Treatment interruptions affect biochemical failure rates in prostate cancer patients treated with proton beam therapy: Report from the multi-institutional proton collaborative group registry Article Swipe

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Prostate cancer Medicine Proton therapy Prostate Internal medicine Affect (linguistics) Cancer Oncology Radiation therapy Proton Psychology Quantum mechanics Communication Physics

James E. Han , John Wen‐Cheng Chang , L Rosen , William F. Hartsell , Henry Tsai , Jonathan Chen , Mark V. Mishra , Daniel A. Krauss , J. Isabelle Choi , Charles B. Simone , Shaakir Hasan ·

YOU? · · 2020 · Open Access · · DOI: https://doi.org/10.1016/j.ctro.2020.10.003 · OA: W3093987407

In the first analysis of its kind, the results suggest that TI in high risk PCa patients treated with PBT and ADT have worse BF rates. Interventions such as increased patient education, proper maintenance of proton facilities, and decreasing total treatment duration with alternative fractionation schedules may help avoid the unintended negative effects on tumor control due to TI. However, future analyses on a larger patient population is needed.