational Leaflet Article Swipe
Rajneesh Kaur
,
Cassandra McDonald
,
Bettina Meiser
,
Finlay Macrae
,
Sian K. Smith
,
Yoon Jung Kang
,
Michael Caruana
,
Gillian Mitchell
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1002/ggn2.202100046
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1002/ggn2.202100046
Carriers of germline mutations in genes associated with Lynch syndrome are at increased risk for colorectal, endometrial, ovarian, and other cancers. There is evidence that daily consumption of aspirin may reduce cancer risk in these individuals. There is a need for educational resources to inform carriers of the risk‐reducing effects of aspirin or to support decision‐making. An educational leaflet describing the risks and benefits of using aspirin as risk‐reducing medicine in carriers of Lynch‐syndrome‐related mutations is developed and pilot tested in 2017. Carriers are ascertained through a familial cancer clinic and surveyed using a mailed, self‐administered questionnaire. The leaflet is highly rated for its content, clarity, length, relevance, and visual appeal by more than 70% of the participants. Most participants (91%) report “a lot” or “quite a bit” of improvement in perceived understanding in knowledge about who might benefit from taking aspirin, its benefits, how long to take it, the reduction in bowel cancer risk, and the optimal dosage. A few (14%) participants seek more information on the dosage of aspirin. This leaflet will be useful as an aid to facilitate discussion between patients and their health care professionals about the use of aspirin as a risk‐reducing medication.
Related Topics
Concepts
Aspirin
Medicine
Lynch syndrome
Colorectal cancer
Oncology
Cancer
Family medicine
Internal medicine
DNA mismatch repair
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1002/ggn2.202100046
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ggn2.202100046
- OA Status
- gold
- Cited By
- 2
- References
- 35
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4220671017
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4220671017Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1002/ggn2.202100046Digital Object Identifier
- Title
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The Risk‐Reducing Effect of Aspirin in Lynch Syndrome Carriers: Development and Evaluation of an Educational LeafletWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-03-07Full publication date if available
- Authors
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Rajneesh Kaur, Cassandra McDonald, Bettina Meiser, Finlay Macrae, Sian K. Smith, Yoon Jung Kang, Michael Caruana, Gillian MitchellList of authors in order
- Landing page
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https://doi.org/10.1002/ggn2.202100046Publisher landing page
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ggn2.202100046Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ggn2.202100046Direct OA link when available
- Concepts
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Aspirin, Medicine, Lynch syndrome, Colorectal cancer, Oncology, Cancer, Family medicine, Internal medicine, DNA mismatch repairTop concepts (fields/topics) attached by OpenAlex
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2Total citation count in OpenAlex
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2024: 1, 2023: 1Per-year citation counts (last 5 years)
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35Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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