Ammar C. Al‐Rikabi
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View article: Plasmablastic lymphoma of the rectum: case report of a rare location and literature review
Plasmablastic lymphoma of the rectum: case report of a rare location and literature review Open
Plasmablastic lymphoma (PBL) is an aggressive and rare variant of diffuse large B-cell lymphoma, which is thought to occur in immunocompromised individuals, specifically HIV-positive patients. We report the case of a 27-year-old Saudi male…
View article: Prognostic significance of estrogen, progesterone and HER2 receptors’ status conversion following neoadjuvant chemotherapy in patients with locally advanced breast cancer: Results from a tertiary Cancer Center in Saudi Arabia
Prognostic significance of estrogen, progesterone and HER2 receptors’ status conversion following neoadjuvant chemotherapy in patients with locally advanced breast cancer: Results from a tertiary Cancer Center in Saudi Arabia Open
Background The prognostic impact of neoadjuvant chemotherapy (NAC) on the receptor expression status in patients with locally advanced breast cancer (LABC) is still not fully understood. We aimed to evaluate the changes in hormone (estroge…
View article: Pathological spectrum of endometrial biopsies in Saudi women with abnormal uterine bleeding
Pathological spectrum of endometrial biopsies in Saudi women with abnormal uterine bleeding Open
Awareness of the probable spectrum of endometrial histopathologies in the various ages is useful in guiding management. Endometrial biopsies are valuable in early detection of precancerous and cancerous endometrial lesions especially in wo…
View article: A case of dyschromatosis symmetrica hereditaria with an associated eyelid hemangioma
A case of dyschromatosis symmetrica hereditaria with an associated eyelid hemangioma Open
View article: The effect of low versus high tidal volume ventilation on inflammatory markers in animal model undergoing lung ventilation
The effect of low versus high tidal volume ventilation on inflammatory markers in animal model undergoing lung ventilation Open
Background and Aims: Mechanical ventilation (MV) with high tidal volume (Vt.) may induce or aggravate lung injury in critically ill patients. It might also cause an overwhelming systemic inflammation leading to acute lung injury (ALI), dif…
View article: Juvenile Trabecular Ossifying Fibroma (TrJOF) Orginating from Lateral Fronto-Orbital Bone with Secondary Aneurysmal Bone Cyst (ABC) Formation: Report of an Unusual Case and Literature Review
Juvenile Trabecular Ossifying Fibroma (TrJOF) Orginating from Lateral Fronto-Orbital Bone with Secondary Aneurysmal Bone Cyst (ABC) Formation: Report of an Unusual Case and Literature Review Open
Juvenile trabeculated Ossifying Fibroma (JTrOF) is commonly arising from the maxilla and the mandibular bones, while Psammomatoid Juvenile Ossifying Fibroma (PsJOF) commonly arises in the sinonasal and calvarial bones. In our paper, we des…
View article: Juvenile Trabecular Ossifying Fibroma (TrJOF) Orginating from Lateral Fronto-Orbital Bone with Secondary Aneurysmal Bone Cyst (ABC) Formation: Report of an Unusual Case and Literature Review
Juvenile Trabecular Ossifying Fibroma (TrJOF) Orginating from Lateral Fronto-Orbital Bone with Secondary Aneurysmal Bone Cyst (ABC) Formation: Report of an Unusual Case and Literature Review Open
Juvenile trabeculated Ossifying Fibroma (JTrOF) is commonly arising from the maxilla and the mandibular bones, while Psammomatoid Juvenile Ossifying Fibroma (PsJOF) commonly arises in the sinonasal and calvarial bones. In our paper, we des…
View article: MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the SMAD2/TGFβ pathway
MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the SMAD2/TGFβ pathway Open
View article: Sebaceous Gland Carcinoma with Misleading Clinical Appearance: A Case Report of an Eyelid Lesion
Sebaceous Gland Carcinoma with Misleading Clinical Appearance: A Case Report of an Eyelid Lesion Open
BACKGROUND Sebaceous gland carcinoma (SGC) is a rare malignant lesion that occurs on the eyelids. It is known to mimic other benign or malignant lesions in clinical presentation, such as a chalazion, basal cell carcinoma, and squamous cell…
View article: MicroRNA Expression Profiling on Paired Primary and Lymph Node Metastatic Breast Cancer Revealed Distinct microRNA Profile Associated With LNM
MicroRNA Expression Profiling on Paired Primary and Lymph Node Metastatic Breast Cancer Revealed Distinct microRNA Profile Associated With LNM Open
Breast cancer (BC) is the foremost cause of cancer-related deaths in women. BC patients are oftentimes presented with lymph node metastasis (LNM), which increases their risk of recurrence. Compelling data have recently implicated microRNAs…
