Time‐restricted feeding regulates lipid metabolism under metabolic challenges Article Swipe
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1002/bies.202300157
Dysregulation of lipid metabolism is a commonly observed feature associated with metabolic syndrome and leads to the development of negative health outcomes such as obesity, diabetes mellitus, non‐alcoholic fatty liver disease, or atherosclerosis. Time‐restricted feeding/eating (TRF/TRE), an emerging dietary intervention, has been shown to promote pleiotropic health benefits including the alteration of diurnal expression of genes associated with lipid metabolism, as well as levels of lipid species. Although TRF likely induces a response in multiple organs leading to the modulation of lipid metabolism, a majority of the studies related to TRF effects on lipids have focused only on individual tissues, and furthermore there is a lack of insight into potential underlying mechanisms. In this review, we summarize the current insights regarding TRF effects on lipid metabolism and the potential mechanisms in adipose tissue, liver, skeletal muscle, and heart, and conclude by outlining possible avenues for future exploration.
Related Topics
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1002/bies.202300157
- OA Status
- green
- Cited By
- 18
- References
- 65
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4387728504
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4387728504Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1002/bies.202300157Digital Object Identifier
- Title
-
Time‐restricted feeding regulates lipid metabolism under metabolic challengesWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-10-18Full publication date if available
- Authors
-
Yiming Guo, Christopher Livelo, Girish C. MelkaniList of authors in order
- Landing page
-
https://doi.org/10.1002/bies.202300157Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://pmc.ncbi.nlm.nih.gov/articles/PMC10841423/pdf/nihms-1936633.pdfDirect OA link when available
- Concepts
-
Lipid metabolism, Biology, Adipose tissue, Obesity, Metabolism, Fatty liver, Endocrinology, Disease, Lipid accumulation, Metabolic syndrome, Internal medicine, MedicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
18Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 13, 2024: 5Per-year citation counts (last 5 years)
- References (count)
-
65Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4387728504 |
|---|---|
| doi | https://doi.org/10.1002/bies.202300157 |
| ids.doi | https://doi.org/10.1002/bies.202300157 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/37850554 |
| ids.openalex | https://openalex.org/W4387728504 |
| fwci | 5.35495795 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D050356 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Lipid Metabolism |
| mesh[2].qualifier_ui | Q000378 |
| mesh[2].descriptor_ui | D009765 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | metabolism |
| mesh[2].descriptor_name | Obesity |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D008099 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Liver |
| mesh[4].qualifier_ui | Q000378 |
| mesh[4].descriptor_ui | D000273 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | metabolism |
| mesh[4].descriptor_name | Adipose Tissue |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D004734 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Energy Metabolism |
| mesh[6].qualifier_ui | Q000502 |
| mesh[6].descriptor_ui | D002940 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | physiology |
| mesh[6].descriptor_name | Circadian Rhythm |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D006801 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Humans |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D050356 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Lipid Metabolism |
| mesh[9].qualifier_ui | Q000378 |
| mesh[9].descriptor_ui | D009765 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | metabolism |
| mesh[9].descriptor_name | Obesity |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D008099 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Liver |
| mesh[11].qualifier_ui | Q000378 |
| mesh[11].descriptor_ui | D000273 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | metabolism |
