The Role of Placental MFF-Mediated Mitochondrial Fission in Gestational Diabetes Mellitus Article Swipe
Related Concepts
Gestational diabetes
Mitochondrial fission
Fission
Medicine
Diabetes mellitus
Internal medicine
Endocrinology
Obstetrics
Andrology
Mitochondrion
Biology
Pregnancy
Gestation
Cell biology
Physics
Genetics
Nuclear physics
Neutron
Lijie Wei
,
Caiyun Fang
,
Yi Jiang
,
Huiting Zhang
,
Peng Gao
,
Xuan Zhou
,
Shenglan Zhu
,
Yuanyuan Du
,
Rui Su
,
Lili Guo
,
Mengzhou He
,
Shaoshuai Wang
,
Ling Feng
,
Shuang Yu
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.2147/dmso.s484002
· OA: W4407794133
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.2147/dmso.s484002
· OA: W4407794133
Our study demonstrates that MFF-mediated mitochondrial fission inhibits insulin sensitivity and upregulates glucose transport in GDM, which is related to offspring exposure to a hyperglycemic intrauterine environment. These results provide a novel therapeutic target for addressing GDM that may mitigate unfavorable pregnancy outcomes.
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