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View article: Proposal NFDI4Chem 2025-2030 In the National Research Data Infrastructure (NFDI) — Our Vision: All Chemists Publish FAIR Data
Proposal NFDI4Chem 2025-2030 In the National Research Data Infrastructure (NFDI) — Our Vision: All Chemists Publish FAIR Data Open
The first funding period of NFDI4Chem established a robust foundation for research data management (RDM) in chemistry by promoting FAIR data principles and creating a cohesive infrastructure to capture well-annotated data early in the lab …
View article: Double trouble: The synergistic threat of environmental stressors and pesticide mixtures
Double trouble: The synergistic threat of environmental stressors and pesticide mixtures Open
Halting biodiversity loss demands a clear understanding of how multiple stressors interact across levels of biological organization. Here, we investigate these interactions at the individual level using Daphnia magna as a model species. We…
View article: Chemical mixture risk drivers and their heterogeneity in European freshwaters
Chemical mixture risk drivers and their heterogeneity in European freshwaters Open
Chemical pollution of aquatic environments involves diverse substance combinations that can provoke combined biological and toxicological effects even when individual concentrations remain below effect thresholds. Multiple efforts are ongo…
View article: Exposure to marine contaminant mixtures with different toxicity drivers reduces microzooplankton diversity
Exposure to marine contaminant mixtures with different toxicity drivers reduces microzooplankton diversity Open
Marine surface waters contain complex mixtures of chemicals that can adversely affect microzooplankton. There is a lack of toxicity data for this organism group, and we used two different methodologies to fill this gap. We tested the toxic…
View article: Nontarget and Suspect Screening of Fluorinated Ionic Liquids and PFAS in European Wastewaters Using Supercritical Fluid Chromatography
Nontarget and Suspect Screening of Fluorinated Ionic Liquids and PFAS in European Wastewaters Using Supercritical Fluid Chromatography Open
Per- and polyfluoroalkyl substances (PFAS) and fluorinated ionic liquids were investigated in municipal effluents from 30 wastewater treatment plants (WWTPs) across 15 European countries using supercritical fluid chromatography–high-resolu…
View article: Nontarget and Suspect Screening of Fluorinated Ionic Liquids and PFAS in European Wastewaters Using Supercritical Fluid Chromatography
Nontarget and Suspect Screening of Fluorinated Ionic Liquids and PFAS in European Wastewaters Using Supercritical Fluid Chromatography Open
Per- and polyfluoroalkyl substances (PFAS) and fluorinated ionic liquids were investigated in municipal effluents from 30 wastewater treatment plants (WWTPs) across 15 European countries using supercritical fluid chromatography-high-resolu…
View article: Exploring Domestic Discharge Patterns in Wastewater through LC-HRMS Screening and Temporal Clustering
Exploring Domestic Discharge Patterns in Wastewater through LC-HRMS Screening and Temporal Clustering Open
Wastewater influent contains valuable epidemiological information, but the complexity of the wastewater matrix poses challenges for data interpretation and linking signals to human exposure. This study aims to analyze daily discharge patte…
View article: Current emission vs. legacy organic pollutants: Assessing the extent to which the eco-exposome of caged fish reflects external exposure
Current emission vs. legacy organic pollutants: Assessing the extent to which the eco-exposome of caged fish reflects external exposure Open
The eco-exposome represents the totality of chemicals present in an organism. To understand how internal exposure of fish relates to chemicals originating from external media (water, sediment), we conducted a 21-d caging study using fathea…
View article: Fingerprints of micropollutants under baseflow and event discharge conditions: analysing gradients along two urban streams
Fingerprints of micropollutants under baseflow and event discharge conditions: analysing gradients along two urban streams Open
This study presents the results from a monitoring campaign at two urban streams with multiple monitoring sites along an increased urban gradient, carried out in April to August 2022. The aim of the monitoring campaign was to identify press…
View article: Aquatic ecosystems as a final receptor of atmospheric organic particulate-bound pollutants: a plea for the integration of aquatic ecotoxicology into the risk assessment of air pollution
Aquatic ecosystems as a final receptor of atmospheric organic particulate-bound pollutants: a plea for the integration of aquatic ecotoxicology into the risk assessment of air pollution Open
Background Air pollution has detrimental effects on human health and is estimated to cause millions of premature deaths worldwide each year. The effects of polluted air on human health, ranging from respiratory and cardiovascular disorders…
View article: Assessment of chemical footprints of hydrophobic pesticide/biocide contamination in western Kenya using polydimethylsiloxane silicone passive samplers
Assessment of chemical footprints of hydrophobic pesticide/biocide contamination in western Kenya using polydimethylsiloxane silicone passive samplers Open
In a previous study based on LC-HRMS screening of pesticides and other organic micropollutants, it was shown that pesticide pollution of water resources in western Kenya poses a significant risk to aquatic and human health. In the current …
View article: Non-Target Screening of Fluorinated Ionic Liquids and PFAS in European Wastewaters Using Supercritical Fluid Chromatography
Non-Target Screening of Fluorinated Ionic Liquids and PFAS in European Wastewaters Using Supercritical Fluid Chromatography Open
