Tumores estromales gastrointestinales (GIST) gástricos, serie de casos Article Swipe
YOU?
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· 2021
· Open Access
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· DOI: https://doi.org/10.22516/25007440.569
Introducción: los tumores estromales gastrointestinales (GIST) representan hasta el 2 % de las neoplasias gastrointestinales, estos aparecen en cualquier parte del tracto gastrointestinal y son encontrados más frecuentemente en el estómago (60 %). El diagnóstico se realiza por la expresión de un receptor de factor de crecimiento de tirosina-cinasa, antígeno de diferenciación (CD) 117, lo que lo diferencia de los otros tumores mesenquimales como leiomiomas, leiomiosarcomas, leiomioblastomas y tumores neurogénicos, que no expresan esta proteína. Objetivo: el objetivo de nuestro trabajo es caracterizar los GIST de localización gástrica con respecto a su presentación clínica, diagnóstico, manejo, recurrencia y supervivencia. Métodos: se trata de un estudio observacional, retrospectivo basado en una serie de casos. Se realizó una extracción de la información por medio de la revisión de las historias clínicas de los pacientes con GIST gástricos en un centro oncológico de Bogotá entre enero de 2005 y diciembre de 2015. La información recolectada incluyó tipo de manejo y abordaje quirúrgico, localización, tamaño, índice mitótico y clasificación de riesgo. Resultados: se encontraron 31 pacientes con diagnóstico de GIST gástrico. La edad media fue de 62,3 años, con una mediana de 61 años. De los 31 pacientes, 18 fueron mujeres y 13 hombres. El tiempo de seguimiento estuvo entre un mínimo de 2,4 meses y un máximo de 214 meses, La mediana de seguimiento fue de 36 meses. Conclusiones: los GIST son tumores potencialmente malignos, y el de localización gástrica es el más frecuente. El diagnóstico y tratamiento dependen de su tamaño y localización dentro del estómago. El manejo es variado y consiste en la resección quirúrgica, en la que los procedimientos son mínimamente invasivos, en combinación con la endoscopia, que son una buena alternativa al tratamiento abierto hasta que haya necesidad de terapia sistémica.
Related Topics
- Type
- article
- Language
- es
- Landing Page
- https://doi.org/10.22516/25007440.569
- https://revistagastrocol.com/index.php/rcg/article/download/569/1136
- OA Status
- diamond
- Cited By
- 3
- References
- 25
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3174307266
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3174307266Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.22516/25007440.569Digital Object Identifier
- Title
-
Tumores estromales gastrointestinales (GIST) gástricos, serie de casosWork title
- Type
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articleOpenAlex work type
- Language
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esPrimary language
- Publication year
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2021Year of publication
- Publication date
-
2021-06-29Full publication date if available
- Authors
-
Ricardo Oliveros Wilches, Raúl Eduardo Pinilla Morales, Ricardo Sánchez, Haylmanrth Fernán Contreras RamosList of authors in order
- Landing page
-
https://doi.org/10.22516/25007440.569Publisher landing page
- PDF URL
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https://revistagastrocol.com/index.php/rcg/article/download/569/1136Direct link to full text PDF
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YesWhether a free full text is available
- OA status
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diamondOpen access status per OpenAlex
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https://revistagastrocol.com/index.php/rcg/article/download/569/1136Direct OA link when available
- Concepts
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GiST, Medicine, Internal medicine, Stromal cellTop concepts (fields/topics) attached by OpenAlex
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3Total citation count in OpenAlex
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2024: 1, 2023: 1, 2022: 1Per-year citation counts (last 5 years)
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25Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.diferencia | 57 |
| abstract_inverted_index.estromales | 3 |
| abstract_inverted_index.estómago. | 253 |
| abstract_inverted_index.expresión | 39 |
| abstract_inverted_index.frecuente. | 240 |
| abstract_inverted_index.gástrico. | 176 |
| abstract_inverted_index.gástricos | 134 |
| abstract_inverted_index.invasivos, | 271 |
| abstract_inverted_index.neoplasias | 13 |
| abstract_inverted_index.pacientes, | 193 |
| abstract_inverted_index.resección | 262 |
| abstract_inverted_index.Resultados: | 167 |
| abstract_inverted_index.alternativa | 281 |
| abstract_inverted_index.crecimiento | 46 |
| abstract_inverted_index.encontrados | 25 |
| abstract_inverted_index.encontraron | 169 |
| abstract_inverted_index.endoscopia, | 276 |
| abstract_inverted_index.extracción | 116 |
| abstract_inverted_index.leiomiomas, | 64 |
| abstract_inverted_index.oncológico | 138 |
| abstract_inverted_index.recolectada | 151 |
| abstract_inverted_index.recurrencia | 96 |
| abstract_inverted_index.representan | 6 |
| abstract_inverted_index.seguimiento | 203, 220 |
| abstract_inverted_index.sistémica. | 291 |
| abstract_inverted_index.tratamiento | 244, 283 |
| abstract_inverted_index.caracterizar | 82 |
| abstract_inverted_index.combinación | 273 |
| abstract_inverted_index.diagnóstico | 34, 173, 242 |
| abstract_inverted_index.información | 119, 150 |
| abstract_inverted_index.meses.
 | 224 |
| abstract_inverted_index.mínimamente | 270 |
| abstract_inverted_index.quirúrgica, | 263 |
| abstract_inverted_index.quirúrgico, | 158 |
| abstract_inverted_index.Conclusiones: | 225 |
| abstract_inverted_index.diagnóstico, | 94 |
| abstract_inverted_index.localización | 86, 235, 250 |
| abstract_inverted_index.mesenquimales | 62 |
| abstract_inverted_index.presentación | 92 |
| abstract_inverted_index.retrospectivo | 106 |
| abstract_inverted_index.riesgo.
 | 166 |
| abstract_inverted_index.Introducción: | 0 |
| abstract_inverted_index.clasificación | 164 |
| abstract_inverted_index.frecuentemente | 27 |
| abstract_inverted_index.localización, | 159 |
| abstract_inverted_index.neurogénicos, | 69 |
| abstract_inverted_index.observacional, | 105 |
| abstract_inverted_index.potencialmente | 230 |
| abstract_inverted_index.procedimientos | 268 |
| abstract_inverted_index.diferenciación | 51 |
| abstract_inverted_index.gastrointestinal | 22 |
| abstract_inverted_index.leiomioblastomas | 66 |
| abstract_inverted_index.leiomiosarcomas, | 65 |
| abstract_inverted_index.proteína.
 | 74 |
| abstract_inverted_index.tirosina-cinasa, | 48 |
| abstract_inverted_index.gastrointestinales | 4 |
| abstract_inverted_index.gastrointestinales, | 14 |
| abstract_inverted_index.supervivencia.
 | 98 |
| cited_by_percentile_year.max | 94 |
| cited_by_percentile_year.min | 89 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 4 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.800000011920929 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.64604926 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |