Treatment Preferences for Acute Allergic Reactions: A Discrete Choice Experiment Article Swipe
Sofia Löfvendahl
,
Emelie Andersson
,
Sara Olofsson
,
Karin Wahlberg
,
Leif Bjermer
,
Göran Tornling
,
Jonas Hjemlgren
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.36469/jheor.2024.117589
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.36469/jheor.2024.117589
Background: Timely treatment of acute allergic reactions (AARs) is important to minimize reaction severity. Corticosteroid tablets dissolved in water are commonly used in mainstay treatment. A new oral film that dissolves on the tongue provides a faster and less cumbersome alternative to tablets for corticosteroid administration during AARs. This study evaluated patients’ preferences for attributes related to administration mode of corticosteroids in AARs. Methods: A web-based survey was sent to a sample from the adult Swedish population (≥18 years) with experience of corticosteroid treatment for AAR. We assessed the willingness to pay (WTP) for attributes related to corticosteroid treatment by applying a discrete choice experiment (DCE) approach. DCE attributes were administration mode, time to symptom relief, and price. The WTP for each attribute was derived using the attribute’s coefficient in a logistic regression analysis. We specified a forced choice (FC) and an unforced choice (UC) model. In the FC model, the respondents chose between 2 hypothetical treatments and in the UC model, between any of 2 hypothetical treatments and their current treatment. Results: The final study population included 348 subjects, of which 80% were women. All the evaluated DCE attributes were significant predictors for the treatment choice (p<.001). In the FC model, the incremental WTP for an oral film compared with tablets was 409 Swedish kronor (SEK [≈€36.7]), with no other factors considered. In the UC model, the incremental WTP for the oral film compared with tablets was 574 SEK (≈€51.7). After considering the value of the respondents’ current treatment, the WTP for the oral film decreased to 336 SEK (≈€30.3). The total WTP was reduced by 17 SEK (≈€1.5) per minute of shorter time to symptom relief. Subgroup analyses showed that people with circulatory symptoms and experience of swallowing difficulties related to allergy medication had higher WTP for the oral film than the average respondent. Conclusion: The findings show a substantial economic benefit of the oral film vs tablets for patients with AARs in Sweden. This result remained also after compensation for the full value of the patients’ current treatment.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.36469/jheor.2024.117589
- https://jheor.org/article/117589.pdf
- OA Status
- gold
- References
- 30
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4399328834
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4399328834Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.36469/jheor.2024.117589Digital Object Identifier
- Title
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Treatment Preferences for Acute Allergic Reactions: A Discrete Choice ExperimentWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-06-04Full publication date if available
- Authors
-
Sofia Löfvendahl, Emelie Andersson, Sara Olofsson, Karin Wahlberg, Leif Bjermer, Göran Tornling, Jonas HjemlgrenList of authors in order
- Landing page
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https://doi.org/10.36469/jheor.2024.117589Publisher landing page
- PDF URL
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https://jheor.org/article/117589.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://jheor.org/article/117589.pdfDirect OA link when available
- Concepts
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Discrete choice, Allergic reaction, Medicine, Mathematics, Computer science, Immunology, Econometrics, AllergyTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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30Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| institutions_distinct_count | 7 |
| corresponding_institution_ids | https://openalex.org/I4210110521 |
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| citation_normalized_percentile.is_in_top_10_percent | False |