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View article: Marine-derived Aspergillus sp.-mediated biosynthesis of silver nanoparticles with antioxidant activity and immunomodulatory apoptosis induction in melanoma cells
Marine-derived Aspergillus sp.-mediated biosynthesis of silver nanoparticles with antioxidant activity and immunomodulatory apoptosis induction in melanoma cells Open
In this work, we use a fungal isolate, Aspergillus sp. SO23, derived from a marine sponge collected from the coast of Hurghada, Egypt, to isolate, identify, and biosynthesis silver nanoparticles (Ag NPs). Following molecular and visual ide…
View article: 414 Effect of Curcuma longa on Blood Glucose, Lipid Metabolism, and Insulin Pathways in Diabetic Rodents
414 Effect of Curcuma longa on Blood Glucose, Lipid Metabolism, and Insulin Pathways in Diabetic Rodents Open
Introduction/Objective Diabetes mellitus is a chronic metabolic disorder marked by persistent hyperglycemia and impaired insulin signaling, often leading to serious long-term complications. Interest in plant-based therapies with antidiabet…
View article: 533 Comparative Analysis of Blood Product Utilization in Trauma Departments
533 Comparative Analysis of Blood Product Utilization in Trauma Departments Open
Introduction/Objective Understanding the utilization patterns of blood products across different trauma departments can inform targeted interventions. This study compares the ordering patterns of liquid plasma and thawed plasma in various …
View article: 50 Specialist in Blood Banking Certification: A Key to Excellence in Transfusion Services
50 Specialist in Blood Banking Certification: A Key to Excellence in Transfusion Services Open
Introduction/Objective The Specialist in Blood Banking (SBB) certification offered by the American Society of Clinical Pathology (ASCP) is a prestigious credential that signifies advanced expertise in transfusion medicine. With only about …
View article: Serologic investigation and management of an antibody screen negative para‐Bombay phenotype during pregnancy
Serologic investigation and management of an antibody screen negative para‐Bombay phenotype during pregnancy Open
Background Individuals with Bombay and para‐Bombay red blood cell (RBC) phenotypes produce anti‐H antibodies associated with acute haemolytic transfusion reactions. The rarity of compatible donor units creates unique logistical challenges,…
View article: Functional and radiological outcomes following sacroiliac screw fixation of posterior pelvic ring injuries: A retrospective study
Functional and radiological outcomes following sacroiliac screw fixation of posterior pelvic ring injuries: A retrospective study Open
Most patients with pelvic ring injuries experienced high-energy trauma, often resulting in multiple injuries and operative interventions. Nevertheless, mortality rates were low, and most patients experienced either mild or no functional di…
View article: The impact of frailty on functional recovery after cardiac surgery—a case control study
The impact of frailty on functional recovery after cardiac surgery—a case control study Open
Short- and medium-term measures of good functional recovery were lower in 'frail' patients, and longer-term survival was also significantly reduced. An accumulation of deficits assessment of frailty, incorporating multiple domains, builds …
View article: Decoding LncRNA in COPD: Unveiling Prognostic and Diagnostic Power and Their Driving Role in Lung Cancer Progression
Decoding LncRNA in COPD: Unveiling Prognostic and Diagnostic Power and Their Driving Role in Lung Cancer Progression Open
Chronic obstructive pulmonary disease (COPD) and lung cancer represent formidable challenges in global health, characterized by intricate pathophysiological mechanisms and multifaceted disease progression. This comprehensive review integra…
View article: Biogenic Green Synthesis of Zinc Oxide Nanoparticles from Defatted Coconut Presscake for Wastewater Treatment
Biogenic Green Synthesis of Zinc Oxide Nanoparticles from Defatted Coconut Presscake for Wastewater Treatment Open
Defatted coconut meat presscake is a by-product of coconut milk production, often discarded or used as low-value products, but has the potential to treat wastewater. This study aimed to characterize zinc oxide nanoparticles (ZnO NPs) synth…
View article: Adiponectin/resistin evaluation is a gold biomarker for monitoring CVD in patients with metabolic syndrome
Adiponectin/resistin evaluation is a gold biomarker for monitoring CVD in patients with metabolic syndrome Open
