The therapeutic benefits of NSAIDs and physical therapy in knee osteoarthritis Article Swipe
George Ovidiu Cioroianu
,
Alesandra Florescu
,
Cristiana Eugenia Simionescu
,
Teodor Nicuşor Sas
,
Daniela Tarniţă
,
Otilia Constantina Rogoveanu
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.47162/rjme.65.2.08
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.47162/rjme.65.2.08
Introduction: Osteoarthritis (OA) has been established as a progressive wear and tear disease of the synovial joints, which also involves a certain degree of inflammation. Considering there is no disease modifying medication available at the moment, the current guidelines focus on the symptomatic treatment of the affection. Our study aimed to evaluate the therapeutic advantages of the synergistic use of non-steroidal anti-inflammatory drugs (NSAIDs) and physical therapy in the treatment of knee osteoarthritis (KOA). Patients, Materials and Methods: The study comprised 46 individuals who were diagnosed with KOA and were admitted to the Department of Physical Medicine and Rehabilitation at the Emergency Clinical County Hospital of Craiova, Romania, between January 2021 and April 2022. All the participants received the same combination of pharmacological (Diclofenac 150 mg/day, no more than 10 days/month as needed) and non-pharmacological treatment (a 24-week plan of physical therapy). Results: The patient group exhibited a statistically significant reduction in both the average Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index (p=0.0142) and the average Visual Analog Scale (VAS) (p=0.0023). Additionally, there was a statistically significant increase in both the average Knee Outcome Survey–Activities of Daily Living (KOS–ADL) (p=0.0128) and the average Oxford Knee Score (OKS) (p=0.0023). The study found a significant positive correlation between higher VAS ratings and cholesterol levels (p=0.0092), but no significant correlation between VAS scores and triglyceride levels (p=0.0986). Patients were evaluated for a further 24 weeks beyond the conclusion of the research to see if surgical intervention was necessary during this time. Conclusions: Our investigation tracked the WOMAC, VAS, KOS–ADL, and OKS measurements in a cohort of patients with KOA. The results demonstrate that the utilization of NSAIDs in conjunction with physical therapy effectively alleviates pain and enhances joint functionality.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.47162/rjme.65.2.08
- https://rjme.ro/RJME/resources/files/650224217224.pdf
- OA Status
- diamond
- Cited By
- 6
- References
- 41
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4400800764
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4400800764Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.47162/rjme.65.2.08Digital Object Identifier
- Title
-
The therapeutic benefits of NSAIDs and physical therapy in knee osteoarthritisWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-07-15Full publication date if available
- Authors
-
George Ovidiu Cioroianu, Alesandra Florescu, Cristiana Eugenia Simionescu, Teodor Nicuşor Sas, Daniela Tarniţă, Otilia Constantina RogoveanuList of authors in order
- Landing page
-
https://doi.org/10.47162/rjme.65.2.08Publisher landing page
- PDF URL
-
https://rjme.ro/RJME/resources/files/650224217224.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://rjme.ro/RJME/resources/files/650224217224.pdfDirect OA link when available
- Concepts
-
Osteoarthritis, Medicine, Disease, Physical therapy, Knee Joint, Therapeutic approach, Internal medicine, Surgery, Alternative medicine, PathologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
6Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 5, 2024: 1Per-year citation counts (last 5 years)
- References (count)
-
41Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4400800764 |
|---|---|
| doi | https://doi.org/10.47162/rjme.65.2.08 |
| ids.doi | https://doi.org/10.47162/rjme.65.2.08 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/39020536 |
| ids.openalex | https://openalex.org/W4400800764 |
| fwci | 6.29674943 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | Q000628 |
| mesh[1].descriptor_ui | D020370 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | therapy |
| mesh[1].descriptor_name | Osteoarthritis, Knee |
| mesh[2].qualifier_ui | Q000188 |
| mesh[2].descriptor_ui | D020370 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | drug therapy |
| mesh[2].descriptor_name | Osteoarthritis, Knee |
| mesh[3].qualifier_ui | Q000627 |
| mesh[3].descriptor_ui | D000894 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | therapeutic use |
