Johnson Adekunle Adeniji
YOU?
Author Swipe
View article: Molecular characterization and genetic diversity of norovirus strains recovered from stool of Nigerian children
Molecular characterization and genetic diversity of norovirus strains recovered from stool of Nigerian children Open
Introduction: Noroviruses (NoVs) are the leading causes of viral acute gastroenteritis (AGE). However, there is limited information on the molecular characterization and genetic diversity of NoVs in Nigeria. Methods: Archived stool samples…
View article: Ten Previously Unassigned Human Cosavirus Genotypes Detected in Feces of Children with Non-Polio Acute Flaccid Paralysis in Nigeria in 2020
Ten Previously Unassigned Human Cosavirus Genotypes Detected in Feces of Children with Non-Polio Acute Flaccid Paralysis in Nigeria in 2020 Open
Since its discovery via metagenomics in 2008, human cosavirus (HCoSV) has been detected in the cerebrospinal fluid (CSF) and feces of humans with meningitis, acute flaccid paralysis (AFP), and acute gastroenteritis. To date, 34 HCoSV genot…
View article: Antioxidant, bioactivity and cancer selective cytotoxicity potency of <i>Eulophia gracilis</i> successive extracts on selected cancer cells: An <i>in vitro</i> model
Antioxidant, bioactivity and cancer selective cytotoxicity potency of <i>Eulophia gracilis</i> successive extracts on selected cancer cells: An <i>in vitro</i> model Open
The metabolisms of many efficient chemotherapeutics are usually accompanied with health challenged toxic side effects and hence the need for more anticancer agents with little or no toxic consequences. The screening of medicinal plants wit…
View article: Design and Simulation of a rectangular Microstrip Patch Antenna using FR4 Substrate for Satellite Communication and IoT Device Applications
Design and Simulation of a rectangular Microstrip Patch Antenna using FR4 Substrate for Satellite Communication and IoT Device Applications Open
View article: An in vitro Evaluation of Periodontal Ligament Cell Viability in Honey as a Transport Medium for an Avulsed Tooth
An in vitro Evaluation of Periodontal Ligament Cell Viability in Honey as a Transport Medium for an Avulsed Tooth Open
Background Dental avulsion is the most severe form of injury to a tooth, and its prognosis is majorly affected by the type of the storage medium prior to re-implantation. Honey is a readily available household substance with anti-inflammat…
View article: Antimammary Tumour Effects of Calliandra portoricensis Fraction Via Pro-Apoptotic and Anti-Inflammatory Actions in Female Wistar Rats
Antimammary Tumour Effects of Calliandra portoricensis Fraction Via Pro-Apoptotic and Anti-Inflammatory Actions in Female Wistar Rats Open
Calliandra portoricensis (CP) is used in ethnomedicine to manage breast inflammation. We investigated the anti-mammary tumour effects of fraction from CP in rat model of mammary tumorigenesis induced with N methyl N nitrosourea (NMU) and b…
View article: FERMENTATION ENHANCES THE ANTIPROLIFERATIVE ACTIVITIES OF ANNONA SQUAMOSA SEED POLYSACCHARIDES ON HUMAN MCF-7 AND RHABDOMYOSARCOMA
FERMENTATION ENHANCES THE ANTIPROLIFERATIVE ACTIVITIES OF ANNONA SQUAMOSA SEED POLYSACCHARIDES ON HUMAN MCF-7 AND RHABDOMYOSARCOMA Open
Cancer is a primary cause of death globally and a significant public health concern. Polysaccharides are complex carbohydrates found abundantly in natural sources, including plants, and have attracted interest due to their possible health …
View article: Metagenomic Detection and Genetic Characterization of Human Sapoviruses among Children with Acute Flaccid Paralysis in Nigeria
Metagenomic Detection and Genetic Characterization of Human Sapoviruses among Children with Acute Flaccid Paralysis in Nigeria Open
Using a metagenomic sequencing approach on stool samples from children with Acute Flaccid Paralysis (AFP), we describe the genetic diversity of Sapoviruses (SaVs) in children in Nigeria. We identified six complete genome sequences and two …
View article: Whole genome sequencing unravels cryptic circulation of divergent dengue virus lineages in the rainforest region of Nigeria
Whole genome sequencing unravels cryptic circulation of divergent dengue virus lineages in the rainforest region of Nigeria Open
Dengue is often misclassified and underreported in Africa due to inaccurate differential diagnoses of nonspecific febrile illnesses such as malaria, sparsity of diagnostic testing and poor clinical and genomic surveillance. There are limit…
View article: Identification and genomic characterisation of known and novel highly divergent sapoviruses in frugivorous and insectivorous bats in Nigeria
