The role of long non-coding RNA in hepatocellular carcinoma Article Swipe
Weizheng Liang
,
Yan Zhao
,
Qingxue Meng
,
Wenjie Jiang
,
Shoulong Deng
,
Jun Xue
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.18632/aging.205523
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.18632/aging.205523
Hepatocellular carcinoma (HCC) is a prevalent liver malignancy with complex etiology and generally poor prognosis. Recently, long non-coding RNAs (lncRNAs), non-protein-coding RNA molecules exceeding 200 nucleotides, have emerged as pivotal players in HCC, influencing its initiation, progression, invasion, and metastasis. These lncRNAs modulate gene expression at epigenetic, transcriptional, and post-transcriptional levels, actively participating in the pathological and physiological processes of HCC. Understanding the intricate relationship between lncRNAs and HCC is important for improving prognosis and reducing mortality. This review summarizes advancements in elucidating the role of lncRNAs in HCC pathogenesis.
Related Topics
Concepts
Hepatocellular carcinoma
Epigenetics
Long non-coding RNA
Malignancy
Biology
Metastasis
Gene
Pathogenesis
RNA
Cancer research
Non-coding RNA
Bioinformatics
Genetics
Cancer
Immunology
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.18632/aging.205523
- https://www.aging-us.com/article/205523/pdf
- OA Status
- hybrid
- Cited By
- 21
- References
- 142
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4391637169
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4391637169Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.18632/aging.205523Digital Object Identifier
- Title
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The role of long non-coding RNA in hepatocellular carcinomaWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-02-08Full publication date if available
- Authors
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Weizheng Liang, Yan Zhao, Qingxue Meng, Wenjie Jiang, Shoulong Deng, Jun XueList of authors in order
- Landing page
-
https://doi.org/10.18632/aging.205523Publisher landing page
- PDF URL
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https://www.aging-us.com/article/205523/pdfDirect link to full text PDF
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
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https://www.aging-us.com/article/205523/pdfDirect OA link when available
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Hepatocellular carcinoma, Epigenetics, Long non-coding RNA, Malignancy, Biology, Metastasis, Gene, Pathogenesis, RNA, Cancer research, Non-coding RNA, Bioinformatics, Genetics, Cancer, ImmunologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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21Total citation count in OpenAlex
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2025: 14, 2024: 7Per-year citation counts (last 5 years)
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142Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.8299999833106995 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.98155218 |
| citation_normalized_percentile.is_in_top_1_percent | True |
| citation_normalized_percentile.is_in_top_10_percent | True |