| mesh[3].descriptor_name | Anti-Inflammatory Agents, Non-Steroidal |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D005260 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Female |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D008297 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Male |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D008875 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Middle Aged |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D026741 |
| mesh[7].is_major_topic | True |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Physical Therapy Modalities |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D000368 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Aged |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D006801 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Humans |
| mesh[10].qualifier_ui | Q000628 |
| mesh[10].descriptor_ui | D020370 |
| mesh[10].is_major_topic | True |
| mesh[10].qualifier_name | therapy |
| mesh[10].descriptor_name | Osteoarthritis, Knee |
| mesh[11].qualifier_ui | Q000188 |
| mesh[11].descriptor_ui | D020370 |
| mesh[11].is_major_topic | True |
| mesh[11].qualifier_name | drug therapy |
| mesh[11].descriptor_name | Osteoarthritis, Knee |
| mesh[12].qualifier_ui | Q000627 |
| mesh[12].descriptor_ui | D000894 |
| mesh[12].is_major_topic | True |
| mesh[12].qualifier_name | therapeutic use |
| mesh[12].descriptor_name | Anti-Inflammatory Agents, Non-Steroidal |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D005260 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Female |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D008297 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Male |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D008875 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Middle Aged |
| mesh[16].qualifier_ui | |
| mesh[16].descriptor_ui | D026741 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | |
| mesh[16].descriptor_name | Physical Therapy Modalities |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D000368 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Aged |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D006801 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Humans |
| mesh[19].qualifier_ui | Q000628 |
| mesh[19].descriptor_ui | D020370 |
| mesh[19].is_major_topic | True |
| mesh[19].qualifier_name | therapy |
| mesh[19].descriptor_name | Osteoarthritis, Knee |
| mesh[20].qualifier_ui | Q000188 |
| mesh[20].descriptor_ui | D020370 |
| mesh[20].is_major_topic | True |
| mesh[20].qualifier_name | drug therapy |
| mesh[20].descriptor_name | Osteoarthritis, Knee |
| mesh[21].qualifier_ui | Q000627 |
| mesh[21].descriptor_ui | D000894 |
| mesh[21].is_major_topic | True |
| mesh[21].qualifier_name | therapeutic use |
| mesh[21].descriptor_name | Anti-Inflammatory Agents, Non-Steroidal |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D005260 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Female |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D008297 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Male |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D008875 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Middle Aged |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D026741 |
| mesh[25].is_major_topic | True |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Physical Therapy Modalities |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D000368 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Aged |
| type | article |
| title | The therapeutic benefits of NSAIDs and physical therapy in knee osteoarthritis |
| biblio.issue | 2 |
| biblio.volume | 65 |
| biblio.last_page | 224 |
| biblio.first_page | 217 |
| topics[0].id | https://openalex.org/T10105 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9998999834060669 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2745 |
| topics[0].subfield.display_name | Rheumatology |
| topics[0].display_name | Osteoarthritis Treatment and Mechanisms |
| topics[1].id | https://openalex.org/T10678 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9991000294685364 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2736 |
| topics[1].subfield.display_name | Pharmacology |
| topics[1].display_name | Inflammatory mediators and NSAID effects |
| topics[2].id | https://openalex.org/T11532 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9710999727249146 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2730 |
| topics[2].subfield.display_name | Oncology |
| topics[2].display_name | Chemokine receptors and signaling |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C2776164576 |
| concepts[0].level | 3 |
| concepts[0].score | 0.9408149719238281 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q62736 |
| concepts[0].display_name | Osteoarthritis |
| concepts[1].id | https://openalex.org/C71924100 |
| concepts[1].level | 0 |