Per- and polyfluoroalkyl substances (PFAS) and fluorinated ionic liquids are increasingly recognized as persistent environmental contaminants. In this study, municipal effluent samples from 30 wastewater treatment plants (WWTPs) across 15 …
View article: Chemical stress assessment in large rivers using the average biomarker response approach with caged fish in situ: a case study on the Danube River in Novi Sad (Serbia)
Chemical stress assessment in large rivers using the average biomarker response approach with caged fish in situ: a case study on the Danube River in Novi Sad (Serbia) Open
Background Exposure assessment of aquatic biota to complex chemical mixtures from anthropogenic sources and evaluating potential impacts are crucial for mitigating toxic pressure and improving ecological status. The study focused on a sect…
View article: Seamless forward assessment of toxic risks in river networks for mixtures of chemicals originating from wastewater treatment plant effluents
Seamless forward assessment of toxic risks in river networks for mixtures of chemicals originating from wastewater treatment plant effluents Open
Chemicals in the aquatic environment can be harmful to biota and may cause toxic risks to the aquatic ecosystems. A high number of these chemicals originate from point sources (households, manufacturing and industries). A subset of the sub…
View article: Following the Mixtures of Organic Micropollutants with <i>In Vitro</i> Bioassays in a Large Lowland River from Source to Sea
Following the Mixtures of Organic Micropollutants with <i>In Vitro</i> Bioassays in a Large Lowland River from Source to Sea Open
Human-impacted rivers often contain a complex mixture of organic micropollutants, including pesticides, pharmaceuticals and industrial compounds, along with their transformation products. Combining chemical target analysis for exposure wit…
View article: High-Throughput Effect-Directed Analysis of Androgenic Compounds in Hospital Wastewater: Identifying Effect Drivers through Non-Target Screening Supported by Toxicity Prediction
High-Throughput Effect-Directed Analysis of Androgenic Compounds in Hospital Wastewater: Identifying Effect Drivers through Non-Target Screening Supported by Toxicity Prediction Open
The increasing number of contaminants released into the environment necessitates innovative strategies for their detection and identification, particularly in complex environmental matrices like hospital wastewater. Hospital effluents cont…
View article: Bacterial community responses to micropollutants in chemically stressed small rivers in Kenya using environmental DNA
Bacterial community responses to micropollutants in chemically stressed small rivers in Kenya using environmental DNA Open
The responses of bacterial communities to changing environmental conditions are manifold but can include structural as well as functional alterations depending on the environmental stressors and toxic chemicals they are exposed to (e.g. ph…
View article: Occurrence and potential risk of steroid hormones in selected surface water and wastewater treatment plants in western Kenya
Occurrence and potential risk of steroid hormones in selected surface water and wastewater treatment plants in western Kenya Open
Steroid hormones are significant contributors to endocrine disruption, affecting the hormonal functions of both humans and aquatic organisms. However, data on their occurrence and risks in fresh water systems particularly in low- and middl…
View article: Mixtures of toxic organic micropollutants compromise the safety of water resources in urban agglomerations in low- and medium-income countries: The example of Lahore, Pakistan
Mixtures of toxic organic micropollutants compromise the safety of water resources in urban agglomerations in low- and medium-income countries: The example of Lahore, Pakistan Open
Contamination of water resources with mixtures of organic micropollutants (OMP) including pesticides, pharmaceuticals, and industrial chemicals is a serious threat to aquatic organisms and human health. Long-term exposure to such pollutant…
View article: AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers
AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers Open
The vast amount of registered chemicals leads to a high diversity of substances occurring in the environment and the creation of new substances outpaces chemical risk assessment as well as monitoring strategies. Hence, risk assessment stra…
View article: Co-occurrence and spatial distribution of organic micropollutants in surface waters of the River Aconcagua and Maipo basins in Central Chile
Co-occurrence and spatial distribution of organic micropollutants in surface waters of the River Aconcagua and Maipo basins in Central Chile Open
Organic Micropollutants (OMPs) might pose significant risks to aquatic life and have potential toxic effects on humans. These chemicals typically occur as complex mixtures rather than individually. Information on their co-occurrence and th…
View article: Mixtures of organic micropollutants exacerbated in vitro neurotoxicity of prymnesins and contributed to aquatic toxicity during a toxic algal bloom
Mixtures of organic micropollutants exacerbated in vitro neurotoxicity of prymnesins and contributed to aquatic toxicity during a toxic algal bloom Open
Prymnesins produced by an algal bloom of Prymnesium parvum led to the death of several hundred tons of freshwater fish in the Oder River in summer 2022. We investigated effects on aquatic life and human cell lines from exposure to extracts…
View article: Pesticide residues and polyphenols in urine – A combined LC-HRMS screening to reveal intake patterns
Pesticide residues and polyphenols in urine – A combined LC-HRMS screening to reveal intake patterns Open
Human exposure to pesticides in the general population occurs mainly through food consumption. However, specific dietary habits or food products that contribute to pesticide exposure are often unknown. In this study, we propose a combined …