The Role of Malondialdehyde (MDA) and Ferric Reducing Antioxidant Power (FRAP) in Patients with Hypertension Article Swipe
YOU?
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· 2023
· Open Access
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· DOI: https://doi.org/10.21705/mcbs.v7i2.288
Oxidative stress contributes to the pathogenesis of hypertension and studies have shown that hypertension is associated with an increase in oxidative stress. Reactive oxygen species (ROS) lead to hypertension and antioxidants may be beneficial for its prevention. The main cause of oxidative stress in hypertension is endothelial dysfunction due to the malfunctions in the vasodilator systems, specifically the molecular mechanism of ROS and nitric oxide (NO). The level of malondialdehyde (MDA), a biomarker of lipid peroxidation and oxidative stress, is found to be higher in hypertension patients. Total antioxidant capacity (TAC), which has a strong relationship with blood pressure, is determined through the ferric reducing antioxidant power (FRAP). The aim of the review article is to elucidate the role of MDA and FRAP in hypertension.Keywords: oxidative stress, hypertension, blood pressure, oxidative damage, malondialdehyde, FRAP
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.21705/mcbs.v7i2.288
- https://cellbiopharm.com/ojs/index.php/MCBS/article/download/288/117
- OA Status
- diamond
- Cited By
- 3
- References
- 83
- Related Works
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- OpenAlex ID
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Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4384695327Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.21705/mcbs.v7i2.288Digital Object Identifier
- Title
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The Role of Malondialdehyde (MDA) and Ferric Reducing Antioxidant Power (FRAP) in Patients with HypertensionWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-07-18Full publication date if available
- Authors
-
Rohsan Alam, Haseeb Ahsan, Saba KhanList of authors in order
- Landing page
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https://doi.org/10.21705/mcbs.v7i2.288Publisher landing page
- PDF URL
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https://cellbiopharm.com/ojs/index.php/MCBS/article/download/288/117Direct link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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diamondOpen access status per OpenAlex
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https://cellbiopharm.com/ojs/index.php/MCBS/article/download/288/117Direct OA link when available
- Concepts
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Malondialdehyde, Oxidative stress, Reactive oxygen species, Lipid peroxidation, Antioxidant, Ferric reducing ability of plasma, Nitric oxide, Internal medicine, Chemistry, Endothelial dysfunction, Medicine, Endocrinology, Biochemistry, Antioxidant capacityTop concepts (fields/topics) attached by OpenAlex
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3Total citation count in OpenAlex
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2025: 1, 2024: 1, 2023: 1Per-year citation counts (last 5 years)
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83Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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