| concepts[1].score | 0.869888186454773 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[1].display_name | Medicine |
| concepts[2].id | https://openalex.org/C2779134260 |
| concepts[2].level | 2 |
| concepts[2].score | 0.5986261367797852 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q12136 |
| concepts[2].display_name | Disease |
| concepts[3].id | https://openalex.org/C1862650 |
| concepts[3].level | 1 |
| concepts[3].score | 0.5319139361381531 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q186005 |
| concepts[3].display_name | Physical therapy |
| concepts[4].id | https://openalex.org/C2908736133 |
| concepts[4].level | 2 |
| concepts[4].score | 0.5114744901657104 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q37425 |
| concepts[4].display_name | Knee Joint |
| concepts[5].id | https://openalex.org/C2778384578 |
| concepts[5].level | 3 |
| concepts[5].score | 0.43644213676452637 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q16930687 |
| concepts[5].display_name | Therapeutic approach |
| concepts[6].id | https://openalex.org/C126322002 |
| concepts[6].level | 1 |
| concepts[6].score | 0.2205633521080017 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[6].display_name | Internal medicine |
| concepts[7].id | https://openalex.org/C141071460 |
| concepts[7].level | 1 |
| concepts[7].score | 0.1856207251548767 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q40821 |
| concepts[7].display_name | Surgery |
| concepts[8].id | https://openalex.org/C204787440 |
| concepts[8].level | 2 |
| concepts[8].score | 0.17824390530586243 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q188504 |
| concepts[8].display_name | Alternative medicine |
| concepts[9].id | https://openalex.org/C142724271 |
| concepts[9].level | 1 |
| concepts[9].score | 0.12300395965576172 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q7208 |
| concepts[9].display_name | Pathology |
| keywords[0].id | https://openalex.org/keywords/osteoarthritis |
| keywords[0].score | 0.9408149719238281 |
| keywords[0].display_name | Osteoarthritis |
| keywords[1].id | https://openalex.org/keywords/medicine |
| keywords[1].score | 0.869888186454773 |
| keywords[1].display_name | Medicine |
| keywords[2].id | https://openalex.org/keywords/disease |
| keywords[2].score | 0.5986261367797852 |
| keywords[2].display_name | Disease |
| keywords[3].id | https://openalex.org/keywords/physical-therapy |
| keywords[3].score | 0.5319139361381531 |
| keywords[3].display_name | Physical therapy |
| keywords[4].id | https://openalex.org/keywords/knee-joint |
| keywords[4].score | 0.5114744901657104 |
| keywords[4].display_name | Knee Joint |
| keywords[5].id | https://openalex.org/keywords/therapeutic-approach |
| keywords[5].score | 0.43644213676452637 |
| keywords[5].display_name | Therapeutic approach |
| keywords[6].id | https://openalex.org/keywords/internal-medicine |
| keywords[6].score | 0.2205633521080017 |
| keywords[6].display_name | Internal medicine |
| keywords[7].id | https://openalex.org/keywords/surgery |
| keywords[7].score | 0.1856207251548767 |
| keywords[7].display_name | Surgery |
| keywords[8].id | https://openalex.org/keywords/alternative-medicine |
| keywords[8].score | 0.17824390530586243 |
| keywords[8].display_name | Alternative medicine |
| keywords[9].id | https://openalex.org/keywords/pathology |
| keywords[9].score | 0.12300395965576172 |
| keywords[9].display_name | Pathology |
| language | en |
| locations[0].id | doi:10.47162/rjme.65.2.08 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S4210168708 |
| locations[0].source.issn | 1220-0522, 2066-8279 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 1220-0522 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Romanian Journal of Morphology and Embryology |
| locations[0].source.host_organization | https://openalex.org/P4310314685 |
| locations[0].source.host_organization_name | Romanian Academy's Publishing House |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310314685 |
| locations[0].source.host_organization_lineage_names | Romanian Academy's Publishing House |
| locations[0].license | |
| locations[0].pdf_url | https://rjme.ro/RJME/resources/files/650224217224.pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Romanian Journal of Morphology and Embryology |
| locations[0].landing_page_url | https://doi.org/10.47162/rjme.65.2.08 |
| locations[1].id | pmid:39020536 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/39020536 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:11384862 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Rom J Morphol Embryol |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11384862 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5040956167 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | George Ovidiu Cioroianu |
