Unraveling atomic complexity from frozen samples Article Swipe
Yasmeen N. Ruma
,
Brent L. Nannenga
,
Tamir Gonen
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1063/4.0000303
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1063/4.0000303
Cryo-electron microscopy (cryo-EM) is a significant driver of recent advances in structural biology. Cryo-EM is comprised of several distinct and complementary methods, which include single particle analysis, cryo-electron tomography, and microcrystal electron diffraction. In this Perspective, we will briefly discuss the different branches of cryo-EM in structural biology and the current challenges in these areas.
Related Topics
Concepts
Cryo-electron microscopy
Cryo-electron tomography
Structural biology
Single particle analysis
Electron microscope
Electron tomography
Nanotechnology
Materials science
Biophysics
Chemistry
Physics
Biology
Tomography
Optics
Cell biology
Scanning transmission electron microscopy
Organic chemistry
Aerosol
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1063/4.0000303
- OA Status
- gold
- References
- 142
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4409580554
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4409580554Canonical identifier for this work in OpenAlex
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https://doi.org/10.1063/4.0000303Digital Object Identifier
- Title
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Unraveling atomic complexity from frozen samplesWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-03-01Full publication date if available
- Authors
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Yasmeen N. Ruma, Brent L. Nannenga, Tamir GonenList of authors in order
- Landing page
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https://doi.org/10.1063/4.0000303Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
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https://doi.org/10.1063/4.0000303Direct OA link when available
- Concepts
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Cryo-electron microscopy, Cryo-electron tomography, Structural biology, Single particle analysis, Electron microscope, Electron tomography, Nanotechnology, Materials science, Biophysics, Chemistry, Physics, Biology, Tomography, Optics, Cell biology, Scanning transmission electron microscopy, Organic chemistry, AerosolTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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142Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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