Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms Article Swipe
Lisa Bleul
,
Patrice François
,
Christiane Wolz
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.3390/genes13010034
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.3390/genes13010034
Staphylococcus aureus encodes 16 two-component systems (TCSs) that enable the bacteria to sense and respond to changing environmental conditions. Considering the function of these TCSs in bacterial survival and their potential role as drug targets, it is important to understand the exact mechanisms underlying signal perception. The differences between the sensing of appropriate signals and the transcriptional activation of the TCS system are often not well described, and the signaling mechanisms are only partially understood. Here, we review present insights into which signals are sensed by histidine kinases in S. aureus to promote appropriate gene expression in response to diverse environmental challenges.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.3390/genes13010034
- https://www.mdpi.com/2073-4425/13/1/34/pdf?version=1640256047
- OA Status
- gold
- Cited By
- 71
- References
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- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
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https://openalex.org/W4200021762Canonical identifier for this work in OpenAlex
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https://doi.org/10.3390/genes13010034Digital Object Identifier
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Two-Component Systems of S. aureus: Signaling and Sensing MechanismsWork title
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reviewOpenAlex work type
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enPrimary language
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2021Year of publication
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2021-12-23Full publication date if available
- Authors
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Lisa Bleul, Patrice François, Christiane WolzList of authors in order
- Landing page
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https://doi.org/10.3390/genes13010034Publisher landing page
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https://www.mdpi.com/2073-4425/13/1/34/pdf?version=1640256047Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.mdpi.com/2073-4425/13/1/34/pdf?version=1640256047Direct OA link when available
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Component (thermodynamics), Staphylococcus aureus, Computational biology, Biology, Cell biology, Computer science, Genetics, Bacteria, Physics, ThermodynamicsTop concepts (fields/topics) attached by OpenAlex
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71Total citation count in OpenAlex
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2025: 26, 2024: 22, 2023: 15, 2022: 8Per-year citation counts (last 5 years)
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152Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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