| authorships[0].countries | RO |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I28109999 |
| authorships[0].affiliations[0].raw_affiliation_string | ) Department of Physical Medicine and Rehabilitation, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I28109999 |
| authorships[0].affiliations[1].raw_affiliation_string | ) Doctoral School, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[0].institutions[0].id | https://openalex.org/I28109999 |
| authorships[0].institutions[0].ror | https://ror.org/031d5vw30 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I28109999 |
| authorships[0].institutions[0].country_code | RO |
| authorships[0].institutions[0].display_name | University of Medicine and Pharmacy of Craiova |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | George Ovidiu Cioroianu |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | ) Department of Physical Medicine and Rehabilitation, University of Medicine and Pharmacy of Craiova, Romania, ) Doctoral School, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[1].author.id | https://openalex.org/A5110947022 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Alesandra Florescu |
| authorships[1].countries | RO |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I28109999 |
| authorships[1].affiliations[0].raw_affiliation_string | ) Department of Rheumatology, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[1].institutions[0].id | https://openalex.org/I28109999 |
| authorships[1].institutions[0].ror | https://ror.org/031d5vw30 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I28109999 |
| authorships[1].institutions[0].country_code | RO |
| authorships[1].institutions[0].display_name | University of Medicine and Pharmacy of Craiova |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Alesandra Florescu |
| authorships[1].is_corresponding | True |
| authorships[1].raw_affiliation_strings | ) Department of Rheumatology, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[2].author.id | https://openalex.org/A5104772648 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Cristiana Eugenia Simionescu |
| authorships[2].countries | RO |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I28109999 |
| authorships[2].affiliations[0].raw_affiliation_string | ) Department of Pathology, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[2].institutions[0].id | https://openalex.org/I28109999 |
| authorships[2].institutions[0].ror | https://ror.org/031d5vw30 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I28109999 |
| authorships[2].institutions[0].country_code | RO |
| authorships[2].institutions[0].display_name | University of Medicine and Pharmacy of Craiova |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Cristiana Eugenia Simionescu |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | ) Department of Pathology, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[3].author.id | https://openalex.org/A5023440284 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Teodor Nicuşor Sas |
| authorships[3].countries | RO |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I28109999 |
| authorships[3].affiliations[0].raw_affiliation_string | ) Department of Radiology and Medical Imaging, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[3].institutions[0].id | https://openalex.org/I28109999 |
| authorships[3].institutions[0].ror | https://ror.org/031d5vw30 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I28109999 |
| authorships[3].institutions[0].country_code | RO |
| authorships[3].institutions[0].display_name | University of Medicine and Pharmacy of Craiova |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Teodor Nicuşor Sas |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | ) Department of Radiology and Medical Imaging, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[4].author.id | https://openalex.org/A5021957486 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-6935-6641 |
| authorships[4].author.display_name | Daniela Tarniţă |
| authorships[4].countries | RO |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I28109999 |
| authorships[4].affiliations[0].raw_affiliation_string | ) Department of Orthopedics and Traumatology, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[4].institutions[0].id | https://openalex.org/I28109999 |
| authorships[4].institutions[0].ror | https://ror.org/031d5vw30 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I28109999 |
| authorships[4].institutions[0].country_code | RO |
| authorships[4].institutions[0].display_name | University of Medicine and Pharmacy of Craiova |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Dănuţ Nicolae Tarniţă |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | ) Department of Orthopedics and Traumatology, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[5].author.id | https://openalex.org/A5113885250 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Otilia Constantina Rogoveanu |