| mesh[11].descriptor_name | Adipose Tissue |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D004734 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Energy Metabolism |
| mesh[13].qualifier_ui | Q000502 |
| mesh[13].descriptor_ui | D002940 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | physiology |
| mesh[13].descriptor_name | Circadian Rhythm |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D006801 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Humans |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D050356 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Lipid Metabolism |
| mesh[16].qualifier_ui | Q000378 |
| mesh[16].descriptor_ui | D009765 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | metabolism |
| mesh[16].descriptor_name | Obesity |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D008099 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Liver |
| mesh[18].qualifier_ui | Q000378 |
| mesh[18].descriptor_ui | D000273 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | metabolism |
| mesh[18].descriptor_name | Adipose Tissue |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D004734 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | Energy Metabolism |
| mesh[20].qualifier_ui | Q000502 |
| mesh[20].descriptor_ui | D002940 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | physiology |
| mesh[20].descriptor_name | Circadian Rhythm |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D006801 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Humans |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D050356 |
| mesh[22].is_major_topic | True |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Lipid Metabolism |
| mesh[23].qualifier_ui | Q000378 |
| mesh[23].descriptor_ui | D009765 |
| mesh[23].is_major_topic | True |
| mesh[23].qualifier_name | metabolism |
| mesh[23].descriptor_name | Obesity |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D008099 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Liver |
| mesh[25].qualifier_ui | Q000378 |
| mesh[25].descriptor_ui | D000273 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | metabolism |
| mesh[25].descriptor_name | Adipose Tissue |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D004734 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Energy Metabolism |
| mesh[27].qualifier_ui | Q000502 |
| mesh[27].descriptor_ui | D002940 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | physiology |
| mesh[27].descriptor_name | Circadian Rhythm |
| mesh[28].qualifier_ui | |
| mesh[28].descriptor_ui | D006801 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | |
| mesh[28].descriptor_name | Humans |
| mesh[29].qualifier_ui | |
| mesh[29].descriptor_ui | D050356 |
| mesh[29].is_major_topic | True |
| mesh[29].qualifier_name | |
| mesh[29].descriptor_name | Lipid Metabolism |
| mesh[30].qualifier_ui | Q000378 |
| mesh[30].descriptor_ui | D009765 |
| mesh[30].is_major_topic | True |
| mesh[30].qualifier_name | metabolism |
| mesh[30].descriptor_name | Obesity |
| mesh[31].qualifier_ui | |
| mesh[31].descriptor_ui | D008099 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | |
| mesh[31].descriptor_name | Liver |
| mesh[32].qualifier_ui | Q000378 |
| mesh[32].descriptor_ui | D000273 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | metabolism |
| mesh[32].descriptor_name | Adipose Tissue |
| mesh[33].qualifier_ui | |
| mesh[33].descriptor_ui | D004734 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | |
| mesh[33].descriptor_name | Energy Metabolism |
| mesh[34].qualifier_ui | Q000502 |
| mesh[34].descriptor_ui | D002940 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | physiology |
| mesh[34].descriptor_name | Circadian Rhythm |
| mesh[35].qualifier_ui | |
| mesh[35].descriptor_ui | D006801 |
| mesh[35].is_major_topic | False |
| mesh[35].qualifier_name | |
| mesh[35].descriptor_name | Humans |
| mesh[36].qualifier_ui | |
| mesh[36].descriptor_ui | D050356 |
| mesh[36].is_major_topic | True |
| mesh[36].qualifier_name | |
| mesh[36].descriptor_name | Lipid Metabolism |
| mesh[37].qualifier_ui | Q000378 |
| mesh[37].descriptor_ui | D009765 |
| mesh[37].is_major_topic | True |
| mesh[37].qualifier_name | metabolism |
| mesh[37].descriptor_name | Obesity |
| mesh[38].qualifier_ui | |
| mesh[38].descriptor_ui | D008099 |
| mesh[38].is_major_topic | False |
| mesh[38].qualifier_name | |
| mesh[38].descriptor_name | Liver |
| mesh[39].qualifier_ui | Q000378 |
| mesh[39].descriptor_ui | D000273 |
| mesh[39].is_major_topic | False |
| mesh[39].qualifier_name | metabolism |
| mesh[39].descriptor_name | Adipose Tissue |
| mesh[40].qualifier_ui | |
| mesh[40].descriptor_ui | D004734 |
| mesh[40].is_major_topic | False |
| mesh[40].qualifier_name | |
| mesh[40].descriptor_name | Energy Metabolism |
| mesh[41].qualifier_ui | Q000502 |
| mesh[41].descriptor_ui | D002940 |
| mesh[41].is_major_topic | False |
| mesh[41].qualifier_name | physiology |
| mesh[41].descriptor_name | Circadian Rhythm |
| mesh[42].qualifier_ui | |
| mesh[42].descriptor_ui | D006801 |
| mesh[42].is_major_topic | False |
| mesh[42].qualifier_name | |
| mesh[42].descriptor_name | Humans |
| mesh[43].qualifier_ui | |
| mesh[43].descriptor_ui | D050356 |
| mesh[43].is_major_topic | True |
| mesh[43].qualifier_name | |
| mesh[43].descriptor_name | Lipid Metabolism |
| mesh[44].qualifier_ui | Q000378 |
| mesh[44].descriptor_ui | D009765 |
| mesh[44].is_major_topic | True |
| mesh[44].qualifier_name | metabolism |
| mesh[44].descriptor_name | Obesity |
| mesh[45].qualifier_ui | |
| mesh[45].descriptor_ui | D008099 |
| mesh[45].is_major_topic | False |
| mesh[45].qualifier_name | |
| mesh[45].descriptor_name | Liver |
| mesh[46].qualifier_ui | Q000378 |
| mesh[46].descriptor_ui | D000273 |
| mesh[46].is_major_topic | False |
| mesh[46].qualifier_name | metabolism |
| mesh[46].descriptor_name | Adipose Tissue |
| mesh[47].qualifier_ui | |
| mesh[47].descriptor_ui | D004734 |
| mesh[47].is_major_topic | False |
| mesh[47].qualifier_name | |
| mesh[47].descriptor_name | Energy Metabolism |
| mesh[48].qualifier_ui | Q000502 |
| mesh[48].descriptor_ui | D002940 |
| mesh[48].is_major_topic | False |
| mesh[48].qualifier_name | physiology |
| mesh[48].descriptor_name | Circadian Rhythm |
| mesh[49].qualifier_ui | |
| mesh[49].descriptor_ui | D006801 |
| mesh[49].is_major_topic | False |
| mesh[49].qualifier_name | |
| mesh[49].descriptor_name | Humans |
| type | review |
| title | Time‐restricted feeding regulates lipid metabolism under metabolic challenges |
| awards[0].id | https://openalex.org/G2317887873 |
| awards[0].funder_id | https://openalex.org/F4320332161 |
| awards[0].display_name | |
| awards[0].funder_award_id | AG065992 |
| awards[0].funder_display_name | National Institutes of Health |
| awards[1].id | https://openalex.org/G5282753237 |
| awards[1].funder_id | https://openalex.org/F4320332161 |
| awards[1].display_name | |
| awards[1].funder_award_id | AG068550 |
| awards[1].funder_display_name | National Institutes of Health |
| biblio.issue | 12 |
| biblio.volume | 45 |
| biblio.last_page | e2300157 |
| biblio.first_page | e2300157 |
| topics[0].id | https://openalex.org/T12745 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2737 |
| topics[0].subfield.display_name | Physiology |
| topics[0].display_name | Dietary Effects on Health |
| topics[1].id | https://openalex.org/T12267 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9980999827384949 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2737 |
| topics[1].subfield.display_name | Physiology |
| topics[1].display_name | Diet and metabolism studies |
| topics[2].id | https://openalex.org/T11457 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9939000010490417 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2737 |
| topics[2].subfield.display_name | Physiology |
| topics[2].display_name | Adipose Tissue and Metabolism |
| funders[0].id | https://openalex.org/F4320332161 |
| funders[0].ror | https://ror.org/01cwqze88 |
| funders[0].display_name | National Institutes of Health |
| is_xpac | False |
| apc_list.value | 4840 |
| apc_list.currency | USD |
| apc_list.value_usd | 4840 |
| apc_paid | |
| concepts[0].id | https://openalex.org/C4733338 |
| concepts[0].level | 2 |
| concepts[0].score | 0.8618849515914917 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q2792936 |
| concepts[0].display_name | Lipid metabolism |
| concepts[1].id | https://openalex.org/C86803240 |
| concepts[1].level | 0 |
| concepts[1].score | 0.645614743232727 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[1].display_name | Biology |
| concepts[2].id | https://openalex.org/C171089720 |
| concepts[2].level | 2 |
| concepts[2].score | 0.5860826373100281 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q193583 |
| concepts[2].display_name | Adipose tissue |
| concepts[3].id | https://openalex.org/C511355011 |
| concepts[3].level | 2 |
| concepts[3].score | 0.5670293569564819 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q12174 |
| concepts[3].display_name | Obesity |
| concepts[4].id | https://openalex.org/C62231903 |
| concepts[4].level | 2 |
| concepts[4].score | 0.5385891199111938 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q1057 |
| concepts[4].display_name | Metabolism |
| concepts[5].id | https://openalex.org/C2778772119 |
| concepts[5].level | 3 |
| concepts[5].score | 0.49698904156684875 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q6058862 |
| concepts[5].display_name | Fatty liver |
| concepts[6].id | https://openalex.org/C134018914 |
| concepts[6].level | 1 |
| concepts[6].score | 0.45222264528274536 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q162606 |
| concepts[6].display_name | Endocrinology |
| concepts[7].id | https://openalex.org/C2779134260 |
| concepts[7].level | 2 |
| concepts[7].score | 0.451369971036911 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q12136 |
| concepts[7].display_name | Disease |
| concepts[8].id | https://openalex.org/C2992125399 |
| concepts[8].level | 2 |
| concepts[8].score | 0.4472886323928833 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q2824461 |
| concepts[8].display_name | Lipid accumulation |
| concepts[9].id | https://openalex.org/C2780578515 |
| concepts[9].level | 3 |
| concepts[9].score | 0.419630765914917 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q657193 |
| concepts[9].display_name | Metabolic syndrome |
| concepts[10].id | https://openalex.org/C126322002 |
| concepts[10].level | 1 |
| concepts[10].score | 0.36359018087387085 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[10].display_name | Internal medicine |
| concepts[11].id | https://openalex.org/C71924100 |
| concepts[11].level | 0 |
| concepts[11].score | 0.2296505868434906 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[11].display_name | Medicine |
| keywords[0].id | https://openalex.org/keywords/lipid-metabolism |
| keywords[0].score | 0.8618849515914917 |
| keywords[0].display_name | Lipid metabolism |
| keywords[1].id | https://openalex.org/keywords/biology |
| keywords[1].score | 0.645614743232727 |
| keywords[1].display_name | Biology |
| keywords[2].id | https://openalex.org/keywords/adipose-tissue |
| keywords[2].score | 0.5860826373100281 |
| keywords[2].display_name | Adipose tissue |
| keywords[3].id | https://openalex.org/keywords/obesity |
| keywords[3].score | 0.5670293569564819 |
| keywords[3].display_name | Obesity |
| keywords[4].id | https://openalex.org/keywords/metabolism |
| keywords[4].score | 0.5385891199111938 |
| keywords[4].display_name | Metabolism |
| keywords[5].id | https://openalex.org/keywords/fatty-liver |
| keywords[5].score | 0.49698904156684875 |
| keywords[5].display_name | Fatty liver |
| keywords[6].id | https://openalex.org/keywords/endocrinology |
| keywords[6].score | 0.45222264528274536 |
| keywords[6].display_name | Endocrinology |
| keywords[7].id | https://openalex.org/keywords/disease |
| keywords[7].score | 0.451369971036911 |
| keywords[7].display_name | Disease |
| keywords[8].id | https://openalex.org/keywords/lipid-accumulation |
| keywords[8].score | 0.4472886323928833 |
| keywords[8].display_name | Lipid accumulation |
| keywords[9].id | https://openalex.org/keywords/metabolic-syndrome |
| keywords[9].score | 0.419630765914917 |
| keywords[9].display_name | Metabolic syndrome |
| keywords[10].id | https://openalex.org/keywords/internal-medicine |
| keywords[10].score | 0.36359018087387085 |
| keywords[10].display_name | Internal medicine |
| keywords[11].id | https://openalex.org/keywords/medicine |
| keywords[11].score | 0.2296505868434906 |
| keywords[11].display_name | Medicine |
| language | en |
| locations[0].id | doi:10.1002/bies.202300157 |
| locations[0].is_oa | False |
| locations[0].source.id | https://openalex.org/S27819959 |
| locations[0].source.issn | 0265-9247, 1521-1878 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0265-9247 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | BioEssays |
| locations[0].source.host_organization | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_name | Wiley |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_lineage_names | Wiley |
