Ultrafast polarization bio-imaging based on coherent detection and time-stretch techniques Article Swipe
Lu Song
,
Yuanhua Feng
,
Xiaojie Guo
,
Yuecheng Shen
,
Daixuan Wu
,
Zhenhua Wu
,
Congran Zhou
,
Linyan Zhu
,
Shecheng Gao
,
Weiping Liu
,
Xuming Zhang
,
Zhaohui Li
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1364/boe.9.006556
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1364/boe.9.006556
Optical polarization imaging has played an important role in many biological and biomedical applications, as it provides a label-free and non-invasive detection scheme to reveal the polarization information of optical rotation, birefringence, and photoelasticity distribution inherent in biological samples. However, the imaging speeds of the previously demonstrated polarization imaging techniques were often limited by the slow frame rates of the arrayed imaging detectors, which usually run at frame rates of several hundred hertz. By combining the optical coherent detection of orthogonal polarizations and the optical time-stretch imaging technique, we achieved ultrafast polarization bio-imaging at an extremely fast record line scanning rate up to 100 MHz without averaging. We experimentally demonstrated the superior performance of our method by imaging three slices of different kinds of biological samples with the retrieved Jones matrix and polarization-sensitive information including birefringence and diattenuation. The proposed system in this paper may find potential applications for ultrafast polarization dynamics in living samples or some other advanced biomedical research.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1364/boe.9.006556
- OA Status
- gold
- Cited By
- 12
- References
- 35
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2903423840
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2903423840Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1364/boe.9.006556Digital Object Identifier
- Title
-
Ultrafast polarization bio-imaging based on coherent detection and time-stretch techniquesWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
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2018Year of publication
- Publication date
-
2018-11-29Full publication date if available
- Authors
-
Lu Song, Yuanhua Feng, Xiaojie Guo, Yuecheng Shen, Daixuan Wu, Zhenhua Wu, Congran Zhou, Linyan Zhu, Shecheng Gao, Weiping Liu, Xuming Zhang, Zhaohui LiList of authors in order
- Landing page
-
https://doi.org/10.1364/boe.9.006556Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1364/boe.9.006556Direct OA link when available
- Concepts
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Ultrashort pulse, Optics, Optical imaging, Polarization (electrochemistry), Optical coherence tomography, Medical imaging, Ultrafast optics, Biomedical engineering, Materials science, Computer science, Medicine, Physics, Laser, Artificial intelligence, Chemistry, Physical chemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
12Total citation count in OpenAlex
- Citations by year (recent)
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2025: 1, 2024: 2, 2023: 1, 2022: 4, 2021: 3Per-year citation counts (last 5 years)
- References (count)
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35Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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