| authorships[5].countries | RO |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I28109999 |
| authorships[5].affiliations[0].raw_affiliation_string | ) Department of Physical Medicine and Rehabilitation, University of Medicine and Pharmacy of Craiova, Romania |
| authorships[5].institutions[0].id | https://openalex.org/I28109999 |
| authorships[5].institutions[0].ror | https://ror.org/031d5vw30 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I28109999 |
| authorships[5].institutions[0].country_code | RO |
| authorships[5].institutions[0].display_name | University of Medicine and Pharmacy of Craiova |
| authorships[5].author_position | last |
| authorships[5].raw_author_name | Otilia Constantina Rogoveanu |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | ) Department of Physical Medicine and Rehabilitation, University of Medicine and Pharmacy of Craiova, Romania |
| has_content.pdf | True |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://rjme.ro/RJME/resources/files/650224217224.pdf |
| open_access.oa_status | diamond |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | The therapeutic benefits of NSAIDs and physical therapy in knee osteoarthritis |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10105 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9998999834060669 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2745 |
| primary_topic.subfield.display_name | Rheumatology |
| primary_topic.display_name | Osteoarthritis Treatment and Mechanisms |
| related_works | https://openalex.org/W650762618, https://openalex.org/W4242815383, https://openalex.org/W2579996474, https://openalex.org/W4386590483, https://openalex.org/W2346491184, https://openalex.org/W2976301780, https://openalex.org/W2360561200, https://openalex.org/W3177426155, https://openalex.org/W2377082163, https://openalex.org/W3028956932 |
| cited_by_count | 6 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 5 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 1 |
| locations_count | 3 |
| best_oa_location.id | doi:10.47162/rjme.65.2.08 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4210168708 |
| best_oa_location.source.issn | 1220-0522, 2066-8279 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 1220-0522 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Romanian Journal of Morphology and Embryology |
| best_oa_location.source.host_organization | https://openalex.org/P4310314685 |
| best_oa_location.source.host_organization_name | Romanian Academy's Publishing House |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310314685 |
| best_oa_location.source.host_organization_lineage_names | Romanian Academy's Publishing House |
| best_oa_location.license | |
| best_oa_location.pdf_url | https://rjme.ro/RJME/resources/files/650224217224.pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Romanian Journal of Morphology and Embryology |
| best_oa_location.landing_page_url | https://doi.org/10.47162/rjme.65.2.08 |
| primary_location.id | doi:10.47162/rjme.65.2.08 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S4210168708 |
| primary_location.source.issn | 1220-0522, 2066-8279 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 1220-0522 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Romanian Journal of Morphology and Embryology |
| primary_location.source.host_organization | https://openalex.org/P4310314685 |
| primary_location.source.host_organization_name | Romanian Academy's Publishing House |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310314685 |
| primary_location.source.host_organization_lineage_names | Romanian Academy's Publishing House |
| primary_location.license | |
| primary_location.pdf_url | https://rjme.ro/RJME/resources/files/650224217224.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Romanian Journal of Morphology and Embryology |
| primary_location.landing_page_url | https://doi.org/10.47162/rjme.65.2.08 |
| publication_date | 2024-07-15 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W2027831505, https://openalex.org/W179053432, https://openalex.org/W2140513563, https://openalex.org/W4211067786, https://openalex.org/W2052853106, https://openalex.org/W2176454608, https://openalex.org/W2518546450, https://openalex.org/W2116431503, https://openalex.org/W2281431176, https://openalex.org/W2537149327, https://openalex.org/W4293218908, https://openalex.org/W2133075927, https://openalex.org/W2982638166, https://openalex.org/W2934693249, https://openalex.org/W3133854280, https://openalex.org/W1716794597, https://openalex.org/W2253579545, https://openalex.org/W1971496705, https://openalex.org/W2037195415, https://openalex.org/W2028902332, https://openalex.org/W2099427592, https://openalex.org/W4233138142, https://openalex.org/W2161736885, https://openalex.org/W2943119591, https://openalex.org/W2286191622, https://openalex.org/W2944136715, https://openalex.org/W2605094439, https://openalex.org/W3206683668, https://openalex.org/W2129281457, https://openalex.org/W4206026455, https://openalex.org/W3216876608, https://openalex.org/W2529416453, https://openalex.org/W2050305815, https://openalex.org/W3208312364, https://openalex.org/W2982565448, https://openalex.org/W6979089650, https://openalex.org/W3149439301, https://openalex.org/W2147683491, https://openalex.org/W4285044096, https://openalex.org/W2999494008, https://openalex.org/W3000036091 |
