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View article: Effective spot size parameters for Acuros dose calculation algorithm using enhanced leaf modelling: Estimation based on small rectangular MLC fields
Effective spot size parameters for Acuros dose calculation algorithm using enhanced leaf modelling: Estimation based on small rectangular MLC fields Open
Background and Purpose Small field dosimetry plays a critical role in stereotactic radiotherapy, particularly for elongated fields shaped by multileaf collimators (MLCs). This study aims to optimize the Effective Spot Size (ESS) parameters…
View article: A Time-Series Approach for Machine Learning-Based Patient-Specific Quality Assurance of Radiosurgery Plans
A Time-Series Approach for Machine Learning-Based Patient-Specific Quality Assurance of Radiosurgery Plans Open
Stereotactic radiosurgery (SRS) for multiple brain metastases can be delivered with a single isocenter and non-coplanar arcs, achieving highly conformal dose distributions at the cost of extreme modulation of treatment machine parameters. …
View article: Small elongated MLC fields: Novel equivalent square field formula and output factors
Small elongated MLC fields: Novel equivalent square field formula and output factors Open
Purpose This study evaluates different approaches for estimating the equivalent square field size (ESF) to derive the Output Correction Factors (OCF) according to the IAEA TRS‐483 protocol, for small fields, focusing on rectangular fields …
View article: Evaluation of ion recombination and polarity effect on photon depth dose measurements using mini‐ and micro‐ion chamber
Evaluation of ion recombination and polarity effect on photon depth dose measurements using mini‐ and micro‐ion chamber Open
Purpose To investigate the effect of ion recombination () and polarity () correction factors on percentage depth dose (PDD) curves for three ion chambers, using flat and flattening filter free (FFF) beams, across different broad field size…
View article: Optimization of Replanning Processes for Volumetric Modulated Arc Therapy Plans at Risk of QA Failure Predicted by a Machine Learning Model
Optimization of Replanning Processes for Volumetric Modulated Arc Therapy Plans at Risk of QA Failure Predicted by a Machine Learning Model Open
Patient-specific quality assurance (PSQA) procedures ensure the safe delivery of volumetric modulated arc therapy (VMAT) plans. PSQA requires extensive time and resources and may cause treatment delays if replanning is needed due to failur…
View article: Machine learning and lean six sigma for targeted patient-specific quality assurance of volumetric modulated arc therapy plans
Machine learning and lean six sigma for targeted patient-specific quality assurance of volumetric modulated arc therapy plans Open
ML and Lean Six Sigma have been implemented in clinical practice enabling a targeted measurement-based PSQA approach for plans at risk of failure to improve overall quality and patient safety.
View article: Dataset related to article "Can STEreotactic Body Radiation Therapy (SBRT) Improve the Prognosis of Unresectable Locally Advanced Pancreatic Cancer? Long-Term Clinical Outcomes, Toxicity and Prognostic Factors on 142 Patients (STEP Study) "
Dataset related to article "Can STEreotactic Body Radiation Therapy (SBRT) Improve the Prognosis of Unresectable Locally Advanced Pancreatic Cancer? Long-Term Clinical Outcomes, Toxicity and Prognostic Factors on 142 Patients (STEP Study) " Open
<p>This record contains raw data related to article “Can STEreotactic Body Radiation Therapy (SBRT) Improve the Prognosis of Unresectable Locally Advanced Pancreatic Cancer? Long-Term Clinical Outcomes, Toxicity and Prognostic …
View article: Can STEreotactic Body Radiation Therapy (SBRT) Improve the Prognosis of Unresectable Locally Advanced Pancreatic Cancer? Long-Term Clinical Outcomes, Toxicity and Prognostic Factors on 142 Patients (STEP Study)
Can STEreotactic Body Radiation Therapy (SBRT) Improve the Prognosis of Unresectable Locally Advanced Pancreatic Cancer? Long-Term Clinical Outcomes, Toxicity and Prognostic Factors on 142 Patients (STEP Study) Open
Aim: The gold standard of care for pancreatic adenocarcinoma is the integrated treatment of surgery and chemotherapy (ChT), but about 50% of patients present with unresectable disease. Our study evaluated the efficacy in terms of local con…
View article: Twenty Years of Advancements in a Radiotherapy Facility: Clinical Protocols, Technology, and Management
Twenty Years of Advancements in a Radiotherapy Facility: Clinical Protocols, Technology, and Management Open
Background: Hypo-fractionation can be an effective strategy to lower costs and save time, increasing patient access to advanced radiation therapy. To demonstrate this potential in practice within the context of temporal evolution, a twenty…
View article: Predictors of Patient-Reported Incontinence at Adjuvant/Salvage Radiotherapy after Prostatectomy: Impact of Time between Surgery and Radiotherapy
Predictors of Patient-Reported Incontinence at Adjuvant/Salvage Radiotherapy after Prostatectomy: Impact of Time between Surgery and Radiotherapy Open
Background: Baseline urinary incontinence (UI) strongly modulates UI recovery after adjuvant/salvage radiotherapy (ART/SRT), inducing clinicians to postpone it “as much as possible”, maximizing UI recovery but possibly reducing efficacy. T…
View article: Pre-clinical Research on Bladder Toxicity After Radiotherapy for Pelvic Cancers: State-of-the Art and Challenges
Pre-clinical Research on Bladder Toxicity After Radiotherapy for Pelvic Cancers: State-of-the Art and Challenges Open
Despite the dramatic advancements in pelvic radiotherapy, urinary toxicity remains a significant side-effect. The assessment of clinico-dosimetric predictors of radiation cystitis (RC) based on clinical data has improved substantially over…
View article: A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats
A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats Open
Background Methods for the non-invasive quantification of changes in bladder wall thickness as potential predictors of radiation cystitis in pre-clinical research would be desirable. The use of ultrasound for this aim seems promising, but …
View article: A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats
A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats Open
Background. Methods for the non-invasive quantification of changes in bladder wall thickness as potential predictors of radiation cystitis in pre-clinical research would be desirable. The use of ultrasound for this aim seems promising, but…
View article: Predictors of 2-Year Incidence of Patient-Reported Urinary Incontinence After Post-prostatectomy Radiotherapy: Evidence of Dose and Fractionation Effects
Predictors of 2-Year Incidence of Patient-Reported Urinary Incontinence After Post-prostatectomy Radiotherapy: Evidence of Dose and Fractionation Effects Open
Objective: To investigate predictors of patient-reported urinary incontinence (PRUI) in the first 2 years after post-prostatectomy radiotherapy (PORT) with particular emphasis on possible dose-effect relationships. Patients and Methods: Tw…
View article: A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats
A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats Open
Background. Methods for the non-invasive quantification of changes in bladder wall thickness (BWT) as potential predictors of radiation cystitis (RC) in pre-clinical research would be desirable. The use of ultrasound (US) for this aim seem…