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View article: Allogeneic hematopoietic cell transplant in cutaneous T-cell lymphomas: recommendations from the EBMT PH&G Committee
Allogeneic hematopoietic cell transplant in cutaneous T-cell lymphomas: recommendations from the EBMT PH&G Committee Open
This manuscript provides expert recommendations on the role of allogeneic hematopoietic cell transplantation (allo-HCT) for cutaneous T-cell lymphoma (CTCL), specifically Mycosis Fungoides (MF) and Sezary Syndrome (SS). Critical aspects su…
View article: Allogeneic haematopoietic cell transplant in cutaneous T‐cell lymphomas: Recommendations from the <scp>EBMT PH</scp>&G Committee
Allogeneic haematopoietic cell transplant in cutaneous T‐cell lymphomas: Recommendations from the <span>EBMT PH</span>&G Committee Open
This manuscript provides expert recommendations on the role of allogeneic haematopoietic cell transplantation (allo‐HCT) for cutaneous T‐cell lymphoma (CTCL), specifically mycosis fungoides (MF) and Sezary syndrome (SS). Critical aspects s…
View article: Mycosis Fungoides in Pediatric Patients Revealed by Recalcitrant Psoriasiform Palmoplantar Keratoderma
Mycosis Fungoides in Pediatric Patients Revealed by Recalcitrant Psoriasiform Palmoplantar Keratoderma Open
Mycosis fungoides is a cutaneous T‐cell lymphoma with a classically relatively good prognosis, mostly diagnosed in men over the age of 50. It classically manifests as erythematosquamous plaques, but can take a variety of forms. Here we des…
View article: Atypical Gamma‐Delta‐Positive T‐Cell Lymphoproliferation With Clinical Features of Lymphomatoid Papulosis in Three Children
Atypical Gamma‐Delta‐Positive T‐Cell Lymphoproliferation With Clinical Features of Lymphomatoid Papulosis in Three Children Open
Primary cutaneous gamma‐delta T‐cell lymphoma has been described as an aggressive entity with a poor prognosis. However, gamma‐delta T‐cell receptor expression has been described in various types of skin lymphoproliferations. Paediatric ca…
View article: Lichenoid graft‐versus‐host disease shows a high interferon score, with <scp>IFNAR1</scp> inhibition preventing skin inflammation
Lichenoid graft‐versus‐host disease shows a high interferon score, with <span>IFNAR1</span> inhibition preventing skin inflammation Open
Background Chronic cutaneous graft‐versus‐host disease (ccGVHD) is a debilitating complication of allogeneic haematopoietic stem cell transplantation, manifesting as either sclerotic or lichenoid eruptions (lGVHD). Although frequent, the p…
View article: The CD39/CD73/Adenosine and NAD/CD38/CD203a/CD73 Axis in Cutaneous T-Cell Lymphomas
The CD39/CD73/Adenosine and NAD/CD38/CD203a/CD73 Axis in Cutaneous T-Cell Lymphomas Open
Cutaneous T-cell lymphoma (CTCL), characterized by malignant T-cell proliferation primarily in the skin, includes subtypes such as mycosis fungoides (MF) and Sézary syndrome (SS). The tumor microenvironment (TME) is central to their pathog…
View article: Hypereosinophilia and Hypereosinophilic Syndromes: First Findings From a Nationwide Multicenter Cohort
Hypereosinophilia and Hypereosinophilic Syndromes: First Findings From a Nationwide Multicenter Cohort Open
Background Hypereosinophilic syndromes (HES) are a heterogenous group of eosinophilic disorders. To date, only retrospective studies of limited sample‐size and/or follow‐up duration are available. Methods The COHESion study is a national p…
View article: Real-life efficacy of immunotherapy for Sézary syndrome: a multicenter observational cohort study
Real-life efficacy of immunotherapy for Sézary syndrome: a multicenter observational cohort study Open
[This corrects the article DOI: 10.1016/j.eclinm.2024.102679.].
