Unraveling osteogenesis mechanisms of the empowered VitaFlux adaptive regeneration biomaterials for bone tissue engineering: Insights into the role of BBGs/BSBGs Article Swipe

View

Xian Li , Kun Su , Limin Zhao , Hao Zhang , Qiang Yang , Ping Du , Xiaofeng Chen , Haobo Pan ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1016/j.bioactmat.2025.03.006

Related Topics

Regeneration (Biology)

Tissue Engineering

Materials Science

Biomedical Engineering

Concepts

Regeneration (biology) Tissue engineering Materials science Biomedical engineering Bone formation Cell biology Engineering Medicine Biology Endocrinology

Metadata

Type: review
Language: en
Landing Page: https://doi.org/10.1016/j.bioactmat.2025.03.006
OA Status: gold
Cited By: 4
References: 137
Related Works: 10
OpenAlex ID: https://openalex.org/W4408365725

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W4408365725

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.1016/j.bioactmat.2025.03.006

Digital Object Identifier
Title: Unraveling osteogenesis mechanisms of the empowered VitaFlux adaptive regeneration biomaterials for bone tissue engineering: Insights into the role of BBGs/BSBGs

Work title
Type: review

OpenAlex work type
Language: en

Primary language
Publication year: 2025

Year of publication
Publication date: 2025-03-12

Full publication date if available
Authors: Xian Li, Kun Su, Limin Zhao, Hao Zhang, Qiang Yang, Ping Du, Xiaofeng Chen, Haobo Pan

List of authors in order
Landing page: https://doi.org/10.1016/j.bioactmat.2025.03.006

Publisher landing page
Open access: Yes

Whether a free full text is available
OA status: gold

Open access status per OpenAlex
OA URL: https://doi.org/10.1016/j.bioactmat.2025.03.006

Direct OA link when available
Concepts: Regeneration (biology), Tissue engineering, Materials science, Biomedical engineering, Bone formation, Cell biology, Engineering, Medicine, Biology, Endocrinology

