Baher Elgohari
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View article: Lessons Learned About Acute and Late Toxicity After Two Decades of Experience With Pancreatic SBRT
Lessons Learned About Acute and Late Toxicity After Two Decades of Experience With Pancreatic SBRT Open
Background: Stereotactic body radiotherapy (SBRT) is increasingly used to treat pancreatic cancer. However, data on acute morbidity, mortality, and late gastrointestinal toxicity risk following SBRT have not been reported. This study analy…
Prognostic Factors and Outcomes Associated With Neck Lymphedema in Head and Neck Cancer Survivors Open
Objectives The purpose of this study is to determine the predictors of neck lymphedema and to explore its association with symptoms and patient‐reported outcomes (PROs) in Head and Neck Cancer (HNC) patients who underwent non‐operative tre…
View article: OPC_RN_LN_dataset.csv
OPC_RN_LN_dataset.csv Open
Public anonymized data deposition for the publication: Spatially-aware clustering improves AJCC-8 risk stratification performance in oropharyngeal carcinomas; Guadalupe Canahuate, Andrew Wentzel, Abdallah S.R. Mohamed, Lisanne V. van Dijk,…
Changes in Apparent Diffusion Coefficient (ADC) in Serial Weekly MRI during Radiotherapy in Patients with Head and Neck Cancer: Results from the PREDICT-HN Study Open
Background: The PREDICT-HN study aimed to systematically assess the kinetics of imaging MR biomarkers during head and neck radiotherapy. Methods: Patients with intact squamous cell carcinoma of the head and neck were enrolled. Pre-, during…
Evaluation of different diffusion-weighted image techniques for head and neck radiation treatment: phantom and volunteer studies Open
Purpose To quantitatively compare and assess the geometric distortion and apparent diffusion coefficient (ADC) accuracy of conventional single-shot EPI (SSEPI)-DWI, readout segmentation of long variable echo-trains (RESOLVE)-DWI, and BLADE…
View article: Author Correction: Radiomics feature stability of open-source software evaluated on apparent diffusion coefficient maps in head and neck cancer
Author Correction: Radiomics feature stability of open-source software evaluated on apparent diffusion coefficient maps in head and neck cancer Open
The original version of this Article contained an error in the order of the Figures. Figures 1, 2, 3, 4 and 5 were published as Figures 5, 1, 2, 3, and 4 respectively. The original Figures 1, 2, 3, 4 and 5 and accompanying legends appear b…
Radiomics feature stability of open-source software evaluated on apparent diffusion coefficient maps in head and neck cancer Open
Radiomics is a promising technique for discovering image based biomarkers of therapy response in cancer. Reproducibility of radiomics features is a known issue that is addressed by the image biomarker standardisation initiative (IBSI), but…
Computed Tomography Radiomics Kinetics as Early Imaging Correlates of Osteoradionecrosis in Oropharyngeal Cancer Patients Open
Osteoradionecrosis (ORN) is a major side-effect of radiation therapy in oropharyngeal cancer (OPC) patients. In this study, we demonstrate that early prediction of ORN is possible by analyzing the temporal evolution of mandibular subvolume…
Circulating tumour cell and cell-free DNA kinetics during radiotherapy in patients with intact head and neck squamous cell carcinoma Open
Head and neck squamous cell carcinoma (HNSCC) treatment response relies heavily on macroscopic clinical findings. Blood monitoring of circulating markers during treatment may improve earlier detection of responders versus non-responders du…
Discovering early imaging biomarkers of osteoradionecrosis in oropharyngeal cancer by characterization of temporal changes in computed tomography mandibular radiomic features Open
Osteoradionecrosis (ORN) is a major side-effect of radiation therapy in oropharyngeal cancer (OPC) patients. In this study, we demonstrate that early prediction of ORN is possible by analyzing the temporal evolution of mandibular subvolume…
Tobacco exposure as a major modifier of oncologic outcomes in human papillomavirus (HPV) associated oropharyngeal squamous cell carcinoma Open
Background The incidence of oropharyngeal squamous cell carcinoma (OPSCC) in the US is rapidly increasing, driven largely by the epidemic of human papillomavirus (HPV)-mediated OPSCC. Although survival for patients with HPV mediated OPSCC …
Tobacco exposure as a major modifier of oncologic outcomes in Human PapillomaVirus (HPV) associated oropharyngeal squamous cell carcinoma Open
Background: The incidence of oropharyngeal squamous cell carcinoma (OPSCC) in the US is rapidly increasing, driven largely by the epidemic of human papillomavirus (HPV)-mediated OPSCC. Although survival for patients with HPV mediated OPSCC…
Precision association of lymphatic disease spread with radiation-associated toxicity in oropharyngeal squamous carcinomas Open
Purpose Using a cohort of 582 head and neck cancer patients with nodal disease, we employed clustering over a novel graph-based geometrical representation of lymph node spread in order to identify groups of similar patients. We show that t…
Tobacco exposure as a major modifier of oncologic outcomes in Human PapillomaVirus (HPV) associated oropharyngeal squamous cell carcinoma Open
Background: The incidence of oropharyngeal squamous cell carcinoma (OPSCC) in the US is rapidly increasing, driven largely by the epidemic of human papillomavirus (HPV)-mediated OPSCC. Although survival for patients with HPV mediated OPSCC…
Tobacco exposure as a major modifier of oncologic outcomes in Human PapillomaVirus (HPV) associated oropharyngeal squamous cell carcinoma Open
Background: The incidence of oropharyngeal squamous cell carcinoma (OPSCC) in the US is rapidly increasing, driven largely by the epidemic of human papillomavirus (HPV)-mediated OPSCC. Although survival for patients with HPV mediated OPSCC…
Longitudinal Characterization of the Tumoral Microbiome during Radiotherapy in HPV-associated Oropharynx Cancer Open
Purpose To describe the baseline and serial tumor microbiome in HPV-associated oropharynx cancer (OPC) over the course of radiotherapy (RT). Methods Patients with newly diagnosed HPV-associated OPC treated with definitive radiotherapy +/- …
18FDG Positron Emission Tomography Mining for Metabolic Imaging Biomarkers of Radiation-induced Xerostomia in Patients with Oropharyngeal Cancer Open
Purpose Head and neck cancers (HNC) radiotherapy (RT) is associated with inevitable injury to parotid glands and subsequent xerostomia. We investigated the utility of standardized uptake values (SUV) derived from routinely performed 18-flu…