Variation in cartilage T2 and T2* mapping of the wrist: a comparison between 3- and 7-T MRI Article Swipe
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· 2023
· Open Access
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· DOI: https://doi.org/10.1186/s41747-023-00394-1
Background To analyze regional variations in T2 and T2* relaxation times in wrist joint cartilage and the triangular fibrocartilage complex (TFCC) at 3 and 7 T and to compare values between field strengths. Methods Twenty-five healthy controls and 25 patients with chronic wrist pain were examined at 3 and 7 T on the same day using T2- and T2*-weighted sequences. Six different regions of interest (ROIs) were evaluated for cartilage and 3 ROIs were evaluated at the TFCC based on manual segmentation. Paired t -tests were used to compare T2 and T2* values between field strengths and between different ROIs. Spearman’s rank correlation was calculated to assess correlations between T2 and T2* time values at 3 and 7 T. Results T2 and T2* time values of the cartilage differed significantly between 3 and 7 T for all ROIs ( p ≤ 0.045), with one exception: at the distal lunate, no significant differences in T2 values were observed between field strengths. T2* values differed significantly between 3 and 7 T for all ROIs of the TFCC ( p ≤ 0.001). Spearman’s rank correlation between 3 and 7 T ranged from 0.03 to 0.62 for T2 values and from 0.01 to 0.48 for T2* values. T2 and T2* values for cartilage varied across anatomic locations in healthy controls at both 3 and 7 T. Conclusion Quantitative results of T2 and T2* mapping at the wrist differ between field strengths, with poor correlation between 3 and 7 T. Local variations in cartilage T2 and T2* values are observed in healthy individuals. Relevance statement T2 and T2* mapping are feasible for compositional imaging of the TFCC and the cartilage at the wrist at both 3 and 7 T, but the clinical interpretation remains challenging due to differences between field strengths and variations between anatomic locations. Key points •Field strength and anatomic locations influence T2 and T2* values at the wrist. •T2 and T2* values have a poor correlation between 3 and 7 T. •Local reference values are needed for each anatomic location for reliable interpretation. Graphical Abstract
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1186/s41747-023-00394-1
- https://eurradiolexp.springeropen.com/counter/pdf/10.1186/s41747-023-00394-1
- OA Status
- gold
- Cited By
- 2
- References
- 49
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4389703496
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4389703496Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1186/s41747-023-00394-1Digital Object Identifier
- Title
-
Variation in cartilage T2 and T2* mapping of the wrist: a comparison between 3- and 7-T MRIWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-12-14Full publication date if available
- Authors
-
R. Heiß, Marc‐André Weber, Eva L. Balbach, Maximilian Hinsen, Frederik Geissler, Armin M. Nagel, Mark E. Ladd, Andreas Arkudas, Raymund E. Horch, Christine M. Gall, Michael Uder, Frank W. RoemerList of authors in order
- Landing page
-
https://doi.org/10.1186/s41747-023-00394-1Publisher landing page
- PDF URL
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https://eurradiolexp.springeropen.com/counter/pdf/10.1186/s41747-023-00394-1Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
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-
goldOpen access status per OpenAlex
- OA URL
-
https://eurradiolexp.springeropen.com/counter/pdf/10.1186/s41747-023-00394-1Direct OA link when available
- Concepts
-
Wrist, Medicine, Cartilage, Rank correlation, Spearman's rank correlation coefficient, Nuclear medicine, Osteoarthritis, Correlation, Lunate, Anatomy, Pathology, Mathematics, Statistics, Geometry, Alternative medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
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2Total citation count in OpenAlex
- Citations by year (recent)
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2025: 1, 2024: 1Per-year citation counts (last 5 years)
- References (count)
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49Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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