Top concepts (fields/topics) attached by OpenAlex
Cited by: 4

Total citation count in OpenAlex
Citations by year (recent): 2025: 4

Per-year citation counts (last 5 years)
References (count): 137

Number of works referenced by this work
Related works (count): 10

Other works algorithmically related by OpenAlex

Full payload

id	https://openalex.org/W4408365725
doi	https://doi.org/10.1016/j.bioactmat.2025.03.006
ids.doi	https://doi.org/10.1016/j.bioactmat.2025.03.006
ids.pmid	https://pubmed.ncbi.nlm.nih.gov/40130079
ids.openalex	https://openalex.org/W4408365725
fwci	7.97144723
type	review
title	Unraveling osteogenesis mechanisms of the empowered VitaFlux adaptive regeneration biomaterials for bone tissue engineering: Insights into the role of BBGs/BSBGs
biblio.issue
biblio.volume	49
biblio.last_page	290
biblio.first_page	271
topics[0].id	https://openalex.org/T10059
topics[0].field.id	https://openalex.org/fields/22
topics[0].field.display_name	Engineering
topics[0].score	0.9997000098228455
topics[0].domain.id	https://openalex.org/domains/3
topics[0].domain.display_name	Physical Sciences
topics[0].subfield.id	https://openalex.org/subfields/2204
topics[0].subfield.display_name	Biomedical Engineering
topics[0].display_name	Bone Tissue Engineering Materials
topics[1].id	https://openalex.org/T10512
topics[1].field.id	https://openalex.org/fields/27
topics[1].field.display_name	Medicine
topics[1].score	0.9775000214576721
topics[1].domain.id	https://openalex.org/domains/4
topics[1].domain.display_name	Health Sciences
topics[1].subfield.id	https://openalex.org/subfields/2746
topics[1].subfield.display_name	Surgery
topics[1].display_name	Orthopaedic implants and arthroplasty
topics[2].id	https://openalex.org/T12110
topics[2].field.id	https://openalex.org/fields/27
topics[2].field.display_name	Medicine
topics[2].score	0.9753999710083008
topics[2].domain.id	https://openalex.org/domains/4
topics[2].domain.display_name	Health Sciences
topics[2].subfield.id	https://openalex.org/subfields/2745
topics[2].subfield.display_name	Rheumatology
topics[2].display_name	Bone and Dental Protein Studies
is_xpac	False
apc_list.value	1500
apc_list.currency	USD
apc_list.value_usd	1500
apc_paid.value	1500
apc_paid.currency	USD
apc_paid.value_usd	1500
concepts[0].id	https://openalex.org/C171056886
concepts[0].level	2
concepts[0].score	0.6599697470664978
concepts[0].wikidata	https://www.wikidata.org/wiki/Q193119
concepts[0].display_name	Regeneration (biology)
concepts[1].id	https://openalex.org/C49892992
concepts[1].level	2
concepts[1].score	0.5368777513504028
concepts[1].wikidata	https://www.wikidata.org/wiki/Q1540285
concepts[1].display_name	Tissue engineering
concepts[2].id	https://openalex.org/C192562407
concepts[2].level	0
concepts[2].score	0.5176054239273071
concepts[2].wikidata	https://www.wikidata.org/wiki/Q228736
concepts[2].display_name	Materials science
concepts[3].id	https://openalex.org/C136229726
concepts[3].level	1
concepts[3].score	0.45467883348464966
concepts[3].wikidata	https://www.wikidata.org/wiki/Q327092
concepts[3].display_name	Biomedical engineering
concepts[4].id	https://openalex.org/C2993291840
concepts[4].level	2
concepts[4].score	0.4441814422607422
concepts[4].wikidata	https://www.wikidata.org/wiki/Q1121544
concepts[4].display_name	Bone formation
concepts[5].id	https://openalex.org/C95444343
concepts[5].level	1
concepts[5].score	0.2816725969314575
concepts[5].wikidata	https://www.wikidata.org/wiki/Q7141
concepts[5].display_name	Cell biology
concepts[6].id	https://openalex.org/C127413603
concepts[6].level	0
concepts[6].score	0.15063849091529846
concepts[6].wikidata	https://www.wikidata.org/wiki/Q11023
concepts[6].display_name	Engineering
concepts[7].id	https://openalex.org/C71924100
concepts[7].level	0
concepts[7].score	0.09236794710159302
concepts[7].wikidata	https://www.wikidata.org/wiki/Q11190
concepts[7].display_name	Medicine
concepts[8].id	https://openalex.org/C86803240
concepts[8].level	0
concepts[8].score	0.0792233943939209
concepts[8].wikidata	https://www.wikidata.org/wiki/Q420
concepts[8].display_name	Biology
concepts[9].id	https://openalex.org/C134018914
concepts[9].level	1
concepts[9].score	0.0
concepts[9].wikidata	https://www.wikidata.org/wiki/Q162606
concepts[9].display_name	Endocrinology
keywords[0].id	https://openalex.org/keywords/regeneration
