Trends in varicella mortality in the United States: Data from vital statistics and the national surveillance system Article Swipe
YOU?
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· 2015
· Open Access
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· DOI: https://doi.org/10.1080/21645515.2015.1008880
This manuscript describes trends in US varicella mortality using national vital statistics system data for 2008-2011, the first years of the routine 2-dose varicella vaccination program, and characteristics of varicella deaths reported to CDC during 1996-2013. We obtained data on deaths with varicella as underlying or contributing cause from the 2008-2011 Mortality Multiple Cause-of Death records and calculated rates to compare with the prevaccine and mature 1-dose varicella vaccination program eras. We also reviewed available records of varicella deaths reported to CDC through the national varicella death surveillance. The annual average age-adjusted mortality rate for varicella as the underlying cause was 0.05 per million population during 2008-2011, an 87% reduction from the prevaccine years. Varicella deaths among persons aged <20 y declined by 99% in 2008-2011 compared with prevaccine years. There was a 70% decline in varicella mortality rates among those <20 y in 2008-2011 compared to 2005-2007. Among the 83 deaths reported to CDC during 1996-2013 classified as likely due to varicella, 24 (29%) were among immunocompromised individuals. Five were among persons previously vaccinated with 1 dose of varicella vaccine. In conclusion, although the US varicella vaccination program has significantly reduced varicella disease burden, there are still opportunities to prevent varicella and its associated morbidity and mortality through routine varicella vaccination, catch-up vaccination, and ensuring that household contacts of immunocompromised persons have evidence of immunity.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1080/21645515.2015.1008880
- https://www.tandfonline.com/doi/pdf/10.1080/21645515.2015.1008880?needAccess=true
- OA Status
- bronze
- Cited By
- 26
- References
- 22
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W1520694616
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W1520694616Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1080/21645515.2015.1008880Digital Object Identifier
- Title
-
Trends in varicella mortality in the United States: Data from vital statistics and the national surveillance systemWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2015Year of publication
- Publication date
-
2015-03-04Full publication date if available
- Authors
-
Jessica Leung, Stephanie R. Bialek, Mona MarinList of authors in order
- Landing page
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https://doi.org/10.1080/21645515.2015.1008880Publisher landing page
- PDF URL
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https://www.tandfonline.com/doi/pdf/10.1080/21645515.2015.1008880?needAccess=trueDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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bronzeOpen access status per OpenAlex
- OA URL
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https://www.tandfonline.com/doi/pdf/10.1080/21645515.2015.1008880?needAccess=trueDirect OA link when available
- Concepts
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Medicine, Environmental health, Public health surveillance, Statistics, Virology, Public health, Nursing, MathematicsTop concepts (fields/topics) attached by OpenAlex
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26Total citation count in OpenAlex
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2025: 1, 2024: 2, 2023: 2, 2022: 2, 2021: 4Per-year citation counts (last 5 years)
- References (count)
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22Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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