The use of scaffold technologies to optimize the healing of skin wounds Article Swipe
YOU?
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· 2025
· Open Access
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· DOI: https://doi.org/10.21518/akh2025-044
Chronic wound care and wound healing management are a global public health burden that accounts for approximately 3% of total healthcare expenditure. Current therapeutic strategies used by healthcare institutions struggle to effectively handle the wound treatment, which results in long-term hospital stays. The gravity of the situation is compounded by the continuous growth of risk factors associated with chronic wound development. Therefore, it is necessary to investigate the treatment solutions that can restart wound healing by targeting specific mechanisms involved in wound repair. The article discusses topical issues of the improvement of skin wound healing by using scaffolds. The authors provide a review of current advancements in skin tissue regeneration, highlighting scaffold technologies. Today, scaffold technologies is an essential tool in different areas of regenerative medicine. The efficiency of these technologies is undoubtedly associated with their specific mechanisms aimed at providing mechanical support to reproduce the potential wound defect scaffold. Assessment of such potential requires studying the reaction of recipient tissues to matrix integration in vivo and determining the patterns of collagen fiber formation. We have analysed data from foreign and domestic sources using the search engines PubMed® and elibrary.ru over the past years. The review covers a broad spectrum of issues ranging from general principles of wound healing to a detailed description of various types of scaffolds, addressing all the key aspects of scaffold technologies. Detailed review of different types of scaffolds, their composition, properties and benefits when used to improve skin regeneration mechanisms is provided.
Related Topics
- Type
- article
- Landing Page
- https://doi.org/10.21518/akh2025-044
- https://www.a-surgeon.ru/jour/article/download/597/476
- OA Status
- diamond
- References
- 60
- OpenAlex ID
- https://openalex.org/W7106611815
Raw OpenAlex JSON
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https://openalex.org/W7106611815Canonical identifier for this work in OpenAlex
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https://doi.org/10.21518/akh2025-044Digital Object Identifier
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The use of scaffold technologies to optimize the healing of skin woundsWork title
- Type
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articleOpenAlex work type
- Publication year
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2025Year of publication
- Publication date
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2025-11-25Full publication date if available
- Authors
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M. M. Mironov, K.I. Sergatskiy, V.I. Nikolsky, V.S. Romanova, A V Shabrov, A.D. ZakharovList of authors in order
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https://doi.org/10.21518/akh2025-044Publisher landing page
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https://www.a-surgeon.ru/jour/article/download/597/476Direct link to full text PDF
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://www.a-surgeon.ru/jour/article/download/597/476Direct OA link when available
- Concepts
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Wound healing, Wound care, Scaffold, Medicine, Regeneration (biology), Health care, Chronic wound, Risk analysis (engineering), Biomedical engineering, Intensive care medicine, Collagen fiber, Skin repair, Tissue repair, Emerging technologies, Broad spectrum, Wound dressing, Tissue engineering, Surgery, Regenerative medicine, Standard of care, Computer scienceTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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60Number of works referenced by this work
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| abstract_inverted_index.in | 38, 80, 106, 120, 164 |
| abstract_inverted_index.is | 47, 63, 116, 131, 245 |
| abstract_inverted_index.it | 62 |
| abstract_inverted_index.of | 18, 44, 53, 88, 91, 103, 123, 128, 151, 158, 170, 200, 206, 213, 216, 223, 228, 231 |
| abstract_inverted_index.to | 30, 65, 143, 161, 209, 240 |
| abstract_inverted_index.The | 42, 83, 98, 126, 194 |
| abstract_inverted_index.all | 219 |
| abstract_inverted_index.and | 3, 166, 180, 188, 236 |
| abstract_inverted_index.are | 7 |
| abstract_inverted_index.can | 71 |
| abstract_inverted_index.for | 15 |
| abstract_inverted_index.key | 221 |
| abstract_inverted_index.the | 33, 45, 50, 67, 89, 145, 156, 168, 184, 191, 220 |
| abstract_inverted_index.care | 2 |
| abstract_inverted_index.data | 177 |
| abstract_inverted_index.from | 178, 203 |
| abstract_inverted_index.have | 175 |
| abstract_inverted_index.over | 190 |
| abstract_inverted_index.past | 192 |
| abstract_inverted_index.risk | 54 |
| abstract_inverted_index.skin | 92, 107, 242 |
| abstract_inverted_index.such | 152 |
| abstract_inverted_index.that | 13, 70 |
| abstract_inverted_index.tool | 119 |
| abstract_inverted_index.used | 25, 239 |
| abstract_inverted_index.vivo | 165 |
| abstract_inverted_index.when | 238 |
| abstract_inverted_index.with | 57, 134 |
| abstract_inverted_index.aimed | 138 |
