Vaccinations Included in the National Immunization Calendar as a Tool to Tackle Antimicrobial Resistance: Current Evidence for Selected Pathogens in Italy Article Swipe
Giulia Marchetti
,
Paolo Castiglia
,
Andrea Lombardi
,
Federico Marchetti
,
Giovanni Gabutti
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/vaccines13111141
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/vaccines13111141
Background/Objectives: Antimicrobial (AMR) and antibiotic resistance (AR) remain major growing issues around the world. According to WHO, vaccinations play a strategic role in tackling AMR/AR; the new (upcoming) or existing vaccines (both viral and bacterial) directed toward resistant pathogens, may consistently reduce the overall burden of infectious diseases across the population. The objective of the present work is to review the available evidence on the impact that immunization schedules might exert in terms of antibiotic use reduction, focusing on vaccinations included in the Italian National Immunization Plan (NIP). Methods: A targeted literature search, limited to 2015–2025, was performed in the PubMed database to identify the available evidence on the impact that vaccinations exert on antibiotic use or reduction. Results: The search provided evidence on the potential impact that immunizations included in the NIP might exert in tackling AMR/AR. Influenza and pneumococcal vaccinations proved to be those with the broadest base of evidence in reducing antibiotic prescriptions. Preliminary local evidence also suggests an impact on reducing antibiotic use for RSV immunization among adults and older adults. Rotavirus vaccination proved to reduce antibiotic prescriptions, while varicella disease was associated with a relevant use of antibiotics. Conclusions: Vaccines are essential in the fight against AMR/AR. In this review the evidence on the impact that vaccinations included in the NIP may exert was compacted. The impact of vaccines on reducing AMR/AR should be recognized by Italian stakeholders and strategies and implementation plans should always include vaccines as interventions to reduce AMR/AR.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/vaccines13111141
- https://www.mdpi.com/2076-393X/13/11/1141/pdf?version=1762351824
- OA Status
- gold
- OpenAlex ID
- https://openalex.org/W4415930491
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4415930491Canonical identifier for this work in OpenAlex
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https://doi.org/10.3390/vaccines13111141Digital Object Identifier
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Vaccinations Included in the National Immunization Calendar as a Tool to Tackle Antimicrobial Resistance: Current Evidence for Selected Pathogens in ItalyWork title
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articleOpenAlex work type
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enPrimary language
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2025Year of publication
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2025-11-05Full publication date if available
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Giulia Marchetti, Paolo Castiglia, Andrea Lombardi, Federico Marchetti, Giovanni GabuttiList of authors in order
- Landing page
-
https://doi.org/10.3390/vaccines13111141Publisher landing page
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https://www.mdpi.com/2076-393X/13/11/1141/pdf?version=1762351824Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.mdpi.com/2076-393X/13/11/1141/pdf?version=1762351824Direct OA link when available
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