View article: Primary extramedullary plasmacytoma of the eyelid conjunctiva – A case report and review of the literature
Primary extramedullary plasmacytoma of the eyelid conjunctiva – A case report and review of the literature Open
Extramedullary plasmacytomas (EMPs) are uncommon plasma cell tumors that develop in soft tissue as isolated tumors without osseous involvement while secondary lesions are associated with systemic multiple myeloma (MM). Primary extramedulla…
View article: Linear dermatomyofibroma over the nape of neck: a report of an unusual case and literature review
Linear dermatomyofibroma over the nape of neck: a report of an unusual case and literature review Open
Dermatomyofibroma is a rare cutaneous mesenchymal tumor of benign fibroblastic and myofibroblastic derivations. It predominantly affects young women, and it usually presents as a reddish-brown plaque or nodule, which is commonly located ov…
View article: Neoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B
Neoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B Open
Bone marrow stromal (Mesenchymal) stem cells (MSCs) are multipotent bone cells capable of differentiating into mesoderm-type cells, such as osteoblasts and adipocytes. Existing evidence suggests that transformation of MSCs gives rise to sa…
View article: Carnitine Supplementation Attenuates Sunitinib-Induced Inhibition of AMP-Activated Protein Kinase Downstream Signals in Cardiac Tissues
Carnitine Supplementation Attenuates Sunitinib-Induced Inhibition of AMP-Activated Protein Kinase Downstream Signals in Cardiac Tissues Open
View article: Gastric xanthelasma associated with hyperplastic polyp and mucosal erosions: report of an unusual case and literature review
Gastric xanthelasma associated with hyperplastic polyp and mucosal erosions: report of an unusual case and literature review Open
Gastric xanthelasma is a rare benign tumor-like lesion which is usually observed as an incidental finding due to its asymptomatic presentation. Grossly, it is a well-demarcated yellow-white plaque which is microscopically formed by cluster…
View article: Orbital T-cell lymphoma in youngest recorded patient – early diagnosis, management, and successful outcome: a case report and review of the literature
Orbital T-cell lymphoma in youngest recorded patient – early diagnosis, management, and successful outcome: a case report and review of the literature Open
View article: Letter in Reply: Appendiceal Inflammatory Myofibroblastic Tumor and HIV Infection, An Association Not To Be Missed
Letter in Reply: Appendiceal Inflammatory Myofibroblastic Tumor and HIV Infection, An Association Not To Be Missed Open
We read with interest the comments made by Al-Mendalawi on our publication, and we thank him for his useful comments and suggestions.
View article: Acrodermatitis Continua of Hallopeau with Bone Resorption in an 8-Year-Old Patient: A Case Report
Acrodermatitis Continua of Hallopeau with Bone Resorption in an 8-Year-Old Patient: A Case Report Open
Acrodermatitis continua of Hallopeau (ACH) is an uncommon inflammatory disease manifesting as sterile pustular eruption of the fingers and toes. The disease is of a chronic relapsing nature and is often refractory to treatment. With longst…
View article: Vascular sclerosing effects of bleomycin on cutaneous veins: a pharmacopathologic study on experimental animals
Vascular sclerosing effects of bleomycin on cutaneous veins: a pharmacopathologic study on experimental animals Open
This study showed that bleomycin-loaded liposomes were able to induce vasculitis and vascular occlusion without any toxicity or complications. It might be useful, hence, to treat patients suffering from Varicose veins and other ectatic vas…
View article: Predictive and prognostic significance of CD8+ tumor-infiltrating lymphocytes in patients with luminal B/HER 2 negative breast cancer treated with neoadjuvant chemotherapy
Predictive and prognostic significance of CD8+ tumor-infiltrating lymphocytes in patients with luminal B/HER 2 negative breast cancer treated with neoadjuvant chemotherapy Open
The immunobiology of breast cancer (BC) subtypes, including luminal cancer, remains unclear. Cluster of differentiation (CD)8+ tumor-infiltrating lymphocytes (TIL) are essential components of tumor-specific cellular adaptive imm…
View article: Molecular subtypes of breast carcinoma in Saudi Arabia
Molecular subtypes of breast carcinoma in Saudi Arabia Open
Luminal A tumor was the most common molecular subtype and HER2-positive was the least common. Most lobular carcinomas were luminal A tumors. Human epidermal growth factor receptor 2-positive and triple negative tumors had a higher histolog…