Identification and genomic characterisation of known and novel highly divergent sapoviruses in frugivorous and insectivorous bats in Nigeria Open
Sapovirus (SaV) infections have been linked with moderate-to-severe acute gastroenteritis (AGE) in animals and humans and represent a significant risk to public health. SaVs from animals including pigs, chimpanzees, and rodents have been r…
View article: Viability of periodontal ligament cells in selected transport media for avulsed teeth
Viability of periodontal ligament cells in selected transport media for avulsed teeth Open
To compare the viability of periodontal ligament (PDL) cells stored in Hanks Balanced Salt Solution (HBSS) with those in readily available transport media over a variable period of time. Methods: Periodontal ligament cells harvested from p…
View article: 2183P The relevance of HFpEF in immunotherapy-induced myocarditis: An analysis of 65 patients
2183P The relevance of HFpEF in immunotherapy-induced myocarditis: An analysis of 65 patients Open
View article: Classic Human Astrovirus 4, 8, MLB-3 and likely new genotype 5 sub-lineage in stool samples of children with Acute Flaccid Paralysis (AFP) in Nigeria
Classic Human Astrovirus 4, 8, MLB-3 and likely new genotype 5 sub-lineage in stool samples of children with Acute Flaccid Paralysis (AFP) in Nigeria Open
Introduction: Acute viral gastroenteritis is a common illness especially in developing countries. Globally, the role of human astroviruses (HAstV) in gastroenteritis among children and elderly is well documented. But there exists a substan…
View article: Biochemical Constituents and Anticancer Activities of the Essential Oils of Lannea egregia Engl. & K. Krause
Biochemical Constituents and Anticancer Activities of the Essential Oils of Lannea egregia Engl. & K. Krause Open
Introduction: The Increase in cancer deaths has raised concerns among scientists to research on prospective anticancer agents. Lannea egregia was selected for this research because it has been identified to have ethnobotanical claims in re…
View article: Cytotoxic action of the leaves of Uvaria chamae P.Beauv. and Dicliptera paniculata (Forssk.) I.Darbysh. from Nigeria mediated through intrinsic apoptotic pathway induction in four cancer cell lines
Cytotoxic action of the leaves of Uvaria chamae P.Beauv. and Dicliptera paniculata (Forssk.) I.Darbysh. from Nigeria mediated through intrinsic apoptotic pathway induction in four cancer cell lines Open
Background: Over the years, the morbidity and mortality due to cancer have continued to increase worldwide. Plants are well utilized in Nigeria ethno-medicine for cancer treatment. However, scientific evidence, particularly at the molecula…
View article: Integrating network pharmacology and pharmacological evaluation to investigate the anticancer effects of Duranta erecta Linn. Verbenaceae in breast cancer
Integrating network pharmacology and pharmacological evaluation to investigate the anticancer effects of Duranta erecta Linn. Verbenaceae in breast cancer Open
Objective Breast cancer is the most prevalent type of cancer among women in sub-Saharan Africa. Efforts are being made to tackle the disease. However, numerous challenges are still reported. Duranta erecta showed medicinal relevance in dif…
View article: Anti-measles virus activity of 4-hydroxy-3-methoxy benzaldehyde (Vanillin) isolated from Xylopia aethiopica (Dunal) A. rich
Anti-measles virus activity of 4-hydroxy-3-methoxy benzaldehyde (Vanillin) isolated from Xylopia aethiopica (Dunal) A. rich Open
Xylopia aethiopica is a plant used ethnomedicinally for the treatment of several infections in Nigeria. This study was carried out to isolate the active compound(s) in Xylopia aethiopica and evaluate their anti-measles virus activity. The …
View article: Nearly Complete Genome Sequences of Type 2 Sabin-Like Polioviruses from Northern Nigerian Poliovirus Surveillance, 2016 to 2018
Nearly Complete Genome Sequences of Type 2 Sabin-Like Polioviruses from Northern Nigerian Poliovirus Surveillance, 2016 to 2018 Open
We sequenced 109 type 2 Sabin-like poliovirus isolates that had been collected from acute flaccid paralysis patients or healthy children in Nigeria. Understanding the genetic makeup of these viruses may contribute to polio eradication effo…
View article: Enterovirus species B isolates recovered from children with acute flaccid paralysis in Nigeria, 2010 and 2012
Enterovirus species B isolates recovered from children with acute flaccid paralysis in Nigeria, 2010 and 2012 Open
In 2010 and 2012, between June and October (the peak period of enterovirus circulation in Nigeria), 59 archived enterovirus isolates (recovered as part of the Acute Flaccid Paralysis surveillance program) were randomly selected and typed i…