keywords[0].score	0.6599697470664978
keywords[0].display_name	Regeneration (biology)
keywords[1].id	https://openalex.org/keywords/tissue-engineering
keywords[1].score	0.5368777513504028
keywords[1].display_name	Tissue engineering
keywords[2].id	https://openalex.org/keywords/materials-science
keywords[2].score	0.5176054239273071
keywords[2].display_name	Materials science
keywords[3].id	https://openalex.org/keywords/biomedical-engineering
keywords[3].score	0.45467883348464966
keywords[3].display_name	Biomedical engineering
keywords[4].id	https://openalex.org/keywords/bone-formation
keywords[4].score	0.4441814422607422
keywords[4].display_name	Bone formation
keywords[5].id	https://openalex.org/keywords/cell-biology
keywords[5].score	0.2816725969314575
keywords[5].display_name	Cell biology
keywords[6].id	https://openalex.org/keywords/engineering
keywords[6].score	0.15063849091529846
keywords[6].display_name	Engineering
keywords[7].id	https://openalex.org/keywords/medicine
keywords[7].score	0.09236794710159302
keywords[7].display_name	Medicine
keywords[8].id	https://openalex.org/keywords/biology
keywords[8].score	0.0792233943939209
keywords[8].display_name	Biology
language	en
locations[0].id	doi:10.1016/j.bioactmat.2025.03.006
locations[0].is_oa	True
locations[0].source.id	https://openalex.org/S2898508902
locations[0].source.issn	2097-1192, 2452-199X
locations[0].source.type	journal
locations[0].source.is_oa	True
locations[0].source.issn_l	2097-1192
locations[0].source.is_core	True
locations[0].source.is_in_doaj	True
locations[0].source.display_name	Bioactive Materials
locations[0].source.host_organization	https://openalex.org/P4310320990
locations[0].source.host_organization_name	Elsevier BV
locations[0].source.host_organization_lineage	https://openalex.org/P4310320990
locations[0].license
locations[0].pdf_url
locations[0].version	publishedVersion
locations[0].raw_type	journal-article
locations[0].license_id
locations[0].is_accepted	True
locations[0].is_published	True
locations[0].raw_source_name	Bioactive Materials
locations[0].landing_page_url	https://doi.org/10.1016/j.bioactmat.2025.03.006
locations[1].id	pmid:40130079
locations[1].is_oa	False
locations[1].source.id	https://openalex.org/S4306525036
locations[1].source.issn
locations[1].source.type	repository
locations[1].source.is_oa	False
locations[1].source.issn_l
locations[1].source.is_core	False
locations[1].source.is_in_doaj	False
locations[1].source.display_name	PubMed
locations[1].source.host_organization	https://openalex.org/I1299303238
locations[1].source.host_organization_name	National Institutes of Health
locations[1].source.host_organization_lineage	https://openalex.org/I1299303238
locations[1].license
locations[1].pdf_url
locations[1].version	publishedVersion
locations[1].raw_type
locations[1].license_id
locations[1].is_accepted	True
locations[1].is_published	True
locations[1].raw_source_name	Bioactive materials
locations[1].landing_page_url	https://pubmed.ncbi.nlm.nih.gov/40130079
locations[2].id	pmh:oai:europepmc.org:10744709
locations[2].is_oa	True
locations[2].source.id	https://openalex.org/S4306400806
locations[2].source.issn
locations[2].source.type	repository
locations[2].source.is_oa	False
locations[2].source.issn_l
locations[2].source.is_core	False
locations[2].source.is_in_doaj	False
locations[2].source.display_name	Europe PMC (PubMed Central)
locations[2].source.host_organization	https://openalex.org/I1303153112
locations[2].source.host_organization_name	European Bioinformatics Institute
locations[2].source.host_organization_lineage	https://openalex.org/I1303153112
locations[2].license	other-oa
locations[2].pdf_url
locations[2].version	submittedVersion
locations[2].raw_type	Text
locations[2].license_id	https://openalex.org/licenses/other-oa
locations[2].is_accepted	False
locations[2].is_published	False
locations[2].raw_source_name
locations[2].landing_page_url	https://www.ncbi.nlm.nih.gov/pmc/articles/11932761
indexed_in	crossref, doaj, pubmed
authorships[0].author.id	https://openalex.org/A5100727620
authorships[0].author.orcid	https://orcid.org/0009-0002-8129-3812
authorships[0].author.display_name	Xian Li
authorships[0].countries	CN
authorships[0].affiliations[0].institution_ids	https://openalex.org/I19820366, https://openalex.org/I4210145761
authorships[0].affiliations[0].raw_affiliation_string	Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
authorships[0].institutions[0].id	https://openalex.org/I19820366
authorships[0].institutions[0].ror	https://ror.org/034t30j35
authorships[0].institutions[0].type	government
authorships[0].institutions[0].lineage	https://openalex.org/I19820366
authorships[0].institutions[0].country_code	CN
authorships[0].institutions[0].display_name	Chinese Academy of Sciences
authorships[0].institutions[1].id	https://openalex.org/I4210145761
authorships[0].institutions[1].ror	https://ror.org/04gh4er46
authorships[0].institutions[1].type	facility
authorships[0].institutions[1].lineage	https://openalex.org/I19820366, https://openalex.org/I4210145761
authorships[0].institutions[1].country_code	CN
authorships[0].institutions[1].display_name	Shenzhen Institutes of Advanced Technology
authorships[0].author_position	first
authorships[0].raw_author_name	Xian Li
authorships[0].is_corresponding	False
authorships[0].raw_affiliation_strings	Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
authorships[1].author.id	https://openalex.org/A5057616985
authorships[1].author.orcid	https://orcid.org/0000-0002-5374-958X
authorships[1].author.display_name	Kun Su
authorships[1].countries	CN
authorships[1].affiliations[0].institution_ids	https://openalex.org/I19820366, https://openalex.org/I4210145761
authorships[1].affiliations[0].raw_affiliation_string	Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
authorships[1].institutions[0].id	https://openalex.org/I19820366
authorships[1].institutions[0].ror	https://ror.org/034t30j35
authorships[1].institutions[0].type	government
authorships[1].institutions[0].lineage	https://openalex.org/I19820366
authorships[1].institutions[0].country_code	CN
authorships[1].institutions[0].display_name	Chinese Academy of Sciences
authorships[1].institutions[1].id	https://openalex.org/I4210145761
authorships[1].institutions[1].ror	https://ror.org/04gh4er46
authorships[1].institutions[1].type	facility
authorships[1].institutions[1].lineage	https://openalex.org/I19820366, https://openalex.org/I4210145761
authorships[1].institutions[1].country_code	CN
authorships[1].institutions[1].display_name	Shenzhen Institutes of Advanced Technology
authorships[1].author_position	middle
authorships[1].raw_author_name	Kun Su
authorships[1].is_corresponding	False
authorships[1].raw_affiliation_strings	Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
authorships[2].author.id	https://openalex.org/A5112533571
authorships[2].author.orcid
authorships[2].author.display_name	Limin Zhao
authorships[2].countries	CN
authorships[2].affiliations[0].institution_ids	https://openalex.org/I4210086166
authorships[2].affiliations[0].raw_affiliation_string	Shenzhen Healthemes Biotechnology Co. Ltd, Shenzhen, 518102, PR China.
authorships[2].affiliations[1].institution_ids	https://openalex.org/I4210092654
authorships[2].affiliations[1].raw_affiliation_string	Geriatric Medicine Department and General Medicine Department, Shenzhen Longhua District Central Hospital, Shenzhen, 518000, PR China.
authorships[2].institutions[0].id	https://openalex.org/I4210092654
authorships[2].institutions[0].ror	https://ror.org/00j5y7k81
authorships[2].institutions[0].type	healthcare
authorships[2].institutions[0].lineage	https://openalex.org/I4210092654
authorships[2].institutions[0].country_code	CN
authorships[2].institutions[0].display_name	Longgang Central Hospital
authorships[2].institutions[1].id	https://openalex.org/I4210086166
authorships[2].institutions[1].ror	https://ror.org/00pxc7m47
authorships[2].institutions[1].type	company
authorships[2].institutions[1].lineage	https://openalex.org/I4210086166
authorships[2].institutions[1].country_code	CN
authorships[2].institutions[1].display_name	Shenzhen Bioeasy Biotechnology (China)
authorships[2].author_position	middle
authorships[2].raw_author_name	Limin Zhao
authorships[2].is_corresponding	False
authorships[2].raw_affiliation_strings	Geriatric Medicine Department and General Medicine Department, Shenzhen Longhua District Central Hospital, Shenzhen, 518000, PR China., Shenzhen Healthemes Biotechnology Co. Ltd, Shenzhen, 518102, PR China.
authorships[3].author.id	https://openalex.org/A5100396901
authorships[3].author.orcid	https://orcid.org/0000-0002-3782-6282
