A. Bertolotti
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Acceptance of chikungunya vaccination: a rapid survey in Reunion island during an epidemic Open
During the 2025 chikungunya outbreak in Réunion Island, two vaccines-IXCHIQ (live-attenuated) and VIMKUNYA (virus-like particle)-received European Union authorization; a local campaign began in April 2025 and was temporarily adjusted for o…
Boosting Human Papillomavirus Vaccination Rates: Protocol for a Randomized Controlled Trial of Awareness Interventions in Réunion Island Open
Background Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide and imposes a significant public health burden. In 2019, HPV was responsible for approximately 620,000 cancer cases in women, 70,000 in men, …
Successful Treatment of Dupilumab in Two Cases of Refractory Kimura's Disease Open
Kimura disease (KD) is a chronic inflammatory disorder characterized by subcutaneous nodules, cervical lymphadenopathy, hypereosinophilia, and elevated IgE levels. Treatment options are limited. We report two cases of refractory KD success…
Boosting Human Papillomavirus Vaccination Rates: Protocol for a Randomized Controlled Trial of Awareness Interventions in Réunion Island (Preprint) Open
BACKGROUND Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide and imposes a significant public health burden. In 2019, HPV was responsible for approximately 620,000 cancer cases in women, 70,000 in men, …
High prevalence and incidence of systemic sclerosis in Reunion Island, a French multi-ethnical and tropical territory Open
Our study revealed high prevalence and incidence of SSc in Reunion Island which is consistent with the frequently described higher frequency among patients of African origin.
The Role of Dermoscopy in Diagnosing Xeroderma Pigmentosum: A Practical Tool in Low-resource Settings Open
is missing (Research letter)
Plasmonic nanophotothermal therapy: Destruction of 500 mm <sup>3</sup> subcutaneous human basal cell carcinoma with gold nanoparticles and near infrared laser Open
Significance Multilesional basal cell carcinoma (BCC) are spread on sun exposed skin areas, including arms, face and back. The first‐line treatment remains the surgical resection or Mohs surgery. Despite its high complexity, Mohs surgery i…
Mucocutaneous Manifestations in Patients with Dengue Fever: From the EPIDENGUE Cohort on Reunion Island Open
Nearly 4 billion people live in a dengue risk area worldwide. The prevalence of dengue-related mucocutaneous manifestations and their association with severe dengue differ across studies. The aim of the study was to describe the characteri…
Blueish indurated nodule of the tongue in a teenager Open
A 14-year-old boy with no prior medical history, presented with a 2-month history of a painless tongue lesion and a 1-month history of a painful left pelvic swelling, associated with functional limitation. Clinical examination revealed an …
Syphilis still exists Open
The work of Nicolaidou et al.1 reports an increase in syphilis cases between two periods: 2 years after the outbreak of the COVID pandemic and 2 years before the pandemic. The observed a difference was revealed in the number of men having …
PRESOLRE: study protocol for a primary school-based, cluster randomised controlled trial of three sun exposure risk prevention strategies on Reunion Island Open
Introduction Reunion Island, a French overseas department, is located in the southern hemisphere, close to the Capricorn tropic. This island has a multicultural and multiethnic population of 860 000 inhabitants, a quarter of whom are at hi…
Promoting clinical research in community-based practice: Threats and opportunities Open
Editorial Material
Atypical fixed drug eruption in confetti due to paracetamol Open
Dear Editor, Fixed drug eruption (FDE) is a rare recurrent drug eruption occurring at the same anatomical locations after readministration of an offending substance that is taken systemically. Persistent postinflammatory hyperpigmentation …
Diagnostic performance of the WHO definition of probable dengue within the first 5 days of symptoms on Reunion Island Open
The relevance of the World Health Organization (WHO) criteria for defining probable dengue had not yet been evaluated in the context of dengue endemicity on Reunion Island. The objective of this retrospective diagnostic study was to evalua…
Harness risk stratification of diabetic patients with dengue in a cohort study Open
Together, these data highlight the role of diabetes mellitus in the progression from dengue to SD through higher severity per se or the event of MODS.
Plasmonic nanophotothermal therapy for the treatment of basal cell carcinoma with gold nanoparticles Open
Background Basal cell carcinoma (BCC) is the most common form of skin cancer, typically developing in sun‐exposed areas such as the face. Surgery is the treatment of choice, with a overall good prognosis. However, some scars can be unsight…
Clinical and Epidemiological Aspects of Acute Q Fever in Reunion Island over Fourteen Years: A Retrospective Cohort Study Open
The clinical characteristics and epidemiology of Q fever in the Tropics are poorly described. We performed a retrospective cohort study of hospitalized cases between 2004 and 2017 in Reunion Island. Acute Q fever was defined in presence of…
Human Papillomavirus (HPV) Infections Among Participants Undergoing Chlamydia trachomatis Testing in Reunion Island (RUN-SurV-HPV Study): Protocol for a Prevalence Study Open
Background Infection by human papillomavirus (HPV) induces various cancers, mainly cervical cancer but also anal and pharyngeal cancers. Reunion Island is a French department in the Indian Ocean. Due to the history of its settlement, the i…
Descriptive and comparative analysis of mucocutaneous manifestations in patients with dengue fever: A prospective study Open
Background Dengue is an arbovirosis affecting nearly 4 billion people worldwide. Since 2018, dengue has been re‐emerging in Reunion Island. The incidence of mucocutaneous manifestations varies according to the studies and is generally call…
PRESOLRE: Study protocol for a primary school-based, cluster randomised controlled trial of three sun exposure risk prevention strategies on Reunion Island Open
Introduction : Reunion Island, a French overseas department, is located in the southern hemisphere, close to the Capricorn tropic in the same range of latitudes as Australia. This island has a multi-cultural and multi-ethnicpopulation of 8…
C-reactive protein: An easy marker for early differentiation between leptospirosis and dengue fever in endemic area Open
In tropical regions, leptospirosis and dengue fever (DF) are infectious diseases of epidemiological importance and have overlapping symptomatic features. The objective of this study was to identify the factors associated to diagnosing lept…