Three new rotenoids from the stems of Derris elliptica and their anti-microbial activity Article Swipe
Thi Thu Trang Bui
,
Nguyen Thi Huong
,
Tuan Anh Nguyen
,
Phan Thị Thanh Hương
,
Nguyễn Xuân Nhiệm
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1080/14786419.2022.2132243
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1080/14786419.2022.2132243
Three new rotenoids, named derieliptosides A-C (1–3), were isolated from the stems of Derris elliptica (Wall.) Benth. Their structures were determined by HR-ESI-MS and NMR spectroscopic methods. Absolute configurations of them were elucidated by analysis of ECD spectra in comparison with TD-DFT calculation. Compounds 1–3 inhibited the growth of fungus Candida albicans and selectively inhibited bacterial strains. Of these, compound 1 showed selective inhibition on the growth of Enterococcus faecalis (MIC: 37.5 µM and IC50: 10.6 µM), Staphylococcus aureus (MIC: 75 µM and IC50: 22.7 µM), and C. albicans (MIC: 37.5 µM and IC50: 11.2 µM).
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Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1080/14786419.2022.2132243
- OA Status
- green
- Cited By
- 5
- References
- 21
- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4304118440Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1080/14786419.2022.2132243Digital Object Identifier
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Three new rotenoids from the stems of Derris elliptica and their anti-microbial activityWork title
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articleOpenAlex work type
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-10-10Full publication date if available
- Authors
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Thi Thu Trang Bui, Nguyen Thi Huong, Tuan Anh Nguyen, Phan Thị Thanh Hương, Nguyễn Xuân NhiệmList of authors in order
- Landing page
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https://doi.org/10.1080/14786419.2022.2132243Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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greenOpen access status per OpenAlex
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https://figshare.com/articles/journal_contribution/Three_new_rotenoids_from_the_stems_of_i_Derris_elliptica_i_and_their_anti-microbial_activity/21304584Direct OA link when available
- Concepts
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Enterococcus faecalis, Candida albicans, Minimum inhibitory concentration, IC50, Staphylococcus aureus, Stereochemistry, Chemistry, Corpus albicans, Traditional medicine, Biology, Microbiology, Antimicrobial, Bacteria, In vitro, Biochemistry, Genetics, MedicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
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5Total citation count in OpenAlex
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2025: 3, 2024: 2Per-year citation counts (last 5 years)
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21Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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