Variation of subclinical psychosis as a function of population density across different European settings: Findings from the multi‐national EU ‐ GEI study
Article Swipe
Giuseppe D’Andrea
,
Diego Quattrone
,
Giada Tripoli
,
Edoardo Spinazzola
,
Charlotte Gayer‐Anderson
,
Hannah E. Jongsma
,
Lucia Sideli
,
Simona A. Stilo
,
Caterina La Cascia
,
Laura Ferraro
,
Daniele La Barbera
,
Andrea Tortelli
,
Eva Velthorst
,
Lieuwe de Haan
,
Pierre‐Michel Llorca
,
José Luis Santos
,
Manuel Arrojo
,
Julio Bobes
,
Julio Sanjuán
,
Miquel Bernardo
,
Celso Arango
,
James B. Kirkbride
,
Peter M. Jones
,
Bart P. F. Rutten
,
Franck Schürhoff
,
Andreı̈ Szöke
,
Jim van Os
,
Evangelos Vassos
,
Jean‐Paul Selten
,
Craig Morgan
,
Marta Di Forti
,
Ilaria Tarricone
,
Robin Murray
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1111/acps.13767
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1111/acps.13767
Background Urbanicity is a well‐established risk factor for psychosis. Our recent multi‐national study found an association between urbanicity and clinical psychosis in Northern Europe but not in Southern Europe. In this study, we hypothesized that the effect of current urbanicity on variation of schizotypy would be greater in North‐western Europe countries than in Southern Europe ones. Methods We recruited 1080 individuals representative of the populations aged 18–64 of 14 different sites within 5 countries, classified as either North‐western Europe (England, France, and The Netherlands) with Southern Europe (Spain and Italy). Our main outcome was schizotypy, assessed through the Structured Interview for Schizotypy‐Revised. Our main exposure was current urbanicity, operationalized as local population density. A priori confounders were age, sex, ethnic minority status, childhood maltreatment, and social capital. Schizotypy variation was assessed using multi‐level regression analysis. To test the differential effect of urbanicity between North‐western and Southern European, we added an interaction term between population density and region of recruitment. Results Population density was associated with schizotypy ( β = 0.248,95%CI = 0.122–0.375; p < 0.001). The addition of the interaction term improved the model fit (likelihood test ratio: χ 2 = 6.85; p = 0.009). The effect of urbanicity on schizotypy was substantially stronger in North‐western Europe ( β = 0.620,95%CI = 0.362–0.877; p < 0.001) compared with Southern Europe ( β = 0.190,95%CI = 0.083–0.297; p = 0.001). Conclusions The association between urbanicity and both subclinical schizotypy and clinical psychosis, rather than being universal, is context‐specific. Considering that urbanization is a rapid and global process, further research is needed to disentangle the specific factors underlying this relationship.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/acps.13767
- OA Status
- green
- References
- 73
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4403987748
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4403987748Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/acps.13767Digital Object Identifier
- Title
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Variation of subclinical psychosis as a function of population density across different European settings: Findings from the multi‐national
EU ‐GEI studyWork title - Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-11-01Full publication date if available
- Authors
-
Giuseppe D’Andrea, Diego Quattrone, Giada Tripoli, Edoardo Spinazzola, Charlotte Gayer‐Anderson, Hannah E. Jongsma, Lucia Sideli, Simona A. Stilo, Caterina La Cascia, Laura Ferraro, Daniele La Barbera, Andrea Tortelli, Eva Velthorst, Lieuwe de Haan, Pierre‐Michel Llorca, José Luis Santos, Manuel Arrojo, Julio Bobes, Julio Sanjuán, Miquel Bernardo, Celso Arango, James B. Kirkbride, Peter M. Jones, Bart P. F. Rutten, Franck Schürhoff, Andreı̈ Szöke, Jim van Os, Evangelos Vassos, Jean‐Paul Selten, Craig Morgan, Marta Di Forti, Ilaria Tarricone, Robin MurrayList of authors in order
- Landing page
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https://doi.org/10.1111/acps.13767Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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greenOpen access status per OpenAlex
- OA URL
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https://iris.unipa.it/bitstream/10447/672549/2/Acta%20Psychiatr%20Scand%20-%202024%20-%20D_Andrea%20-%20Variation%20of%20subclinical%20psychosis%20as%20a%20function%20of%20population%20density%20across.pdfDirect OA link when available
- Concepts
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Schizotypy, Demography, Population, Subclinical infection, Psychology, Psychosis, Environmental health, Geography, Medicine, Psychiatry, Sociology, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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