Triamcinolone Acetonide-Assisted Visualization and Removal of Vitreous Cortex Remnants in Retinal Detachment: A Prospective Cohort Study Article Swipe
Francesco Faraldi
,
Carlo Lavia
,
Daniela Bacherini
,
Clara Rizzo
,
Maria Cristina Savastano
,
Marco Nassisi
,
Mariantonia Ferrara
,
Mary Romano
,
Stanislao Rizzo
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/diagnostics15151854
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/diagnostics15151854
Background/Objectives: In rhegmatogenous retinal detachment (RRD), vitreous cortex remnants (VCRs) may contribute to the development and progression of proliferative vitreoretinopathy (PVR). This study aimed to evaluate potential toxicity and trauma secondary to VCRs visualization and removal during pars plana vitrectomy (PPV) for RRD. Methods: Prospective study on patients with primary RRD who underwent PPV. Imaging assessment included widefield OCT (WF-OCT), ultra-WF retinography and fundus autofluorescence (FAF). During PPV, a filtered and diluted triamcinolone acetonide (TA) solution (20 mg/mL) was used to evaluate the presence and extension of VCRs, removed using an extendible diamond-dusted sweeper (EDDS). After six months, retinal and retinal pigment epithelium toxicity and retinal trauma due to VCRs removal were investigated. Results: Retinal reattachment was achieved in 21/21 cases included in the study. No signs of retinal or RPE toxicity were detected and WF-OCT performed in the areas of VCRs removal revealed an intact inner retinal architecture in the majority of eyes, with minor and localized inner retinal indentations in 4 cases. Conclusions: VCRs visualization and removal using TA and EDDS appears to be safe, with no retinal toxicity and very limited and circumscribed mechanical trauma. This approach may contribute to reducing the risk of postoperative PVR.
Related Topics
Concepts
Retinal
Vitrectomy
Pars plana
Medicine
Ophthalmology
Retina
Triamcinolone acetonide
Proliferative vitreoretinopathy
Retinal detachment
Retinal pigment epithelium
Visual acuity
Biology
Neuroscience
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/diagnostics15151854
- https://www.mdpi.com/2075-4418/15/15/1854/pdf?version=1753265974
- OA Status
- gold
- Cited By
- 1
- References
- 49
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4412594303
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4412594303Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/diagnostics15151854Digital Object Identifier
- Title
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Triamcinolone Acetonide-Assisted Visualization and Removal of Vitreous Cortex Remnants in Retinal Detachment: A Prospective Cohort StudyWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-07-23Full publication date if available
- Authors
-
Francesco Faraldi, Carlo Lavia, Daniela Bacherini, Clara Rizzo, Maria Cristina Savastano, Marco Nassisi, Mariantonia Ferrara, Mary Romano, Stanislao RizzoList of authors in order
- Landing page
-
https://doi.org/10.3390/diagnostics15151854Publisher landing page
- PDF URL
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https://www.mdpi.com/2075-4418/15/15/1854/pdf?version=1753265974Direct link to full text PDF
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://www.mdpi.com/2075-4418/15/15/1854/pdf?version=1753265974Direct OA link when available
- Concepts
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Retinal, Vitrectomy, Pars plana, Medicine, Ophthalmology, Retina, Triamcinolone acetonide, Proliferative vitreoretinopathy, Retinal detachment, Retinal pigment epithelium, Visual acuity, Biology, NeuroscienceTop concepts (fields/topics) attached by OpenAlex
- Cited by
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1Total citation count in OpenAlex
- Citations by year (recent)
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2025: 1Per-year citation counts (last 5 years)
- References (count)
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49Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| corresponding_institution_ids | https://openalex.org/I4210129188 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.6499999761581421 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.89801206 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |