Updates on Diagnosis, Clinical Presentation, and Management of Ocular Cicatricial Pemphigoid (OCP): A Systematic Review Article Swipe

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Presentation (obstetrics) Cicatricial pemphigoid Medicine Dermatology Pemphigoid Surgery Immunology Bullous pemphigoid Antibody

Hyder Osman Mirghani , Aedah Alqrid , Hadeel Albalawi , Saud Qasem A Alshabab , Dana Aljezany , Hamdan S. Alghamdi , Khalid Aljohani , Mohammed Almousa , Ali Alshehri , Zeyad Alahmri , Sara Alsaidalani , Abdullah Alshahrani , Salman Ali A Alshamrani ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.54293/smhj.v4i2.106 · OA: W4395702385

This study systematically searched literature on the diagnosis, clinical presentation, and management of ocular chronic pain (OCP), including eight studies with 168 patients. The most reliable method of diagnosis was biopsy, with inflammatory markers detected in a small proportion of patients. Some patients had systemic or oral involvement and associated Sjogren's syndrome. Common immune-suppressives were MFF and steroids. Cyclophosphamide is a good choice in severe cases. Methotrexate and Rituximab were used as a maintenance therapy. OCP is characterized by ocular involvement that progresses to fibrosis and scarring. Diagnostic hurdles and inconclusive results make a comprehensive examination and clinical suspicion crucial.