View article: Recurrent primary cutaneous marginal zone lymphoma: a comparative study of initial tumours, recurrences, and outcomes in 61 patients
Recurrent primary cutaneous marginal zone lymphoma: a comparative study of initial tumours, recurrences, and outcomes in 61 patients Open
Aims Primary cutaneous marginal zone lymphoma (PCMZL) is considered a lymphoproliferative disorder (International Consensus Classification, ICC) or an overt lymphoma (WHO‐HAEM5). Seeking evidence for a reactive process or true lymphoma, we…
View article: Targeting TGF-β Activation in Cutaneous T-Cell Lymphomas
Targeting TGF-β Activation in Cutaneous T-Cell Lymphomas Open
Cutaneous T-cell lymphomas (CTCL) are T-cell malignancies of the skin. In advanced-stage CTCL, the remissions are generally rare and short, and overall survival <5 years. Allogeneic stem cell transplantation may lead to long-term remission…
View article: Myopathy related to chronic Graft‐Versus‐Host Disease: From clinic to histological & immunological characterization by imaging mass cytometry
Myopathy related to chronic Graft‐Versus‐Host Disease: From clinic to histological & immunological characterization by imaging mass cytometry Open
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View article: Targeting CCR4 with mogamulizumab in refractory CD3-CD4<sup>+</sup> lymphocytic-variant hypereosinophilic syndrome
Targeting CCR4 with mogamulizumab in refractory CD3-CD4<sup>+</sup> lymphocytic-variant hypereosinophilic syndrome Open
Not available.
View article: Sezary syndrome revealed by PD‐L1 blockade for tumor stage mycosis fungoides
Sezary syndrome revealed by PD‐L1 blockade for tumor stage mycosis fungoides Open
Cutaneous T‐cell lymphomas (CTCLs) are unique non‐Hodgkin lymphomas due to the proliferation of skin‐homing T cells. Sezary syndrome (SS), a subtype of CTCL, typically presents as erythroderma with specific blood involvement and seldomly e…
View article: CD39 is Expressed by a Wide Range of Cutaneous T-Cell Lymphomas
CD39 is Expressed by a Wide Range of Cutaneous T-Cell Lymphomas Open
CD39, an ectoenzyme in the immunosuppressive CD39/CD73/adenosine pathway, known to promote solid tumour outgrowth and spreading, was investigated in both skin and blood compartments of cutaneous T cell lymphomas. CD39 was overexpressed by …
View article: Mogamulizumab for Refractory CD3-CD4+ Lymphocytic-Variant Hypereosinophilic Syndrome
Mogamulizumab for Refractory CD3-CD4+ Lymphocytic-Variant Hypereosinophilic Syndrome Open
OCS Introduction. Lymphocytic hypereosinophilic syndrome (L-HES) is an indolent T-cell lymphoproliferative disorder characterized by chronic blood hypereosinophilia and eosinophil-related organ damage secondary to the production of eosinop…
View article: Severe relapses of cutaneous T‐cell lymphoma after treatment of chronic graft‐versus‐host disease with ruxolitinib
Severe relapses of cutaneous T‐cell lymphoma after treatment of chronic graft‐versus‐host disease with ruxolitinib Open
The data that support the findings of this study are available from the corresponding author upon reasonable request.
View article: Skin involvement in systemic lymphoma of follicular helper T‐cell origin: A cohort study of 57 patients
Skin involvement in systemic lymphoma of follicular helper T‐cell origin: A cohort study of 57 patients Open
Background Angioimmunoblastic T‐cell lymphoma (AITL) is one of the most frequent peripheral T‐cell lymphomas (PTCL) in western countries. Skin involvement is common and may reveal the malignancy. Despite its frequency, skin involvement in …
View article: Primary cutaneous follicle centre lymphoma with secondary systemic evolution
Primary cutaneous follicle centre lymphoma with secondary systemic evolution Open
Primary cutaneous follicle centre lymphomas (PCFCLs) are cutaneous proliferation of centrocytes and centroblasts, with a generally indolent evolution. Secondary systemic spread of disease is a rare event, which significantly impairs progno…
View article: Serum infliximab levels and clinical response in hidradenitis suppurativa
Serum infliximab levels and clinical response in hidradenitis suppurativa Open
Background Infliximab (IFX) is a chimeric immunoglobulin G‐1κ monoclonal antibody that neutralises the biologic activity of tumour necrosis factor‐α, and has shown efficacy (off‐label) for the treatment of severe hidradenitis suppurativa (…
View article: Supplementary Data from Radiotherapy Eradicates Malignant T Cells and Is Associated with Improved Survival in Early-Stage Mycosis Fungoides
Supplementary Data from Radiotherapy Eradicates Malignant T Cells and Is Associated with Improved Survival in Early-Stage Mycosis Fungoides Open
Figure S4
View article: Supplementary Data from Radiotherapy Eradicates Malignant T Cells and Is Associated with Improved Survival in Early-Stage Mycosis Fungoides
Supplementary Data from Radiotherapy Eradicates Malignant T Cells and Is Associated with Improved Survival in Early-Stage Mycosis Fungoides Open
Figure S4
View article: Supplementary Data from Radiotherapy Eradicates Malignant T Cells and Is Associated with Improved Survival in Early-Stage Mycosis Fungoides
Supplementary Data from Radiotherapy Eradicates Malignant T Cells and Is Associated with Improved Survival in Early-Stage Mycosis Fungoides Open
Figure S3