View article: Emergence and spread of two SARS-CoV-2 variants of interest in Nigeria
Emergence and spread of two SARS-CoV-2 variants of interest in Nigeria Open
Identifying the dissemination patterns and impacts of a virus of economic or health importance during a pandemic is crucial, as it informs the public on policies for containment in order to reduce the spread of the virus. In this study, we…
View article: Human rotavirus VP4 and VP7 genetic diversity and detection of GII norovirus in Ibadan as Nigeria introduces rotavirus vaccine
Human rotavirus VP4 and VP7 genetic diversity and detection of GII norovirus in Ibadan as Nigeria introduces rotavirus vaccine Open
Objective This cross-sectional study investigated the circulating strains of rotavirus and screened for noravirus in Ibadan, Nigeria as the country introduces the rotavirus vaccine into its national immunization program. Methods Sixty-five…
View article: Human Bocavirus infection among children with respiratory tract infection in Ibadan, Nigeria
Human Bocavirus infection among children with respiratory tract infection in Ibadan, Nigeria Open
Background. Human Bocavirus (HBoV), which is an ssDNA virus of the family Parvoviridae , is responsible for 21.5 % of childhood respiratory tract infections (RTIs) annually. Among the four genotypes currently known, HBoV-1 has been associa…
View article: Circulation of hepatitis B virus genotype-E among outpatients in tertiary hospitals in the Niger-Delta region of Nigeria
Circulation of hepatitis B virus genotype-E among outpatients in tertiary hospitals in the Niger-Delta region of Nigeria Open
Introduction: Hepatitis B virus (HBV) infection continues to be a significant public health challenge globally, with higher disease burden in developing countries. HBV genotypes are associated with different geographical regions and clinic…
View article: Cytotoxicity Analysis of Nineteen Medicinal Plants Extracts on Breast Adenocarcinoma (MCF-7) and Rhabdomyosarcoma (RD) Cancer Cell Lines
Cytotoxicity Analysis of Nineteen Medicinal Plants Extracts on Breast Adenocarcinoma (MCF-7) and Rhabdomyosarcoma (RD) Cancer Cell Lines Open
The burden of cancer is alarmingly great on humans. However, the relevance of plants in combating cancer cannot be undermine. We joined the global search for anticancer agents from plants by screening nineteen (19) medicinal plant extracts…
View article: Multiple expansions of globally uncommon SARS-CoV-2 lineages in Nigeria
Multiple expansions of globally uncommon SARS-CoV-2 lineages in Nigeria Open
Disparities in SARS-CoV-2 genomic surveillance have limited our understanding of the viral population dynamics and may delay identification of globally important variants. Despite being the most populated country in Africa, Nigeria has rem…
View article: Cytotoxic Action of the Leaves of Uvaria Chamae P.Beauv. And Dicliptera Paniculata (Forssk.) I.Darbysh. From Nigeria Mediated Through Intrinsic Apoptotic Pathway Induction in Four Cancer Cell Lines
Cytotoxic Action of the Leaves of Uvaria Chamae P.Beauv. And Dicliptera Paniculata (Forssk.) I.Darbysh. From Nigeria Mediated Through Intrinsic Apoptotic Pathway Induction in Four Cancer Cell Lines Open
View article: Enterovirus Species B Isolates Recovered from Children with Acute Flaccid Paralysis in Nigeria, 2010 and 2012
Enterovirus Species B Isolates Recovered from Children with Acute Flaccid Paralysis in Nigeria, 2010 and 2012 Open
View article: Cytotoxic activity of crude extracts and fractions of African peach (nauclea latifolia smith) stem bark on two cancer cell lines
Cytotoxic activity of crude extracts and fractions of African peach (nauclea latifolia smith) stem bark on two cancer cell lines Open
View article: Yellow Fever in Nigeria: A Review of Past, Current, and Future Strides
Yellow Fever in Nigeria: A Review of Past, Current, and Future Strides Open
Since 1985, there has been resurgence of yellow fever in Africa with outbreaks occurring in more than 33 countries. From that time, thousands of cases have occurred in Nigeria which is the most populous country in Africa. Semi-urban and ur…
View article: In vitro antiviral activity of peptide-rich extracts from seven Nigerian plants against three non-polio enterovirus species C serotypes
In vitro antiviral activity of peptide-rich extracts from seven Nigerian plants against three non-polio enterovirus species C serotypes Open
Background As frequent viral outbreaks continue to pose threat to public health, the unavailability of antiviral drugs and challenges associated with vaccine development underscore the need for antiviral drugs discovery in emergent moments…