The role of prognostic nutritional index in predicting amputation in patients with lower extremity peripheral artery disease Article Swipe
Hilal Erken Pamukçu
,
Hamza Sunman
,
Alperen Taş
,
Mert Aker
,
Haluk Furkan Şahan
,
Sadık Açıkel
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.34172/jcvtr.2021.02
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.34172/jcvtr.2021.02
Introduction: Lower-extremity peripheral artery disease (PAD) can lead to a wide spectrum of symptoms that can progress from claudication to amputation. The prognostic nutritional index (PNI), which is calculated using the levels of albumin and lymphocyte, is an accepted indicator of immunological and nutritional status. In this study, the association between nutritional status determined using the PNI, and extremity amputation in patients with lower-extremity PAD was investigated. Methods: Lower-extremity PAD patients who had been admitted to the cardiology clinic of the Dışkapı Yıldırım Beyazıt Training & Research Hospital with stage 2b or higher claudication, and who were technically unsuitable for revascularization or underwent unsuccessful revascularization procedure were enrolled in this retrospective study. Patients were grouped according to whether or not limb amputation had been performed previously. Potential factors were tested to detect independent predictors for amputation with logistic regression analysis. Results: A study group was formed with 266 peripheral artery patients. The amputated group (39 patients) had a higher number of hypertensive (76.9% vs 57.7%; P = 0.032) and diabetic (92.3% vs 54.2%; P <0.001) patients than those in the non-amputated group (227 patients). The median PNI value of the amputated group was lower than that of the non-amputated group (31.8 vs 39.4; P <0.001). Multivariate logistic regression showed that the PNI (OR: 0.905, 95% CI: 0.859 – 0.954; P <0.001) was independently related with amputation. Conclusion: Immune-nutritional status based on PNI was independently associated with limb amputation in patients with lower-extremity PAD.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.34172/jcvtr.2021.02
- https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-13-43.pdf
- OA Status
- diamond
- Cited By
- 15
- References
- 31
- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3124889186Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.34172/jcvtr.2021.02Digital Object Identifier
- Title
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The role of prognostic nutritional index in predicting amputation in patients with lower extremity peripheral artery diseaseWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
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2021-01-13Full publication date if available
- Authors
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Hilal Erken Pamukçu, Hamza Sunman, Alperen Taş, Mert Aker, Haluk Furkan Şahan, Sadık AçıkelList of authors in order
- Landing page
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https://doi.org/10.34172/jcvtr.2021.02Publisher landing page
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https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-13-43.pdfDirect link to full text PDF
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-13-43.pdfDirect OA link when available
- Concepts
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Medicine, Amputation, Logistic regression, Claudication, Peripheral, Internal medicine, Arterial disease, Retrospective cohort study, Revascularization, Surgery, Cardiology, Vascular disease, Myocardial infarctionTop concepts (fields/topics) attached by OpenAlex
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15Total citation count in OpenAlex
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2025: 2, 2024: 3, 2023: 5, 2022: 4, 2021: 1Per-year citation counts (last 5 years)
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31Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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