Use of first bicarbonate after out-of-hospital cardiac arrest to predict mortality Article Swipe
Teresa López‐Sobrino
,
M. Ribas
,
FR Jimenez Trinidad
,
PL Cepas Guillen
,
Eduardo Flores‐Umanzor
,
Orenzio Soler
,
Ana Paula Dantas
,
Anthony Salazar
,
Leticia Castrillo
,
B J Ayala Borges
,
E Moreno Monterde
,
C Gillermo Galvez
,
C Martinez Gea
,
Juan Carlos Valerio-Rojas
,
Rut Andrea
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1093/ehjacc/zuac041.047
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1093/ehjacc/zuac041.047
Funding Acknowledgements Type of funding sources: None. Background Recovered out-of-hospital cardiac arrest (OHCA) is associated with high morbidity and mortality. Having prognostic tools within the first hours of admission to hospital is critical. The pH is a widespread arterial blood gas marker, but the influence of its respiratory/metabolic components has not yet been established. Purpose The objective of the study is to analyze the utility of first bicarbonate measure as a predictor of in-hospital mortality after OHCA. Methods This is a prospective observational study carried out on survivors to the initial phase of an OHCA, who were admitted to the Acute Cardiovascular Care Unit of our single terciary center. Clinical characteristics and initial blood gas data were analyzed. The primary objective was in-hospital mortality. Results A total of 50 patients were included (2019-2021), of which 40% died during the course of the hospitalization. First pH determination showed significant differences between survivors and dead. Of its two components, the bicarbonate was lower in the patients who died (13.93 ± 3.01 vs. 18.48 ± 4.15, p <0.001) while the CO2 partial pressure (PCO2) did not show differences (53.89 ± 14.43 vs. 50.31 ± 13.07, p = 0.377). A ROC analysis was performed, and the bicarbonate had the best AUC as a mortality predictor (0.819, CI 95% 0.695-0.944, p<0.0001), compared to lactate (0.793, CI 95% 0.663-0.923, p=0.001) and pH (0.781, CI 95% 0.650-0.913, p=0.001). The best cut-off value for bicarbonate was 16.5 mmol / L (Log-rank < 0.0001), with a sensitivity of 84% and a specificity of 79% to predict survival. Conclusions Bicarbonate was the best initial predictor of mortality after an OHCA, above pH, which, although being a good predictor, is potentially altered by PCO2 (which was not a good predictor).
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/ehjacc/zuac041.047
- https://academic.oup.com/ehjacc/article-pdf/11/Supplement_1/zuac041.047/43519803/zuac041.047.pdf
- OA Status
- bronze
- Cited By
- 1
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4229022484
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4229022484Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1093/ehjacc/zuac041.047Digital Object Identifier
- Title
-
Use of first bicarbonate after out-of-hospital cardiac arrest to predict mortalityWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-05-01Full publication date if available
- Authors
-
Teresa López‐Sobrino, M. Ribas, FR Jimenez Trinidad, PL Cepas Guillen, Eduardo Flores‐Umanzor, Orenzio Soler, Ana Paula Dantas, Anthony Salazar, Leticia Castrillo, B J Ayala Borges, E Moreno Monterde, C Gillermo Galvez, C Martinez Gea, Juan Carlos Valerio-Rojas, Rut AndreaList of authors in order
- Landing page
-
https://doi.org/10.1093/ehjacc/zuac041.047Publisher landing page
- PDF URL
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https://academic.oup.com/ehjacc/article-pdf/11/Supplement_1/zuac041.047/43519803/zuac041.047.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
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bronzeOpen access status per OpenAlex
- OA URL
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https://academic.oup.com/ehjacc/article-pdf/11/Supplement_1/zuac041.047/43519803/zuac041.047.pdfDirect OA link when available
- Concepts
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Medicine, Bicarbonate, Intensive care unit, pCO2, Internal medicine, Prospective cohort study, Observational study, Emergency medicine, Cardiology, Intensive care medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
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1Total citation count in OpenAlex
- Citations by year (recent)
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2025: 1Per-year citation counts (last 5 years)
- Related works (count)
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10Other works algorithmically related by OpenAlex
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