Vasculitic wheel – an algorithmic approach to cutaneous vasculitides Article Swipe
Gudrun Ratzinger
,
Bettina Zelger
,
J. Andrew Carlson
,
Walter H. C. Burgdorf
,
Bernhard Zelger
·
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.1111/ddg.12859
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.1111/ddg.12859
Summary Background Previous classifications of vasculitides suffer from several defects. First, classifications may follow different principles including clinicopathologic findings, etiology, pathogenesis, prognosis, or therapeutic options. Second, authors fail to distinguish between vasculitis and coagulopathy. Third, vasculitides are systemic diseases. Organ‐specific variations make morphologic findings difficult to compare. Fourth, subtle changes are recognized in the skin, but may be asymptomatic in other organs. Our aim was to use the skin and subcutis as a model and the clinicopathologic correlation as the basic process for classification. Methods and Results We use an algorithmic approach with pattern analysis, which allows for consistent reporting of microscopic findings. We first differentiate between small and medium vessel vasculitis. In the second step, we differentiate the subtypes of small (capillaries versus postcapillary venules) and medium‐sized (arterioles/arteries versus veins) vessels. In the final step, we differentiate, according to the predominant cell type, into leukocytoclastic and/or granulomatous vasculitis. Conclusions Starting from leukocytoclastic vasculitis as a central reaction pattern of cutaneous small/medium vessel vasculitides, its relations or variations may be arranged around it like spokes of a wheel around the hub. This may help establish some basic order in this rather complex realm of cutaneous vasculitides, leading to a better understanding in a complicated field.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1111/ddg.12859
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ddg.12859
- OA Status
- bronze
- Cited By
- 35
- References
- 99
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W1879194960
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W1879194960Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/ddg.12859Digital Object Identifier
- Title
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Vasculitic wheel – an algorithmic approach to cutaneous vasculitidesWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2015Year of publication
- Publication date
-
2015-10-29Full publication date if available
- Authors
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Gudrun Ratzinger, Bettina Zelger, J. Andrew Carlson, Walter H. C. Burgdorf, Bernhard ZelgerList of authors in order
- Landing page
-
https://doi.org/10.1111/ddg.12859Publisher landing page
- PDF URL
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ddg.12859Direct link to full text PDF
- Open access
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YesWhether a free full text is available
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bronzeOpen access status per OpenAlex
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ddg.12859Direct OA link when available
- Concepts
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Medicine, Dermatology, Cutaneous Vasculitis, Vasculitis, Pathology, DiseaseTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
35Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2023: 3, 2022: 3, 2021: 3, 2020: 7Per-year citation counts (last 5 years)
- References (count)
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99Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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