| locations[0].license | |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | BioEssays |
| locations[0].landing_page_url | https://doi.org/10.1002/bies.202300157 |
| locations[1].id | pmid:37850554 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | BioEssays : news and reviews in molecular, cellular and developmental biology |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/37850554 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:10841423 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | |
| locations[2].pdf_url | https://pmc.ncbi.nlm.nih.gov/articles/PMC10841423/pdf/nihms-1936633.pdf |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Bioessays |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/10841423 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5049627569 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-4212-3784 |
| authorships[0].author.display_name | Yiming Guo |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I32389192 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA |
| authorships[0].institutions[0].id | https://openalex.org/I32389192 |
| authorships[0].institutions[0].ror | https://ror.org/008s83205 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I32389192 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | University of Alabama at Birmingham |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Yiming Guo |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA |
| authorships[1].author.id | https://openalex.org/A5039498943 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Christopher Livelo |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I32389192 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA |
| authorships[1].institutions[0].id | https://openalex.org/I32389192 |
| authorships[1].institutions[0].ror | https://ror.org/008s83205 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I32389192 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | University of Alabama at Birmingham |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Christopher Livelo |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA |
| authorships[2].author.id | https://openalex.org/A5048760741 |
| authorships[2].author.orcid | https://orcid.org/0000-0003-0353-4633 |
| authorships[2].author.display_name | Girish C. Melkani |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I32389192 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA |
| authorships[2].institutions[0].id | https://openalex.org/I32389192 |
| authorships[2].institutions[0].ror | https://ror.org/008s83205 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I32389192 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | University of Alabama at Birmingham |
| authorships[2].author_position | last |
| authorships[2].raw_author_name | Girish C. Melkani |
| authorships[2].is_corresponding | True |
| authorships[2].raw_affiliation_strings | Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA |
| has_content.pdf | True |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://pmc.ncbi.nlm.nih.gov/articles/PMC10841423/pdf/nihms-1936633.pdf |
| open_access.oa_status | green |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Time‐restricted feeding regulates lipid metabolism under metabolic challenges |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T12745 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2737 |
| primary_topic.subfield.display_name | Physiology |
| primary_topic.display_name | Dietary Effects on Health |
| related_works | https://openalex.org/W3045014357, https://openalex.org/W2051786653, https://openalex.org/W2579576639, https://openalex.org/W3000094221, https://openalex.org/W2968051816, https://openalex.org/W2362961602, https://openalex.org/W2617159282, https://openalex.org/W2183539600, https://openalex.org/W2161883681, https://openalex.org/W3157593006 |
| cited_by_count | 18 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 13 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 5 |
| locations_count | 3 |
| best_oa_location.id | pmh:oai:pubmedcentral.nih.gov:10841423 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2764455111 |
| best_oa_location.source.issn | |
| best_oa_location.source.type | repository |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | PubMed Central |
