Weight gain in infancy and metabolic dysfunction-associated steatotic liver disease (MASLD) in a prospective birth cohort of Latino children Article Swipe
Sarah Maxwell
,
Jennifer C. Price
,
Emily R. Perito
,
Philip Rosenthal
,
Janet M. Wojcicki
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1186/s40748-025-00225-8
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1186/s40748-025-00225-8
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease among U.S. children. Early weight trajectories correlate with obesity, cardiometabolic syndrome, and MASLD in children born small for gestational age. Methods We evaluated whether increases in weight-for-age (WAZ) score from 0 to 6 months of life, are associated with MASLD in middle childhood, in two prospective birth cohorts of healthy Latino children ( n = 136). Results After adjusting for confounders, increases in WAZ score from 0 to 6 months of age were associated with a higher risk for MASLD in middle childhood (OR 1.54 95% CI, 1.01–2.36; p = 0.046). Conclusions In a prospective study of Latino children, increases in WAZ score from 0 to 6 months were associated with increased risk of MASLD in mid-childhood. This could inform early screening and counseling for MASLD.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1186/s40748-025-00225-8
- https://mhnpjournal.biomedcentral.com/counter/pdf/10.1186/s40748-025-00225-8
- OA Status
- gold
- References
- 37
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4413137514
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4413137514Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1186/s40748-025-00225-8Digital Object Identifier
- Title
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Weight gain in infancy and metabolic dysfunction-associated steatotic liver disease (MASLD) in a prospective birth cohort of Latino childrenWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-08-14Full publication date if available
- Authors
-
Sarah Maxwell, Jennifer C. Price, Emily R. Perito, Philip Rosenthal, Janet M. WojcickiList of authors in order
- Landing page
-
https://doi.org/10.1186/s40748-025-00225-8Publisher landing page
- PDF URL
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https://mhnpjournal.biomedcentral.com/counter/pdf/10.1186/s40748-025-00225-8Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
- OA URL
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https://mhnpjournal.biomedcentral.com/counter/pdf/10.1186/s40748-025-00225-8Direct OA link when available
- Concepts
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Medicine, Prospective cohort study, Pediatrics, Cohort, Weight gain, Cohort study, Internal medicine, Body weightTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
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37Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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