| referenced_works_count | 41 |
| abstract_inverted_index.a | 7, 20, 147, 175, 202, 229, 261 |
| abstract_inverted_index.(a | 136 |
| abstract_inverted_index.10 | 129 |
| abstract_inverted_index.24 | 231 |
| abstract_inverted_index.46 | 81 |
| abstract_inverted_index.as | 6, 131 |
| abstract_inverted_index.at | 33, 99 |
| abstract_inverted_index.if | 241 |
| abstract_inverted_index.in | 67, 151, 179, 260, 275 |
| abstract_inverted_index.is | 27 |
| abstract_inverted_index.no | 28, 126, 215 |
| abstract_inverted_index.of | 13, 23, 44, 55, 59, 70, 94, 105, 121, 139, 186, 236, 263, 273 |
| abstract_inverted_index.on | 40 |
| abstract_inverted_index.to | 50, 91, 239 |
| abstract_inverted_index.150 | 124 |
| abstract_inverted_index.All | 114 |
| abstract_inverted_index.KOA | 87 |
| abstract_inverted_index.OKS | 258 |
| abstract_inverted_index.Our | 47, 250 |
| abstract_inverted_index.The | 78, 143, 199, 267 |
| abstract_inverted_index.VAS | 208, 219 |
| abstract_inverted_index.and | 10, 64, 76, 88, 97, 111, 133, 157, 164, 191, 210, 221, 257, 283 |
| abstract_inverted_index.but | 214 |
| abstract_inverted_index.for | 228 |
| abstract_inverted_index.has | 3 |
| abstract_inverted_index.see | 240 |
| abstract_inverted_index.the | 14, 34, 36, 41, 45, 52, 56, 68, 92, 100, 115, 118, 153, 165, 181, 192, 234, 237, 253, 271 |
| abstract_inverted_index.use | 58 |
| abstract_inverted_index.was | 174, 244 |
| abstract_inverted_index.who | 83 |
| abstract_inverted_index.(OA) | 2 |
| abstract_inverted_index.2021 | 110 |
| abstract_inverted_index.KOA. | 266 |
| abstract_inverted_index.Knee | 183, 195 |
| abstract_inverted_index.VAS, | 255 |
| abstract_inverted_index.also | 18 |
| abstract_inverted_index.been | 4 |
| abstract_inverted_index.both | 152, 180 |
| abstract_inverted_index.knee | 71 |
| abstract_inverted_index.more | 127 |
| abstract_inverted_index.pain | 282 |
| abstract_inverted_index.plan | 138 |
| abstract_inverted_index.same | 119 |
| abstract_inverted_index.tear | 11 |
| abstract_inverted_index.than | 128 |
| abstract_inverted_index.that | 270 |
| abstract_inverted_index.this | 247 |
| abstract_inverted_index.wear | 9 |
| abstract_inverted_index.were | 84, 89, 226 |
| abstract_inverted_index.with | 86, 265, 277 |
| abstract_inverted_index.(OKS) | 197 |
| abstract_inverted_index.(VAS) | 170 |
| abstract_inverted_index.2022. | 113 |
| abstract_inverted_index.April | 112 |
| abstract_inverted_index.Daily | 187 |
| abstract_inverted_index.Scale | 169 |
| abstract_inverted_index.Score | 196 |
| abstract_inverted_index.aimed | 49 |
| abstract_inverted_index.drugs | 62 |
| abstract_inverted_index.focus | 39 |
| abstract_inverted_index.found | 201 |
| abstract_inverted_index.group | 145 |
| abstract_inverted_index.index | 162 |
| abstract_inverted_index.joint | 285 |
| abstract_inverted_index.study | 48, 79, 200 |
| abstract_inverted_index.there | 26, 173 |
| abstract_inverted_index.time. | 248 |
| abstract_inverted_index.weeks | 232 |
| abstract_inverted_index.which | 17 |
| abstract_inverted_index.(KOA). | 73 |
| abstract_inverted_index.Analog | 168 |
| abstract_inverted_index.County | 103 |
| abstract_inverted_index.Living | 188 |
| abstract_inverted_index.NSAIDs | 274 |
| abstract_inverted_index.Oxford | 194 |
| abstract_inverted_index.Visual | 167 |
| abstract_inverted_index.WOMAC, | 254 |
| abstract_inverted_index.beyond | 233 |
| abstract_inverted_index.cohort | 262 |
| abstract_inverted_index.degree | 22 |
| abstract_inverted_index.during | 246 |
| abstract_inverted_index.higher | 207 |
| abstract_inverted_index.levels | 212, 223 |
| abstract_inverted_index.scores | 220 |
| abstract_inverted_index.(WOMAC) | 161 |
| abstract_inverted_index.24-week | 137 |
| abstract_inverted_index.January | 109 |
| abstract_inverted_index.Ontario | 156 |
| abstract_inverted_index.Outcome | 184 |
| abstract_inverted_index.Western | 155 |
| abstract_inverted_index.average | 154, 166, 182, 193 |
| abstract_inverted_index.between | 108, 206, 218 |
| abstract_inverted_index.certain | 21 |
| abstract_inverted_index.current | 37 |
| abstract_inverted_index.disease | 12, 29 |
