Vitamin D Levels among Chronic Kidney Disease Patients at a Tertiary Care Hospital: A Cross-sectional Study Article Swipe
Matta Sreevani
,
B. Srinivasa Rao
,
S Srivanvani
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.7860/njlm/2024/59460.2821
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.7860/njlm/2024/59460.2821
Introduction: In patients with Chronic Kidney Disease (CKD), a high prevalence of metabolite abnormalities has been observed. Numerous studies have demonstrated that individuals with reduced Glomerular Filtration Rate (GFR) are more susceptible to severe vitamin D deficiency compared to those with normal kidney function. Aim: To investigate the association between vitamin D levels and the severity of CKD among patients at Siddhartha Medical College, GGH in Vijayawada, Andhra Pradesh, India. Materials and Methods: The present hospital-based cross- sectional study was conducted at Siddhartha Medical College, GGH, Vijayawada, Andhra Pradesh, India from December 2021 to February 2022. A total of 100 CKD patients with a GFR of less than 60 mL/min/1.72 m2 were included in the study. Vitamin D levels were assessed using Chemiluminescence immunoassay (Access 2, Beckman Coulter), and vitamin D deficiency was defined as 25-OH vitamin D levels of less than 10 ng/mL, while insufficiency was defined as levels between 10 to 30 ng/mL. Statistical analysis was performed using Analysis of Variance (ANOVA) test and Pearson’s correlation test. Results: The mean age of the study population was 53.25±7.6 years, with the majority (32%) belonging to the 51-60 years age group. In terms of gender distribution, approximately three-fourths (72%) of the subjects were male. Hypertension was present in 44% of CKD patients, diabetes in 38%, and cardiovascular disease in 38%. Total 53% of CKD patients were classified as stage 4 on the Kidney Disease: Improving Global Outcome (KDIGO) CKD staging. Vitamin D deficiency was observed in 26% of patients, while 39% had insufficiency. A statistically significant association was found between the severity of CKD staging and mean vitamin D levels, with lower mean levels observed in stages 4 and 5. Conclusion: Vitamin D deficiency was present in one-fourth of the CKD patients, and it was more pronounced in advanced stages of CKD.
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- Type
- article
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- en
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- http://doi.org/10.7860/njlm/2024/59460.2821
- OA Status
- gold
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https://openalex.org/W4395476868Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.7860/njlm/2024/59460.2821Digital Object Identifier
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Vitamin D Levels among Chronic Kidney Disease Patients at a Tertiary Care Hospital: A Cross-sectional StudyWork title
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articleOpenAlex work type
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enPrimary language
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2024Year of publication
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2024-01-01Full publication date if available
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Matta Sreevani, B. Srinivasa Rao, S SrivanvaniList of authors in order
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https://doi.org/10.7860/njlm/2024/59460.2821Publisher landing page
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goldOpen access status per OpenAlex
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https://doi.org/10.7860/njlm/2024/59460.2821Direct OA link when available
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Cross-sectional study, Medicine, Kidney disease, Tertiary care, Internal medicine, Pediatrics, PathologyTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2024: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.individuals | 22 |
| abstract_inverted_index.investigate | 46 |
| abstract_inverted_index.mL/min/1.72 | 109 |
| abstract_inverted_index.significant | 255 |
| abstract_inverted_index.susceptible | 31 |
| abstract_inverted_index.Hypertension | 204 |
| abstract_inverted_index.demonstrated | 20 |
| abstract_inverted_index.Introduction: | 0 |
| abstract_inverted_index.abnormalities | 13 |
| abstract_inverted_index.approximately | 196 |
| abstract_inverted_index.distribution, | 195 |
| abstract_inverted_index.insufficiency | 145 |
| abstract_inverted_index.statistically | 254 |
| abstract_inverted_index.three-fourths | 197 |
| abstract_inverted_index.cardiovascular | 216 |
| abstract_inverted_index.hospital-based | 75 |
| abstract_inverted_index.insufficiency. | 252 |
| abstract_inverted_index.Chemiluminescence | 122 |
| cited_by_percentile_year.max | 94 |
| cited_by_percentile_year.min | 90 |
| countries_distinct_count | 0 |
| institutions_distinct_count | 3 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7200000286102295 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.6375612 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |