When a Slice Is Not Enough! Comparison of Whole-Brain versus Standard Limited-Slice Perfusion Computed Tomography in Patients with Severe Traumatic Brain Injury Article Swipe
YOU?
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· 2019
· Open Access
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· DOI: https://doi.org/10.3390/jcm8050701
Introduction: Cerebral perfusion computed tomography (PCT) provides crucial information in acute stroke and has an increasing role in traumatic brain injury (TBI) management. Most studies on TBI patients utilize 64-slice scanners, which are limited to four brain slices (limited-brain PCT, LBPCT). Newer 320-slice scanners depict the whole brain perfusion status (WBPCT). We aimed to identify the additional information gained with WBPCT when compared to LBPCT. Patients and methods: Forty-nine patients with severe TBI were investigated within 48 h from admission with WBPCT. Findings from LBPCT were compared with findings from WBPCT. Results: A perfusion abnormality was identified in 39 (80%) and 37 (76%) patients by WBPCT and LBPCT, respectively (p = 0.8). There were 90 and 68 perfusion abnormalities identified by WBPCT and LBPCT, respectively (p < 0.001). In the 39 patients with a perfusion abnormality detected by WBPCT, 15 (38%) had further perfusion abnormalities outside the LBPCT area of coverage. Thirty-six (92%) patients had a larger perfusion abnormality upon WBPCT compared with LBPCT. Additional information gained showed some statistically significant correlation with clinical outcome. Conclusions: In severe TBI patients, WBPCT provides extra information compared to LBPC. The limitations of LBPCT should be considered when evaluating studies reporting on PCT findings and their association with outcomes.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/jcm8050701
- https://www.mdpi.com/2077-0383/8/5/701/pdf?version=1558088160
- OA Status
- gold
- References
- 15
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2945575528
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2945575528Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/jcm8050701Digital Object Identifier
- Title
-
When a Slice Is Not Enough! Comparison of Whole-Brain versus Standard Limited-Slice Perfusion Computed Tomography in Patients with Severe Traumatic Brain InjuryWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-05-17Full publication date if available
- Authors
-
Shannon Cooper, Cino Bendinelli, Andrew Bivard, Mark Parsons, Zsolt J. BaloghList of authors in order
- Landing page
-
https://doi.org/10.3390/jcm8050701Publisher landing page
- PDF URL
-
https://www.mdpi.com/2077-0383/8/5/701/pdf?version=1558088160Direct link to full text PDF
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-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.mdpi.com/2077-0383/8/5/701/pdf?version=1558088160Direct OA link when available
- Concepts
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Medicine, Perfusion, Traumatic brain injury, Perfusion scanning, Abnormality, Cerebral perfusion pressure, Radiology, Stroke (engine), Psychiatry, Mechanical engineering, EngineeringTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
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15Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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