authorships[3].author.display_name	Hao Zhang
authorships[3].countries	CN
authorships[3].affiliations[0].institution_ids	https://openalex.org/I19820366, https://openalex.org/I4210145761
authorships[3].affiliations[0].raw_affiliation_string	Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
authorships[3].institutions[0].id	https://openalex.org/I19820366
authorships[3].institutions[0].ror	https://ror.org/034t30j35
authorships[3].institutions[0].type	government
authorships[3].institutions[0].lineage	https://openalex.org/I19820366
authorships[3].institutions[0].country_code	CN
authorships[3].institutions[0].display_name	Chinese Academy of Sciences
authorships[3].institutions[1].id	https://openalex.org/I4210145761
authorships[3].institutions[1].ror	https://ror.org/04gh4er46
authorships[3].institutions[1].type	facility
authorships[3].institutions[1].lineage	https://openalex.org/I19820366, https://openalex.org/I4210145761
authorships[3].institutions[1].country_code	CN
authorships[3].institutions[1].display_name	Shenzhen Institutes of Advanced Technology
authorships[3].author_position	middle
authorships[3].raw_author_name	Hao Zhang
authorships[3].is_corresponding	False
authorships[3].raw_affiliation_strings	Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
authorships[4].author.id	https://openalex.org/A5041210716
authorships[4].author.orcid	https://orcid.org/0000-0003-3762-5015
authorships[4].author.display_name	Qiang Yang
authorships[4].countries	CN
authorships[4].affiliations[0].institution_ids	https://openalex.org/I162868743, https://openalex.org/I4210142182
authorships[4].affiliations[0].raw_affiliation_string	Department of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, 300211, PR China.
authorships[4].institutions[0].id	https://openalex.org/I4210142182
authorships[4].institutions[0].ror	https://ror.org/04j9yn198
authorships[4].institutions[0].type	healthcare
authorships[4].institutions[0].lineage	https://openalex.org/I4210142182
authorships[4].institutions[0].country_code	CN
authorships[4].institutions[0].display_name	Tianjin Hospital
authorships[4].institutions[1].id	https://openalex.org/I162868743
authorships[4].institutions[1].ror	https://ror.org/012tb2g32
authorships[4].institutions[1].type	education
authorships[4].institutions[1].lineage	https://openalex.org/I162868743
authorships[4].institutions[1].country_code	CN
authorships[4].institutions[1].display_name	Tianjin University
authorships[4].author_position	middle
authorships[4].raw_author_name	Qiang Yang
authorships[4].is_corresponding	False
authorships[4].raw_affiliation_strings	Department of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, 300211, PR China.
authorships[5].author.id	https://openalex.org/A5009035703
authorships[5].author.orcid	https://orcid.org/0000-0002-8662-3705
authorships[5].author.display_name	Ping Du
authorships[5].countries	CN
authorships[5].affiliations[0].institution_ids	https://openalex.org/I19820366, https://openalex.org/I4210145761
authorships[5].affiliations[0].raw_affiliation_string	Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
authorships[5].institutions[0].id	https://openalex.org/I19820366
authorships[5].institutions[0].ror	https://ror.org/034t30j35
authorships[5].institutions[0].type	government
authorships[5].institutions[0].lineage	https://openalex.org/I19820366
authorships[5].institutions[0].country_code	CN
authorships[5].institutions[0].display_name	Chinese Academy of Sciences
authorships[5].institutions[1].id	https://openalex.org/I4210145761
authorships[5].institutions[1].ror	https://ror.org/04gh4er46
authorships[5].institutions[1].type	facility
authorships[5].institutions[1].lineage	https://openalex.org/I19820366, https://openalex.org/I4210145761
authorships[5].institutions[1].country_code	CN
authorships[5].institutions[1].display_name	Shenzhen Institutes of Advanced Technology
authorships[5].author_position	middle
authorships[5].raw_author_name	Ping Du
authorships[5].is_corresponding	False
authorships[5].raw_affiliation_strings	Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
authorships[6].author.id	https://openalex.org/A5100352382
authorships[6].author.orcid	https://orcid.org/0000-0002-3591-8001
authorships[6].author.display_name	Xiaofeng Chen
authorships[6].countries	CN
