Vaccination hesitancy and conspiracy beliefs associated with COVID-19 vaccination behaviours in young adults in the UK: A cross-sectional cohort study Article Swipe
Leo Salter
,
Catherine Heidi Seage
,
Rhiannon Phillips
,
Stephanie Brown
,
Delyth James
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-6413155/v1
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-6413155/v1
Background Vaccination significantly reduces mortality from COVID-19; however, uptake has declined, with most vaccine hesitancy observed among young adults. Reasons behind low COVID-19 vaccine uptake in this population are poorly understood. The aim of this study was to investigate the role of conspiracy theory mentality and vaccination beliefs as potential predictors of COVID-19 vaccination adherence behaviours (i.e. vaccine hesitancy and uptake). Methods A cross-sectional design was adopted using an online survey, where validated questionnaires adapted for COVID-19 were distributed to one university cohort and on social media platforms targeting young adults in the UK (students aged 18–25-years-old). In this cohort study, quantitative measures included beliefs about vaccinations (Beliefs about Medicines Questionnaire [BMQ] – BMQ-Specific adapted for COVID-19 vaccination and BMQ-General adapted for vaccinations in general), conspiracy theory mentality (Vaccine Conspiracy Beliefs Scale - COVID-19) and vaccine hesitancy (Oxford Vaccine Hesitancy Scale). Vaccine uptake was measured by capturing the number of self-reported doses of COVID-19 vaccination received. Demographic characteristics were also collected and linear regression analysis conducted to identify determinants of vaccination behaviours. Results One hundred and sixty-three valid responses were analyzed. All adapted scales showed acceptable internal consistency (Cronbach’s alpha values > 0.64). COVID-19 vaccination beliefs (BMQ-Necessity-Concerns Differential), age and conspiracy mentality were significantly associated with vaccine hesitancy (F = 76.6; Variance = 71.2%, adjusted R2 = 0.703). Only COVID-19 vaccine beliefs (Necessity-Concerns Differential) was predictive of vaccine uptake (F = 14.866, Variance = 22.9%, adjusted R2 = 0.214). Increasing age was also associated with more negative vaccination beliefs (BMQ-Concerns - Beta = 0.707, t = 6.824, p < 0.001: BMQ-Necessity- Beta =-0.882, t=-9.558, p < 0.001) and vaccine hesitancy (Beta = 1.976, t = 2.481, p < 0.05), but not vaccine uptake. Conclusions These findings indicate that effective strategies to decrease vaccine hesitancy and promote vaccine uptake among young adults in the UK should aim to modify the underlying psychological factors that drive misconceptions about COVID-19 vaccination and conspiracy beliefs.
Related Topics
Concepts
Vaccination
Coronavirus disease 2019 (COVID-19)
Cross-sectional study
Cohort
Medicine
2019-20 coronavirus outbreak
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Cohort study
Young adult
Virology
Family medicine
Demography
Environmental health
Gerontology
Outbreak
Disease
Sociology
Internal medicine
Pathology
Infectious disease (medical specialty)
Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.21203/rs.3.rs-6413155/v1
- https://www.researchsquare.com/article/rs-6413155/latest.pdf
- OA Status
- gold
- References
- 61
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4411344140
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4411344140Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.21203/rs.3.rs-6413155/v1Digital Object Identifier
- Title
-
Vaccination hesitancy and conspiracy beliefs associated with COVID-19 vaccination behaviours in young adults in the UK: A cross-sectional cohort studyWork title
- Type
-
preprintOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-06-16Full publication date if available
- Authors
-
Leo Salter, Catherine Heidi Seage, Rhiannon Phillips, Stephanie Brown, Delyth JamesList of authors in order
- Landing page
-
https://doi.org/10.21203/rs.3.rs-6413155/v1Publisher landing page
- PDF URL
-
https://www.researchsquare.com/article/rs-6413155/latest.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
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https://www.researchsquare.com/article/rs-6413155/latest.pdfDirect OA link when available
- Concepts
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Vaccination, Coronavirus disease 2019 (COVID-19), Cross-sectional study, Cohort, Medicine, 2019-20 coronavirus outbreak, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Cohort study, Young adult, Virology, Family medicine, Demography, Environmental health, Gerontology, Outbreak, Disease, Sociology, Internal medicine, Pathology, Infectious disease (medical specialty)Top concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
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61Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| publication_date | 2025-06-16 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W4393094079, https://openalex.org/W3020062806, https://openalex.org/W3215756704, https://openalex.org/W4200039328, https://openalex.org/W3210511233, https://openalex.org/W4401003606, https://openalex.org/W2084518431, https://openalex.org/W4225253941, https://openalex.org/W3119977046, https://openalex.org/W3049397161, https://openalex.org/W4377091678, https://openalex.org/W4317359897, https://openalex.org/W2038795551, https://openalex.org/W4296251680, https://openalex.org/W3193541631, https://openalex.org/W4406189737, https://openalex.org/W3137473975, https://openalex.org/W3107807236, https://openalex.org/W3179667819, https://openalex.org/W3111141362, https://openalex.org/W2142313870, https://openalex.org/W3016902371, https://openalex.org/W3023613004, https://openalex.org/W3179475117, https://openalex.org/W4400850262, https://openalex.org/W3088599983, https://openalex.org/W3092934210, https://openalex.org/W3148139713, https://openalex.org/W2162633278, https://openalex.org/W6771072406, https://openalex.org/W3154657052, https://openalex.org/W4229029663, https://openalex.org/W2061935394, https://openalex.org/W4200103068, https://openalex.org/W4388141842, https://openalex.org/W3093974194, https://openalex.org/W3134167050, https://openalex.org/W4401114566, https://openalex.org/W4392716045, https://openalex.org/W3092858700, https://openalex.org/W4362471436, https://openalex.org/W3098344890, https://openalex.org/W3087714840, https://openalex.org/W3086309603, https://openalex.org/W3135098866, https://openalex.org/W4281943265, https://openalex.org/W4293723490, https://openalex.org/W4283258990, https://openalex.org/W3111674506, https://openalex.org/W4383723704, https://openalex.org/W3211031248, https://openalex.org/W3137613263, https://openalex.org/W4280603437, https://openalex.org/W4205857768, https://openalex.org/W4317651673, https://openalex.org/W3176121743, https://openalex.org/W3201810882, https://openalex.org/W4294920874, https://openalex.org/W4224317654, https://openalex.org/W649340631, https://openalex.org/W2991759146 |
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