| best_oa_location.source.host_organization | https://openalex.org/I1299303238 |
| best_oa_location.source.host_organization_name | National Institutes of Health |
| best_oa_location.source.host_organization_lineage | https://openalex.org/I1299303238 |
| best_oa_location.license | |
| best_oa_location.pdf_url | https://pmc.ncbi.nlm.nih.gov/articles/PMC10841423/pdf/nihms-1936633.pdf |
| best_oa_location.version | submittedVersion |
| best_oa_location.raw_type | Text |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | False |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | Bioessays |
| best_oa_location.landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/10841423 |
| primary_location.id | doi:10.1002/bies.202300157 |
| primary_location.is_oa | False |
| primary_location.source.id | https://openalex.org/S27819959 |
| primary_location.source.issn | 0265-9247, 1521-1878 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0265-9247 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | BioEssays |
| primary_location.source.host_organization | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_name | Wiley |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_lineage_names | Wiley |
| primary_location.license | |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | BioEssays |
| primary_location.landing_page_url | https://doi.org/10.1002/bies.202300157 |
| publication_date | 2023-10-18 |
| publication_year | 2023 |
| referenced_works | https://openalex.org/W1993357003, https://openalex.org/W2727069564, https://openalex.org/W3122805666, https://openalex.org/W3156627462, https://openalex.org/W3208605131, https://openalex.org/W2562488284, https://openalex.org/W3109390136, https://openalex.org/W2944154949, https://openalex.org/W2406151438, https://openalex.org/W3087759562, https://openalex.org/W1833481422, https://openalex.org/W2047324057, https://openalex.org/W4313531903, https://openalex.org/W2298864816, https://openalex.org/W2067096633, https://openalex.org/W2051051060, https://openalex.org/W2518904228, https://openalex.org/W4313432874, https://openalex.org/W2889094742, https://openalex.org/W3034258135, https://openalex.org/W2951235614, https://openalex.org/W2171666144, https://openalex.org/W2339913955, https://openalex.org/W3207990628, https://openalex.org/W3094179649, https://openalex.org/W4380224975, https://openalex.org/W2001671445, https://openalex.org/W2163810943, https://openalex.org/W2086482588, https://openalex.org/W4244189832, https://openalex.org/W2167351040, https://openalex.org/W2059613020, https://openalex.org/W2032487466, https://openalex.org/W2619337392, https://openalex.org/W2123319274, https://openalex.org/W3081770539, https://openalex.org/W2080019362, https://openalex.org/W2164135134, https://openalex.org/W2073742199, https://openalex.org/W2276696553, https://openalex.org/W2016408297, https://openalex.org/W2110839026, https://openalex.org/W1987849310, https://openalex.org/W1983050178, https://openalex.org/W2218084860, https://openalex.org/W2998776705, https://openalex.org/W2002711503, https://openalex.org/W4321455580, https://openalex.org/W1525052741, https://openalex.org/W3186151422, https://openalex.org/W1979759472, https://openalex.org/W2490533448, https://openalex.org/W2051695900, https://openalex.org/W1966875352, https://openalex.org/W2739272520, https://openalex.org/W2070647639, https://openalex.org/W1973520084, https://openalex.org/W2124966303, https://openalex.org/W3135107923, https://openalex.org/W2089504088, https://openalex.org/W1975439065, https://openalex.org/W3123521443, https://openalex.org/W2011010970, https://openalex.org/W4313271895, https://openalex.org/W1975418306 |
| referenced_works_count | 65 |
| abstract_inverted_index.a | 6, 72, 84, 105 |
| abstract_inverted_index.In | 113 |
| abstract_inverted_index.an | 37 |
| abstract_inverted_index.as | 24, 61, 63 |
| abstract_inverted_index.by | 141 |
| abstract_inverted_index.in | 74, 131 |
| abstract_inverted_index.is | 5, 104 |
| abstract_inverted_index.of | 2, 19, 52, 55, 65, 81, 86, 107 |
| abstract_inverted_index.on | 93, 98, 124 |
| abstract_inverted_index.or | 32 |
| abstract_inverted_index.to | 16, 44, 78, 90 |
| abstract_inverted_index.we | 116 |
| abstract_inverted_index.TRF | 69, 91, 122 |
| abstract_inverted_index.and | 14, 101, 127, 137, 139 |
| abstract_inverted_index.for | 145 |