authorships[6].affiliations[0].institution_ids	https://openalex.org/I14894300
authorships[6].affiliations[0].raw_affiliation_string	School of Medicine, Foshan University, Foshan, 528000, PR China.
authorships[6].affiliations[1].institution_ids	https://openalex.org/I4210133824
authorships[6].affiliations[1].raw_affiliation_string	National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, 510006, PR China.
authorships[6].affiliations[2].institution_ids	https://openalex.org/I90610280
authorships[6].affiliations[2].raw_affiliation_string	Department of Biomedical Engineering, School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, PR China.
authorships[6].institutions[0].id	https://openalex.org/I14894300
authorships[6].institutions[0].ror	https://ror.org/02xvvvp28
authorships[6].institutions[0].type	education
authorships[6].institutions[0].lineage	https://openalex.org/I14894300
authorships[6].institutions[0].country_code	CN
authorships[6].institutions[0].display_name	Foshan University
authorships[6].institutions[1].id	https://openalex.org/I4210133824
authorships[6].institutions[1].ror	https://ror.org/03c6k3q87
authorships[6].institutions[1].type	facility
authorships[6].institutions[1].lineage	https://openalex.org/I4210098389, https://openalex.org/I4210127390, https://openalex.org/I4210133824
authorships[6].institutions[1].country_code	CN
authorships[6].institutions[1].display_name	National Research Center for Rehabilitation Technical Aids
authorships[6].institutions[2].id	https://openalex.org/I90610280
authorships[6].institutions[2].ror	https://ror.org/0530pts50
authorships[6].institutions[2].type	education
authorships[6].institutions[2].lineage	https://openalex.org/I90610280
authorships[6].institutions[2].country_code	CN
authorships[6].institutions[2].display_name	South China University of Technology
authorships[6].author_position	middle
authorships[6].raw_author_name	Xiaofeng Chen
authorships[6].is_corresponding	False
authorships[6].raw_affiliation_strings	Department of Biomedical Engineering, School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, PR China., National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, 510006, PR China., School of Medicine, Foshan University, Foshan, 528000, PR China.
authorships[7].author.id	https://openalex.org/A5112307515
authorships[7].author.orcid	https://orcid.org/0000-0002-8775-8572
authorships[7].author.display_name	Haobo Pan
authorships[7].countries	CN
authorships[7].affiliations[0].institution_ids	https://openalex.org/I4210086166
authorships[7].affiliations[0].raw_affiliation_string	Shenzhen Healthemes Biotechnology Co. Ltd, Shenzhen, 518102, PR China.
authorships[7].affiliations[1].institution_ids	https://openalex.org/I19820366, https://openalex.org/I4210145761
authorships[7].affiliations[1].raw_affiliation_string	Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
authorships[7].institutions[0].id	https://openalex.org/I19820366
authorships[7].institutions[0].ror	https://ror.org/034t30j35
authorships[7].institutions[0].type	government
authorships[7].institutions[0].lineage	https://openalex.org/I19820366
authorships[7].institutions[0].country_code	CN
authorships[7].institutions[0].display_name	Chinese Academy of Sciences
authorships[7].institutions[1].id	https://openalex.org/I4210086166
authorships[7].institutions[1].ror	https://ror.org/00pxc7m47
authorships[7].institutions[1].type	company
authorships[7].institutions[1].lineage	https://openalex.org/I4210086166
authorships[7].institutions[1].country_code	CN
authorships[7].institutions[1].display_name	Shenzhen Bioeasy Biotechnology (China)
authorships[7].institutions[2].id	https://openalex.org/I4210145761
authorships[7].institutions[2].ror	https://ror.org/04gh4er46
authorships[7].institutions[2].type	facility
authorships[7].institutions[2].lineage	https://openalex.org/I19820366, https://openalex.org/I4210145761
authorships[7].institutions[2].country_code	CN
authorships[7].institutions[2].display_name	Shenzhen Institutes of Advanced Technology
authorships[7].author_position	last
authorships[7].raw_author_name	Haobo Pan
authorships[7].is_corresponding	False
authorships[7].raw_affiliation_strings	Shenzhen Healthemes Biotechnology Co. Ltd, Shenzhen, 518102, PR China., Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
has_content.pdf	False
has_content.grobid_xml	False
