Updated progression-free survival and final overall survival with maintenance olaparib plus bevacizumab according to clinical risk in patients with newly diagnosed advanced ovarian cancer in the phase III PAOLA-1/ENGOT-ov25 trial Article Swipe
Domenica Lorusso
,
Marie‐Ange Mouret‐Reynier
,
Philipp Harter
,
Claire Cropet
,
Cristina Caballero
,
P Wolfrum-Ristau
,
Toyomi Satoh
,
Ignace Vergote
,
Gabriella Parma
,
Trine Jakobi Nøttrup
,
Coriolan Lebreton
,
Peter A. Fasching
,
Carmela Pisano
,
Luís Manso
,
Hugues Bourgeois
,
Ingo B. Runnebaum
,
Claudio Zamagni
,
Anne‐Claire Hardy‐Bessard
,
Andreas Schnelzer
,
Michel Fabbro
,
Barbara Schmalfeldt
,
Dominique Berton
,
Antje Belau
,
Jean‐Pierre Lotz
,
Martina Gropp‐Meier
,
Laurence Gladieff
,
Hans‐Joachim Lück
,
Sophie Abadie‐Lacourtoisie
,
Éric Pujade-Lauraine
,
Isabelle Ray‐Coquard
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1136/ijgc-2023-004995
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1136/ijgc-2023-004995
This post hoc analysis indicates that in patients with newly diagnosed advanced HRD-positive ovarian cancer, maintenance olaparib plus bevacizumab should not be limited to those considered at higher risk of disease progression. Five-year progression-free survival rates support long-term remission and suggest an increased potential for cure with particular benefit suggested in lower-risk HRD-positive patients.
Related Topics
Concepts
Medicine
Olaparib
Bevacizumab
Ovarian cancer
Oncology
Internal medicine
Overall survival
Progression-free survival
Maintenance therapy
Cancer
Chemotherapy
Gene
Poly ADP ribose polymerase
Polymerase
Chemistry
Biochemistry
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1136/ijgc-2023-004995
- https://ijgc.bmj.com/content/ijgc/early/2023/12/21/ijgc-2023-004995.full.pdf
- OA Status
- hybrid
- Cited By
- 42
- References
- 24
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4390078374
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4390078374Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1136/ijgc-2023-004995Digital Object Identifier
- Title
-
Updated progression-free survival and final overall survival with maintenance olaparib plus bevacizumab according to clinical risk in patients with newly diagnosed advanced ovarian cancer in the phase III PAOLA-1/ENGOT-ov25 trialWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-12-22Full publication date if available
- Authors
-
Domenica Lorusso, Marie‐Ange Mouret‐Reynier, Philipp Harter, Claire Cropet, Cristina Caballero, P Wolfrum-Ristau, Toyomi Satoh, Ignace Vergote, Gabriella Parma, Trine Jakobi Nøttrup, Coriolan Lebreton, Peter A. Fasching, Carmela Pisano, Luís Manso, Hugues Bourgeois, Ingo B. Runnebaum, Claudio Zamagni, Anne‐Claire Hardy‐Bessard, Andreas Schnelzer, Michel Fabbro, Barbara Schmalfeldt, Dominique Berton, Antje Belau, Jean‐Pierre Lotz, Martina Gropp‐Meier, Laurence Gladieff, Hans‐Joachim Lück, Sophie Abadie‐Lacourtoisie, Éric Pujade-Lauraine, Isabelle Ray‐CoquardList of authors in order
- Landing page
-
https://doi.org/10.1136/ijgc-2023-004995Publisher landing page
- PDF URL
-
https://ijgc.bmj.com/content/ijgc/early/2023/12/21/ijgc-2023-004995.full.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://ijgc.bmj.com/content/ijgc/early/2023/12/21/ijgc-2023-004995.full.pdfDirect OA link when available
- Concepts
-
Medicine, Olaparib, Bevacizumab, Ovarian cancer, Oncology, Internal medicine, Overall survival, Progression-free survival, Maintenance therapy, Cancer, Chemotherapy, Gene, Poly ADP ribose polymerase, Polymerase, Chemistry, BiochemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
42Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 31, 2024: 11Per-year citation counts (last 5 years)
- References (count)
-
24Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| title | Updated progression-free survival and final overall survival with maintenance olaparib plus bevacizumab according to clinical risk in patients with newly diagnosed advanced ovarian cancer in the phase III PAOLA-1/ENGOT-ov25 trial |
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