What is the added value of patch testing with 30 fragrance allergens in addition to the European Baseline series? Article Swipe
Rosalie C. Krijl
,
Norbertus A. Ipenburg
,
Sylvie M. Franken
,
Thomas Rustemeyer
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1111/cod.14065
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1111/cod.14065
Background Patch testing with the fragrance allergy markers in the European baseline series (EBS) does not identify all patients with fragrance allergy. Hydroperoxides of linalool and limonene have been shown to be useful allergens in detecting fragrance sensitization. Objectives To evaluate the added value of testing with 30 fragrance allergens in addition to the EBS. Methods All patients with suspected fragrance allergy who underwent patch testing at the Amsterdam University Medical Centers between November 2019 and January 2021 to the EBS and fragrance series were included. Results Of 323 patients tested, 162 (50.2%) were found to be fragrance sensitized. The most sensitizing single allergens were the hydroperoxides of linalool (1.0 and 0.5% pet.) and limonene (0.3 and 0.2% pet.). Testing with the hydroperoxides of linalool and limonene identified 62 fragrance‐sensitized patients (38.3%) who could not be detected by the common fragrance markers. Of all fragrance‐sensitized patients, 21 (13.0%) would have been missed when not testing with the fragrance series. Conclusions Patch testing with the fragrance series in addition to the EBS is valuable. To reduce the risk of false‐negative reactions, it is advisable to test the hydroperoxides of linalool and limonene.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/cod.14065
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cod.14065
- OA Status
- hybrid
- Cited By
- 7
- References
- 37
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4210497874
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4210497874Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/cod.14065Digital Object Identifier
- Title
-
What is the added value of patch testing with 30 fragrance allergens in addition to the European Baseline series?Work title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2022Year of publication
- Publication date
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2022-02-05Full publication date if available
- Authors
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Rosalie C. Krijl, Norbertus A. Ipenburg, Sylvie M. Franken, Thomas RustemeyerList of authors in order
- Landing page
-
https://doi.org/10.1111/cod.14065Publisher landing page
- PDF URL
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cod.14065Direct link to full text PDF
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cod.14065Direct OA link when available
- Concepts
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Linalool, Patch testing, Limonene, Contact allergy, Ionone, Patch test, Allergy, Dermatology, Allergic contact dermatitis, Sensitization, Medicine, Chemistry, Contact dermatitis, Organic chemistry, Food science, Immunology, Essential oilTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
7Total citation count in OpenAlex
- Citations by year (recent)
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2024: 3, 2023: 2, 2022: 2Per-year citation counts (last 5 years)
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37Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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