is_paratext	False
open_access.is_oa	True
open_access.oa_url	https://doi.org/10.1016/j.bioactmat.2025.03.006
open_access.oa_status	gold
open_access.any_repository_has_fulltext	False
created_date	2025-10-10T00:00:00
display_name	Unraveling osteogenesis mechanisms of the empowered VitaFlux adaptive regeneration biomaterials for bone tissue engineering: Insights into the role of BBGs/BSBGs
has_fulltext	False
is_retracted	False
updated_date	2025-11-06T03:46:38.306776
primary_topic.id	https://openalex.org/T10059
primary_topic.field.id	https://openalex.org/fields/22
primary_topic.field.display_name	Engineering
primary_topic.score	0.9997000098228455
primary_topic.domain.id	https://openalex.org/domains/3
primary_topic.domain.display_name	Physical Sciences
primary_topic.subfield.id	https://openalex.org/subfields/2204
primary_topic.subfield.display_name	Biomedical Engineering
primary_topic.display_name	Bone Tissue Engineering Materials
related_works	https://openalex.org/W2550159186, https://openalex.org/W2028744988, https://openalex.org/W2089076087, https://openalex.org/W2159546193, https://openalex.org/W2147410376, https://openalex.org/W1574287054, https://openalex.org/W3032399641, https://openalex.org/W1992403567, https://openalex.org/W2014762318, https://openalex.org/W2106408936
cited_by_count	4
counts_by_year[0].year	2025
counts_by_year[0].cited_by_count	4
locations_count	3
best_oa_location.id	doi:10.1016/j.bioactmat.2025.03.006
best_oa_location.is_oa	True
best_oa_location.source.id	https://openalex.org/S2898508902
best_oa_location.source.issn	2097-1192, 2452-199X
best_oa_location.source.type	journal
best_oa_location.source.is_oa	True
best_oa_location.source.issn_l	2097-1192
best_oa_location.source.is_core	True
best_oa_location.source.is_in_doaj	True
best_oa_location.source.display_name	Bioactive Materials
best_oa_location.source.host_organization	https://openalex.org/P4310320990
best_oa_location.source.host_organization_name	Elsevier BV
best_oa_location.source.host_organization_lineage	https://openalex.org/P4310320990
best_oa_location.license
best_oa_location.pdf_url
best_oa_location.version	publishedVersion
best_oa_location.raw_type	journal-article
best_oa_location.license_id
best_oa_location.is_accepted	True
best_oa_location.is_published	True
best_oa_location.raw_source_name	Bioactive Materials
best_oa_location.landing_page_url	https://doi.org/10.1016/j.bioactmat.2025.03.006
primary_location.id	doi:10.1016/j.bioactmat.2025.03.006
primary_location.is_oa	True
primary_location.source.id	https://openalex.org/S2898508902
primary_location.source.issn	2097-1192, 2452-199X
primary_location.source.type	journal
primary_location.source.is_oa	True
primary_location.source.issn_l	2097-1192
primary_location.source.is_core	True
primary_location.source.is_in_doaj	True
primary_location.source.display_name	Bioactive Materials
primary_location.source.host_organization	https://openalex.org/P4310320990
primary_location.source.host_organization_name	Elsevier BV
primary_location.source.host_organization_lineage	https://openalex.org/P4310320990
primary_location.license
primary_location.pdf_url
primary_location.version	publishedVersion
primary_location.raw_type	journal-article
primary_location.license_id
primary_location.is_accepted	True
primary_location.is_published	True
primary_location.raw_source_name	Bioactive Materials
primary_location.landing_page_url	https://doi.org/10.1016/j.bioactmat.2025.03.006
publication_date	2025-03-12
publication_year	2025
referenced_works	https://openalex.org/W2069523649, https://openalex.org/W2043310171, https://openalex.org/W4231181115, https://openalex.org/W2111415695, https://openalex.org/W2062321210, https://openalex.org/W2045532255, https://openalex.org/W2115572590, https://openalex.org/W1995331939, https://openalex.org/W2073489944, https://openalex.org/W1965051878, https://openalex.org/W2050864400, https://openalex.org/W2092507917, https://openalex.org/W2049878676, https://openalex.org/W1976419252, https://openalex.org/W2538332725, https://openalex.org/W2165963658, https://openalex.org/W2620174145, https://openalex.org/W2742109279, https://openalex.org/W2048954481, https://openalex.org/W3047493940, https://openalex.org/W3180325479, https://openalex.org/W2286593632, https://openalex.org/W867046626, https://openalex.org/W2987671024, https://openalex.org/W1983032998, https://openalex.org/W2092398848, https://openalex.org/W2809347907, https://openalex.org/W1982414211, https://openalex.org/W2025963891, https://openalex.org/W2136156566, https://openalex.org/W4313527977, https://openalex.org/W4405640287, https://openalex.org/W6864709020, https://openalex.org/W2797845893, https://openalex.org/W2191583599, https://openalex.org/W4321379014, https://openalex.org/W6864613904, https://openalex.org/W3119056567, https://openalex.org/W2002779831, https://openalex.org/W6640242716, https://openalex.org/W2072207728, https://openalex.org/W4242740909, https://openalex.org/W2021370964, https://openalex.org/W2128360354, https://openalex.org/W3023177398, https://openalex.org/W2626681506, https://openalex.org/W2587561586, https://openalex.org/W4297383968, https://openalex.org/W2013647879, https://openalex.org/W3191535358, https://openalex.org/W2116333912, https://openalex.org/W2020339197, https://openalex.org/W2765087739, https://openalex.org/W6677995441, https://openalex.org/W2063082738, https://openalex.org/W2018364671, https://openalex.org/W2060261198, https://openalex.org/W2045571846, https://openalex.org/W2047989797, https://openalex.org/W2341389962, https://openalex.org/W2914117370, https://openalex.org/W2566673774, https://openalex.org/W1988637795, https://openalex.org/W2180963942, https://openalex.org/W2161762920, https://openalex.org/W2132030141, https://openalex.org/W1972983301, https://openalex.org/W2170619852, https://openalex.org/W4225712708, https://openalex.org/W2036669971, https://openalex.org/W2061489090, https://openalex.org/W2922467128, https://openalex.org/W4394849630, https://openalex.org/W2112592146, https://openalex.org/W2889243662, https://openalex.org/W2019196925, https://openalex.org/W6775280278, https://openalex.org/W2998811952, https://openalex.org/W2158186990, https://openalex.org/W2140964710, https://openalex.org/W3207527571, https://openalex.org/W2077129347, https://openalex.org/W3203662469, https://openalex.org/W4327811873, https://openalex.org/W6799800990, https://openalex.org/W1986196165, https://openalex.org/W2909577873, https://openalex.org/W3014897780, https://openalex.org/W4239424738, https://openalex.org/W4308685953, https://openalex.org/W2791013558, https://openalex.org/W1984466107, https://openalex.org/W1988654486, https://openalex.org/W2141459104, https://openalex.org/W6849127658, https://openalex.org/W4398145013, https://openalex.org/W2972875264, https://openalex.org/W2109673760, https://openalex.org/W2945786100, https://openalex.org/W2888236179, https://openalex.org/W2055901626, https://openalex.org/W4213245349, https://openalex.org/W2884099436, https://openalex.org/W2064699790, https://openalex.org/W2024455489, https://openalex.org/W3200041151, https://openalex.org/W4294903940, https://openalex.org/W2606513998, https://openalex.org/W2593816418, https://openalex.org/W6846993489, https://openalex.org/W6850362955, https://openalex.org/W6850183593, https://openalex.org/W4280558908, https://openalex.org/W1986419950, https://openalex.org/W6853526625, https://openalex.org/W2976981435, https://openalex.org/W2190770357, https://openalex.org/W6865096299, https://openalex.org/W2017545194, https://openalex.org/W2765587248, https://openalex.org/W1975729005, https://openalex.org/W2938627826, https://openalex.org/W2999709889, https://openalex.org/W2520738308, https://openalex.org/W2009124035, https://openalex.org/W1985929048, https://openalex.org/W4395089338, https://openalex.org/W4323637192, https://openalex.org/W4313597583, https://openalex.org/W4394764329, https://openalex.org/W2123758480, https://openalex.org/W3193928500, https://openalex.org/W4320912695, https://openalex.org/W4380489163, https://openalex.org/W4308628778, https://openalex.org/W4394766378, https://openalex.org/W1909483178
referenced_works_count	137
abstract_inverted_index
cited_by_percentile_year.max	98
cited_by_percentile_year.min	97
countries_distinct_count	1
institutions_distinct_count	8
sustainable_development_goals[0].id	https://metadata.un.org/sdg/2
sustainable_development_goals[0].score	0.5400000214576721
sustainable_development_goals[0].display_name	Zero hunger
citation_normalized_percentile.value	0.94451671
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	True