| abstract_inverted_index.further | 230 |
| abstract_inverted_index.joints, | 16 |
| abstract_inverted_index.mg/day, | 125 |
| abstract_inverted_index.moment, | 35 |
| abstract_inverted_index.needed) | 132 |
| abstract_inverted_index.patient | 144 |
| abstract_inverted_index.ratings | 209 |
| abstract_inverted_index.results | 268 |
| abstract_inverted_index.therapy | 66, 279 |
| abstract_inverted_index.tracked | 252 |
| abstract_inverted_index.(NSAIDs) | 63 |
| abstract_inverted_index.Clinical | 102 |
| abstract_inverted_index.Craiova, | 106 |
| abstract_inverted_index.Hospital | 104 |
| abstract_inverted_index.McMaster | 158 |
| abstract_inverted_index.Medicine | 96 |
| abstract_inverted_index.Methods: | 77 |
| abstract_inverted_index.Patients | 225 |
| abstract_inverted_index.Physical | 95 |
| abstract_inverted_index.Results: | 142 |
| abstract_inverted_index.Romania, | 107 |
| abstract_inverted_index.admitted | 90 |
| abstract_inverted_index.enhances | 284 |
| abstract_inverted_index.evaluate | 51 |
| abstract_inverted_index.increase | 178 |
| abstract_inverted_index.involves | 19 |
| abstract_inverted_index.patients | 264 |
| abstract_inverted_index.physical | 65, 140, 278 |
| abstract_inverted_index.positive | 204 |
| abstract_inverted_index.received | 117 |
| abstract_inverted_index.research | 238 |
| abstract_inverted_index.surgical | 242 |
| abstract_inverted_index.synovial | 15 |
| abstract_inverted_index.Emergency | 101 |
| abstract_inverted_index.Materials | 75 |
| abstract_inverted_index.Patients, | 74 |
| abstract_inverted_index.available | 32 |
| abstract_inverted_index.comprised | 80 |
| abstract_inverted_index.diagnosed | 85 |
| abstract_inverted_index.evaluated | 227 |
| abstract_inverted_index.exhibited | 146 |
| abstract_inverted_index.modifying | 30 |
| abstract_inverted_index.necessary | 245 |
| abstract_inverted_index.reduction | 150 |
| abstract_inverted_index.therapy). | 141 |
| abstract_inverted_index.treatment | 43, 69, 135 |
| abstract_inverted_index.(p=0.0128) | 190 |
| abstract_inverted_index.(p=0.0142) | 163 |
| abstract_inverted_index.Department | 93 |
| abstract_inverted_index.KOS–ADL, | 256 |
| abstract_inverted_index.advantages | 54 |
| abstract_inverted_index.affection. | 46 |
| abstract_inverted_index.alleviates | 281 |
| abstract_inverted_index.conclusion | 235 |
| abstract_inverted_index.days/month | 130 |
| abstract_inverted_index.guidelines | 38 |
| abstract_inverted_index.medication | 31 |
| abstract_inverted_index.(Diclofenac | 123 |
| abstract_inverted_index.(KOS–ADL) | 189 |
| abstract_inverted_index.(p=0.0023). | 171, 198 |
| abstract_inverted_index.(p=0.0092), | 213 |
| abstract_inverted_index.(p=0.0986). | 224 |
| abstract_inverted_index.Considering | 25 |
| abstract_inverted_index.cholesterol | 211 |
| abstract_inverted_index.combination | 120 |
| abstract_inverted_index.conjunction | 276 |
| abstract_inverted_index.correlation | 205, 217 |
| abstract_inverted_index.demonstrate | 269 |
| abstract_inverted_index.effectively | 280 |
| abstract_inverted_index.established | 5 |
| abstract_inverted_index.individuals | 82 |
| abstract_inverted_index.progressive | 8 |
| abstract_inverted_index.significant | 149, 177, 203, 216 |
| abstract_inverted_index.symptomatic | 42 |
| abstract_inverted_index.synergistic | 57 |
| abstract_inverted_index.therapeutic | 53 |
| abstract_inverted_index.utilization | 272 |
| abstract_inverted_index.Conclusions: | 249 |
| abstract_inverted_index.Universities | 159 |
| abstract_inverted_index.intervention | 243 |
| abstract_inverted_index.measurements | 259 |
| abstract_inverted_index.participants | 116 |
| abstract_inverted_index.triglyceride | 222 |
| abstract_inverted_index.Additionally, | 172 |
| abstract_inverted_index.Introduction: | 0 |
| abstract_inverted_index.inflammation. | 24 |
| abstract_inverted_index.investigation | 251 |
| abstract_inverted_index.non-steroidal | 60 |
| abstract_inverted_index.statistically | 148, 176 |
| abstract_inverted_index.Osteoarthritis | 1, 160 |
| abstract_inverted_index.Rehabilitation | 98 |
| abstract_inverted_index.functionality. | 286 |
| abstract_inverted_index.osteoarthritis | 72 |
| abstract_inverted_index.pharmacological | 122 |
| abstract_inverted_index.anti-inflammatory | 61 |
| abstract_inverted_index.Survey–Activities | 185 |
| abstract_inverted_index.non-pharmacological | 134 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 90 |
| corresponding_author_ids | https://openalex.org/A5110947022 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 6 |
| corresponding_institution_ids | https://openalex.org/I28109999 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.8500000238418579 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.93314809 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |