The Silent Threat of BPA: Its Pervasive Presence and Impact on Reproductive Health Article Swipe
Sanman Samova
,
Hetal Doctor
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1177/11786302251330774
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1177/11786302251330774
Bisphenol A (BPA) is a synthetic organic compound commonly utilized in the manufacturing of polycarbonate plastics and epoxy resins. Its widespread presence in everyday items, including water bottles, food containers, and thermal paper, has raised considerable health concerns due to its potential as an endocrine disruptor. BPA has the ability to mimic estrogen and bind to estrogen receptors, which can lead to disruptions in hormonal signaling pathways. This interference poses risks to reproductive health, especially among younger individuals, as it may result in irregular menstrual cycles, ovulation issues, and compromised spermatogenesis. Research indicates that BPA exposure can adversely affect ovarian function, diminish sperm quality, and induce oxidative stress and inflammation, further compromising fertility. The potential for BPA to cause long-term health effects through epigenetic modifications, alongside its prevalence in food contact materials, underscores the urgent need for strategies to minimize exposure. Recommended approaches include the use of BPA-free products, choosing fresh foods over canned items, and advocating for stricter regulations. A deeper understanding of the mechanisms underlying BPA’s reproductive toxicity is essential for developing effective interventions. Additionally, research is needed to address critical gaps in knowledge regarding the cumulative effects of low-dose exposure, transgenerational impacts, and the specific effects on male fertility. Investigating epigenetic mechanisms, variability in susceptibility, and the safety of BPA alternatives is paramount. Furthermore, exploring effective interventions, increasing public awareness, and implementing regulatory measures are crucial steps in mitigating BPA’s adverse effects on reproductive health.
Related Topics
Concepts
Benzhydryl compounds
Reproductive health
Endocrine disruptor
Psychological intervention
Adverse effect
Medicine
Fertility
Environmental health
Physiology
Bisphenol A
Endocrine system
Hormone
Pharmacology
Population
Endocrinology
Chemistry
Psychiatry
Epoxy
Organic chemistry
Metadata
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- review
- Language
- en
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- https://doi.org/10.1177/11786302251330774
- OA Status
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- References
- 42
- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
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https://openalex.org/W4411747300Canonical identifier for this work in OpenAlex
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https://doi.org/10.1177/11786302251330774Digital Object Identifier
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The Silent Threat of BPA: Its Pervasive Presence and Impact on Reproductive HealthWork title
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reviewOpenAlex work type
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enPrimary language
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2025Year of publication
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2025-06-01Full publication date if available
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Sanman Samova, Hetal DoctorList of authors in order
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https://doi.org/10.1177/11786302251330774Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.1177/11786302251330774Direct OA link when available
- Concepts
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Benzhydryl compounds, Reproductive health, Endocrine disruptor, Psychological intervention, Adverse effect, Medicine, Fertility, Environmental health, Physiology, Bisphenol A, Endocrine system, Hormone, Pharmacology, Population, Endocrinology, Chemistry, Psychiatry, Epoxy, Organic chemistryTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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| referenced_works | https://openalex.org/W2128799803, https://openalex.org/W1970760886, https://openalex.org/W1976755375, https://openalex.org/W2135854123, https://openalex.org/W2162615578, https://openalex.org/W2121319979, https://openalex.org/W2025811822, https://openalex.org/W2067753015, https://openalex.org/W2127567198, https://openalex.org/W2022118247, https://openalex.org/W2133734192, https://openalex.org/W2114729638, https://openalex.org/W2136799713, https://openalex.org/W1967211742, https://openalex.org/W1970358298, https://openalex.org/W2100723447, https://openalex.org/W2044641854, https://openalex.org/W2049240688, https://openalex.org/W2051496113, https://openalex.org/W2028071281, https://openalex.org/W2037278965, https://openalex.org/W2074271561, https://openalex.org/W2046176216, https://openalex.org/W1991626426, https://openalex.org/W2104445964, https://openalex.org/W2006104250, https://openalex.org/W2754268594, https://openalex.org/W2981438781, https://openalex.org/W2956945510, https://openalex.org/W1998568000, https://openalex.org/W2026430846, https://openalex.org/W2161393867, https://openalex.org/W3037486043, https://openalex.org/W2982356922, https://openalex.org/W2151355547, https://openalex.org/W2158322830, https://openalex.org/W2121036241, https://openalex.org/W3092873518, https://openalex.org/W2770533293, https://openalex.org/W2836174168, https://openalex.org/W2799621299, https://openalex.org/W2509238246 |
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