| abstract_inverted_index.areas | 122 |
| abstract_inverted_index.broad | 198 |
| abstract_inverted_index.fiber | 172 |
| abstract_inverted_index.their | 135, 233 |
| abstract_inverted_index.these | 129 |
| abstract_inverted_index.total | 19 |
| abstract_inverted_index.types | 215, 230 |
| abstract_inverted_index.using | 96, 183 |
| abstract_inverted_index.which | 36 |
| abstract_inverted_index.wound | 1, 4, 34, 59, 73, 81, 93, 147, 207 |
| abstract_inverted_index.Today, | 113 |
| abstract_inverted_index.burden | 12 |
| abstract_inverted_index.covers | 196 |
| abstract_inverted_index.defect | 148 |
| abstract_inverted_index.global | 9 |
| abstract_inverted_index.growth | 52 |
| abstract_inverted_index.handle | 32 |
| abstract_inverted_index.health | 11 |
| abstract_inverted_index.issues | 87, 201 |
| abstract_inverted_index.matrix | 162 |
| abstract_inverted_index.public | 10 |
| abstract_inverted_index.review | 102, 195, 227 |
| abstract_inverted_index.search | 185 |
| abstract_inverted_index.stays. | 41 |
| abstract_inverted_index.tissue | 108 |
| abstract_inverted_index.years. | 193 |
| abstract_inverted_index.Chronic | 0 |
| abstract_inverted_index.Current | 22 |
| abstract_inverted_index.article | 84 |
| abstract_inverted_index.aspects | 222 |
| abstract_inverted_index.authors | 99 |
| abstract_inverted_index.chronic | 58 |
| abstract_inverted_index.current | 104 |
| abstract_inverted_index.engines | 186 |
| abstract_inverted_index.factors | 55 |
| abstract_inverted_index.foreign | 179 |
| abstract_inverted_index.general | 204 |
| abstract_inverted_index.gravity | 43 |
| abstract_inverted_index.healing | 5, 74, 94, 208 |
| abstract_inverted_index.improve | 241 |
| abstract_inverted_index.provide | 100 |
| abstract_inverted_index.ranging | 202 |
| abstract_inverted_index.repair. | 82 |
| abstract_inverted_index.restart | 72 |
| abstract_inverted_index.results | 37 |
| abstract_inverted_index.sources | 182 |
| abstract_inverted_index.support | 142 |
| abstract_inverted_index.tissues | 160 |
| abstract_inverted_index.topical | 86 |
| abstract_inverted_index.various | 214 |
| abstract_inverted_index.Detailed | 226 |
| abstract_inverted_index.PubMed® | 187 |
| abstract_inverted_index.accounts | 14 |
| abstract_inverted_index.analysed | 176 |
| abstract_inverted_index.benefits | 237 |
| abstract_inverted_index.collagen | 171 |
| abstract_inverted_index.detailed | 211 |
| abstract_inverted_index.domestic | 181 |
| abstract_inverted_index.hospital | 40 |
| abstract_inverted_index.involved | 79 |
| abstract_inverted_index.patterns | 169 |
| abstract_inverted_index.reaction | 157 |
| abstract_inverted_index.requires | 154 |
| abstract_inverted_index.scaffold | 111, 114, 224 |
| abstract_inverted_index.specific | 77, 136 |
| abstract_inverted_index.spectrum | 199 |
| abstract_inverted_index.struggle | 29 |
| abstract_inverted_index.studying | 155 |
| abstract_inverted_index.different | 121, 229 |
| abstract_inverted_index.discusses | 85 |
| abstract_inverted_index.essential | 118 |
| abstract_inverted_index.long-term | 39 |
| abstract_inverted_index.medicine. | 125 |
| abstract_inverted_index.necessary | 64 |
| abstract_inverted_index.potential | 146, 153 |
| abstract_inverted_index.provided. | 246 |
| abstract_inverted_index.providing | 140 |
| abstract_inverted_index.recipient | 159 |
| abstract_inverted_index.reproduce | 144 |
| abstract_inverted_index.scaffold. | 149 |
| abstract_inverted_index.situation | 46 |
| abstract_inverted_index.solutions | 69 |
| abstract_inverted_index.targeting | 76 |
| abstract_inverted_index.treatment | 68 |
| abstract_inverted_index.Assessment | 150 |
| abstract_inverted_index.Therefore, | 61 |
| abstract_inverted_index.addressing | 218 |
| abstract_inverted_index.associated | 56, 133 |
| abstract_inverted_index.compounded | 48 |
| abstract_inverted_index.continuous | 51 |
| abstract_inverted_index.efficiency | 127 |
| abstract_inverted_index.formation. | 173 |
| abstract_inverted_index.healthcare | 20, 27 |
| abstract_inverted_index.management | 6 |
| abstract_inverted_index.mechanical | 141 |
| abstract_inverted_index.mechanisms | 78, 137, 244 |
| abstract_inverted_index.principles | 205 |
| abstract_inverted_index.properties | 235 |
| abstract_inverted_index.scaffolds, | 217, 232 |
| abstract_inverted_index.scaffolds. | 97 |
| abstract_inverted_index.strategies | 24 |
| abstract_inverted_index.treatment, | 35 |
| abstract_inverted_index.description | 212 |
| abstract_inverted_index.determining | 167 |
| abstract_inverted_index.effectively | 31 |
| abstract_inverted_index.elibrary.ru | 189 |
| abstract_inverted_index.improvement | 90 |
| abstract_inverted_index.integration | 163 |
| abstract_inverted_index.investigate | 66 |
| abstract_inverted_index.therapeutic | 23 |
| abstract_inverted_index.undoubtedly | 132 |
| abstract_inverted_index.advancements | 105 |
| abstract_inverted_index.composition, | 234 |
| abstract_inverted_index.development. | 60 |
| abstract_inverted_index.expenditure. | 21 |
| abstract_inverted_index.highlighting | 110 |
| abstract_inverted_index.institutions | 28 |
| abstract_inverted_index.regeneration | 243 |
| abstract_inverted_index.regenerative | 124 |
| abstract_inverted_index.technologies | 115, 130 |
| abstract_inverted_index.approximately | 16 |
| abstract_inverted_index.regeneration, | 109 |
| abstract_inverted_index.technologies. | 112, 225 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 6 |
| citation_normalized_percentile |