Introduction/Objective Introduction: Various studies have tried correlating specific inflammatory markers with metabolic syndrome. Serum adiponectin levels can serve as a biomarker that predicts metabolic syndrome development. Resistin is …
View article: Green Synthesis of Bioconjugated Magnetic Nanoparticles (MNPs) By Punica granatum And Its Applications As Anti-microbial Agent
Green Synthesis of Bioconjugated Magnetic Nanoparticles (MNPs) By Punica granatum And Its Applications As Anti-microbial Agent Open
Introduction In recent years, the development of efficient green chemistry methods for synthesizing metal nanoparticles has become a major focus of many researchers. Nanoparticles produced by plants are more stable, and the rate of synthes…
View article: The correlation between Plasma Fibrinogen Levels and Glycemic Status in type 2 Diabetes Mellitus
The correlation between Plasma Fibrinogen Levels and Glycemic Status in type 2 Diabetes Mellitus Open
Introduction/Objective Background: Fibrinogen is considered a well-known contributor to the progression of atherosclerotic lesions and a predictor of cardiovascular events. Patients with diabetes mellitus (DM) have higher levels of fibrino…
View article: Racial Disparity in Antibody Against A rare High Prevalence Antigen; (Anti-Inb)
Racial Disparity in Antibody Against A rare High Prevalence Antigen; (Anti-Inb) Open
Introduction/Objective Introduction: Ina antigen is very rare except in Iranian and Arab populations (10.6% and 11.8%, respectively). In 1973, Badkere et al. identified this antigen in about 3% of Indians from Bombay. Inb is a very high-pr…
View article: Prevalence and Distribution of ABO and Rh (D) Factor among Blood Donors in the United Arab of Emirates
Prevalence and Distribution of ABO and Rh (D) Factor among Blood Donors in the United Arab of Emirates Open
Introduction/Objective Karl Landsteiner discovered the ABO blood group system in 1900, which was the first human blood group system. The Rh blood group system was found forty years later. The antigens on the surface of red blood cells are …
View article: Benign High Prevalence Antibody Yta
Benign High Prevalence Antibody Yta Open
Introduction/Objective The Yt system, also known as the Cartwright system, discovered in 1964, consists of five antigens encoded by the ACHE gene on chromosome 7. Yta and Ytb are antithetical antigens on the GPI – linked red cell glycoprot…
View article: Invadopodia formation assay: a promising experiment for targeting breast cancer invasion and metastasis
Invadopodia formation assay: a promising experiment for targeting breast cancer invasion and metastasis Open
Introduction/Objective Invadopodia has been found to invade the extracellular matrix (ECM) in multiple cancers, including breast, lung, brain, and prostate, which is highly associated with cancer metastasis. Invadopodia have been shown to …
View article: The Diagnostic Performance of Serum Hyaluronic Acid and Collagen III in Differentiating Liver Fibrosis in HCV-Induced Patients
The Diagnostic Performance of Serum Hyaluronic Acid and Collagen III in Differentiating Liver Fibrosis in HCV-Induced Patients Open
Introduction/Objective Chronic liver diseases may lead to inflammation and progressive scarring, causing irreversible hepatic damage (cirrhosis). To avoid the complications of liver puncture biopsy, Collagen III and Hyaluronic acid are stu…
View article: Comparative study on the effect of bacteriophage on MDR E.coli from Urinary tract infections
Comparative study on the effect of bacteriophage on MDR E.coli from Urinary tract infections Open
Introduction/Objective Background: Urinary tract infections (UTIs) associated with urethral catheters are the most common infections during hospitalization. Hospitalization's most common infections are urethral catheter-related UTIs. Bacte…
View article: Blood Type Verification Rejection Rate Reduction
Blood Type Verification Rejection Rate Reduction Open
Introduction/Objective Specimen collection is an initial pre-analytical process that ensures accurate, reliable, and timely patient results. In accordance with AABB and CAP Standards, Transfusion Service rejects specimens if they do not me…
View article: Racial Disparity and Blood Group Antigens; COVID-19 High Mortality Rate in Black and Duffy Antigen
Racial Disparity and Blood Group Antigens; COVID-19 High Mortality Rate in Black and Duffy Antigen Open