| abstract_inverted_index.has | 41 |
| abstract_inverted_index.the | 17, 50, 79, 87, 118, 128 |
| abstract_inverted_index.been | 42 |
| abstract_inverted_index.have | 95 |
| abstract_inverted_index.into | 109 |
| abstract_inverted_index.lack | 106 |
| abstract_inverted_index.only | 97 |
| abstract_inverted_index.such | 23 |
| abstract_inverted_index.this | 114 |
| abstract_inverted_index.well | 62 |
| abstract_inverted_index.with | 11, 58 |
| abstract_inverted_index.fatty | 29 |
| abstract_inverted_index.genes | 56 |
| abstract_inverted_index.leads | 15 |
| abstract_inverted_index.lipid | 3, 59, 66, 82, 125 |
| abstract_inverted_index.liver | 30 |
| abstract_inverted_index.shown | 43 |
| abstract_inverted_index.there | 103 |
| abstract_inverted_index.future | 146 |
| abstract_inverted_index.health | 21, 47 |
| abstract_inverted_index.heart, | 138 |
| abstract_inverted_index.levels | 64 |
| abstract_inverted_index.likely | 70 |
| abstract_inverted_index.lipids | 94 |
| abstract_inverted_index.liver, | 134 |
| abstract_inverted_index.organs | 76 |
| abstract_inverted_index.adipose | 132 |
| abstract_inverted_index.avenues | 144 |
| abstract_inverted_index.current | 119 |
| abstract_inverted_index.dietary | 39 |
| abstract_inverted_index.diurnal | 53 |
| abstract_inverted_index.effects | 92, 123 |
| abstract_inverted_index.feature | 9 |
| abstract_inverted_index.focused | 96 |
| abstract_inverted_index.induces | 71 |
| abstract_inverted_index.insight | 108 |
| abstract_inverted_index.leading | 77 |
| abstract_inverted_index.muscle, | 136 |
| abstract_inverted_index.promote | 45 |
| abstract_inverted_index.related | 89 |
| abstract_inverted_index.review, | 115 |
| abstract_inverted_index.studies | 88 |
| abstract_inverted_index.tissue, | 133 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Although | 68 |
| abstract_inverted_index.benefits | 48 |
| abstract_inverted_index.commonly | 7 |
| abstract_inverted_index.conclude | 140 |
| abstract_inverted_index.diabetes | 26 |
| abstract_inverted_index.disease, | 31 |
| abstract_inverted_index.emerging | 38 |
| abstract_inverted_index.insights | 120 |
| abstract_inverted_index.majority | 85 |
| abstract_inverted_index.multiple | 75 |
| abstract_inverted_index.negative | 20 |
| abstract_inverted_index.obesity, | 25 |
| abstract_inverted_index.observed | 8 |
| abstract_inverted_index.outcomes | 22 |
| abstract_inverted_index.possible | 143 |
| abstract_inverted_index.response | 73 |
| abstract_inverted_index.skeletal | 135 |
| abstract_inverted_index.species. | 67 |
| abstract_inverted_index.syndrome | 13 |
| abstract_inverted_index.tissues, | 100 |
| abstract_inverted_index.including | 49 |
| abstract_inverted_index.mellitus, | 27 |
| abstract_inverted_index.metabolic | 12 |
| abstract_inverted_index.outlining | 142 |
| abstract_inverted_index.potential | 110, 129 |
| abstract_inverted_index.regarding | 121 |
| abstract_inverted_index.summarize | 117 |
| abstract_inverted_index.(TRF/TRE), | 36 |
| abstract_inverted_index.alteration | 51 |
| abstract_inverted_index.associated | 10, 57 |
| abstract_inverted_index.expression | 54 |
| abstract_inverted_index.individual | 99 |
| abstract_inverted_index.mechanisms | 130 |
| abstract_inverted_index.metabolism | 4, 126 |
| abstract_inverted_index.modulation | 80 |
| abstract_inverted_index.underlying | 111 |
| abstract_inverted_index.development | 18 |
| abstract_inverted_index.furthermore | 102 |
| abstract_inverted_index.mechanisms. | 112 |
| abstract_inverted_index.metabolism, | 60, 83 |
| abstract_inverted_index.pleiotropic | 46 |
| abstract_inverted_index.exploration. | 147 |
| abstract_inverted_index.Dysregulation | 1 |
| abstract_inverted_index.intervention, | 40 |
| abstract_inverted_index.feeding/eating | 35 |
| abstract_inverted_index.non‐alcoholic | 28 |
| abstract_inverted_index.atherosclerosis. | 33 |
| abstract_inverted_index.Time‐restricted | 34 |
| cited_by_percentile_year.max | 100 |
| cited_by_percentile_year.min | 98 |
| corresponding_author_ids | https://openalex.org/A5048760741 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 3 |
| corresponding_institution_ids | https://openalex.org/I32389192 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.6499999761581421 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.94099723 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |