Update to: Study Pre-protocol for “BronchStart - The Impact of the COVID-19 Pandemic on the Timing, Age and Severity of Respiratory Syncytial Virus (RSV) Emergency Presentations; a Multi-Centre Prospective Observational Cohort Study” Article Swipe
Thomas Williams
,
Steve Cunningham
,
Simon B. Drysdale
,
Helen Groves
,
Dalia Iskander
,
Xinxue Liu
,
Mark D Lyttle
,
Robin Marlow
,
Abigail Maxwell-Hodkinson
,
Chengetai D Mpamhanga
,
Shaun O’Hagan
,
Ian Sinha
,
Olivia Swann
,
Thomas Waterfield
,
Damian Roland
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.12688/wellcomeopenres.16778.4
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.12688/wellcomeopenres.16778.4
Background In 2021 we launched the BronchStart study, which collected information on 17,899 presentations in children with serious respiratory tract infections following the release of lockdown restrictions. Our study informed the Joint Committee on Vaccination and Immunisation’s decision to recommend the introduction maternal respiratory syncytial virus (RSV) vaccination, which was introduced in the United Kingdom in August/September 2024. Study question We modified our original protocol to conduct a United Kingdom-wide assessment of maternal vaccination against RSV. Methods and likely impact We will conduct a multi-centre study, utilising the PERUKI network used in the original BronchStart study, to assess the effectiveness of maternal vaccination using a test-negative study design. We will gather detailed clinical information on children admitted with bronchiolitis in the post-RSV vaccination era, and understand possible reasons for incomplete vaccine uptake.
Related Topics
Concepts
Observational study
Pandemic
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Medicine
2019-20 coronavirus outbreak
Virology
Protocol (science)
Emergency medicine
Internal medicine
Outbreak
Disease
Alternative medicine
Pathology
Infectious disease (medical specialty)
Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.12688/wellcomeopenres.16778.4
- OA Status
- gold
- References
- 9
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4405526513
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4405526513Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.12688/wellcomeopenres.16778.4Digital Object Identifier
- Title
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Update to: Study Pre-protocol for “BronchStart - The Impact of the COVID-19 Pandemic on the Timing, Age and Severity of Respiratory Syncytial Virus (RSV) Emergency Presentations; a Multi-Centre Prospective Observational Cohort Study”Work title
- Type
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preprintOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-12-18Full publication date if available
- Authors
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Thomas Williams, Steve Cunningham, Simon B. Drysdale, Helen Groves, Dalia Iskander, Xinxue Liu, Mark D Lyttle, Robin Marlow, Abigail Maxwell-Hodkinson, Chengetai D Mpamhanga, Shaun O’Hagan, Ian Sinha, Olivia Swann, Thomas Waterfield, Damian RolandList of authors in order
- Landing page
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https://doi.org/10.12688/wellcomeopenres.16778.4Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.12688/wellcomeopenres.16778.4Direct OA link when available
- Concepts
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Observational study, Pandemic, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Medicine, 2019-20 coronavirus outbreak, Virology, Protocol (science), Emergency medicine, Internal medicine, Outbreak, Disease, Alternative medicine, Pathology, Infectious disease (medical specialty)Top concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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9Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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