Introduction/Objective As of March 5th, 2022, the novel coronavirus disease 2019 (COVID-19) has been confirmed in 464,809,377 people worldwide, with an approximately 1.31% mortality rate. COVID-19 infection is associated with an aggressive…
View article: Blood Products Wastage in Benghazi Hospitals, Libya: The Rate and Causes
Blood Products Wastage in Benghazi Hospitals, Libya: The Rate and Causes Open
Introduction/Objective Introduction: Despite the rising demand for blood and blood products, supplies are limited. Limiting blood wastage may compensate for fewer donors. This study examines blood waste in Benghazi. A close look at blood a…
View article: A rare cause of Acquired Hemolytic Anemia in a child; Donath-Landsteiner antibody
A rare cause of Acquired Hemolytic Anemia in a child; Donath-Landsteiner antibody Open
Introduction/Objective INTRODUCTION: The Donath-Landsteiner (DL) antibody is known to cause paroxysmal cold hemoglobinuria (PCH), a rare form of intravascular hemolytic anemia which is precipitated by an IgG biphasic hemolysin with specifi…
View article: Physico-Chemical Alternatives for Synthesis of Metal Nanoparticles Using Fusarium Chlamydosporum
Physico-Chemical Alternatives for Synthesis of Metal Nanoparticles Using Fusarium Chlamydosporum Open
Introduction/Objective Background: Synthesizing metal nanoparticles (NPs) by chemical or physical methods is difficult due to energy and time consumption, equipment costs, and chemical toxicity. Chemosynthesis-derived NPs are unstable, lim…
View article: Evaluation of lipoprotein(a) and adiponectin levels in patients with metabolic syndrome for the prediction of CVD risk
Evaluation of lipoprotein(a) and adiponectin levels in patients with metabolic syndrome for the prediction of CVD risk Open
Introduction/Objective Introduction: Metabolic syndrome (MetS) usually intensely forecasts cardiovascular diseases, along with elevating the risk of diabetes mellitus as well as chronic kidney disease. The International Federation for Diab…
View article: Viability of MDR bacteria against antibacterial biosynthesized ZnO and Au Nanoparticles
Viability of MDR bacteria against antibacterial biosynthesized ZnO and Au Nanoparticles Open
Introduction/Objective: Background Resistant strain diseases are increasing worldwide. Antimicrobials are concerned about pathogen-acquired resistance. Nanotechnology advances enable the creation of novel formulations based on various nano…
View article: The Correlation Between Serum Collagen III Levels and APRI in Liver Fibrotic HCV Patients
The Correlation Between Serum Collagen III Levels and APRI in Liver Fibrotic HCV Patients Open
Introduction/Objective Noninvasive Markers (NIM) of Liver Fibrosis help evaluate the stage of fibrosis in patients with no clear indication for a liver biopsy, such as patients with chronic hepatitis C who need monitoring of the stage of f…
View article: First Massive Transfusion Protocol (MTP) Implementation Proposal in Egypt
First Massive Transfusion Protocol (MTP) Implementation Proposal in Egypt Open
Introduction/Objective Massive transfusion is often defined as transfusion of adults with 10 or more of packed red blood cells units in 24 hours period or transfusion of 4 or more units of packed red blood cells (PRBCs) in one hour when on…
View article: Racial Disparity in Antibody Against High Prevalence Antigen; Anti-U
Racial Disparity in Antibody Against High Prevalence Antigen; Anti-U Open
Introduction/Objective Anti-U is an IgG antibody directed against the U antigen, which usually forms after exposure to U antigen via blood transfusion and/or pregnancy. U antigen is located on glycophorin B (GYPB) as part of the MNS blood …
View article: Biofilm Formation on Intrauterine Devices in Diabetic and Nondiabetic Patients with Vulvovaginal Candidiasis
Biofilm Formation on Intrauterine Devices in Diabetic and Nondiabetic Patients with Vulvovaginal Candidiasis Open
Introduction/Objective Women with diabetes mellitus (DM) are more susceptible to vulvovaginal candidiasis (VVC) than non-diabetics. This could be due to higher glucose levels predisposing VVC by damaging basic host defense mechanisms and s…
View article: In Vitro Activity of Clinically Used Farnesol and Other Antifungals Against Pre-formed<i>Candida albicans</i> Biofilms
In Vitro Activity of Clinically Used Farnesol and Other Antifungals Against Pre-formed<i>Candida albicans</i> Biofilms Open
Introduction/Objective Introduction: The emergence of antifungal resistance patients after long-term antifungal treatment shows an urgent need to develop new antifungal therapies. The ability of Candida albicans cells to form biofilm is re…