Liliana Andrade Chebli
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View article: Reply to the letter on “Brazilian guidelines for the management of tuberculosis infection in immune-mediated inflammatory diseases: is retesting in latent tuberculosis screening appropriate and safe?”
Reply to the letter on “Brazilian guidelines for the management of tuberculosis infection in immune-mediated inflammatory diseases: is retesting in latent tuberculosis screening appropriate and safe?” Open
In response to a letter addressing the Brazilian guidelines for tuberculosis infection (TBI) screening in immune-mediated inflammatory diseases (IMID), we clarify that the recommendations reflect a structured, evidence-based consensus deve…
View article: Clinical effectiveness and safety of vedolizumab versus infliximab in biologic-naïve patients with ulcerative colitis: A comparative real-world multicentric observational study
Clinical effectiveness and safety of vedolizumab versus infliximab in biologic-naïve patients with ulcerative colitis: A comparative real-world multicentric observational study Open
View article: Correction: Brazilian recommendations for the management of tuberculosis infection in immune-mediated inflammatory diseases
Correction: Brazilian recommendations for the management of tuberculosis infection in immune-mediated inflammatory diseases Open
View article: Brazilian recommendations for the management of tuberculosis infection in immune-mediated inflammatory diseases
Brazilian recommendations for the management of tuberculosis infection in immune-mediated inflammatory diseases Open
Background The risk of tuberculosis infection (TBI) and its progression to tuberculosis disease (TBD) among persons with immune-mediated inflammatory diseases (IMID) results from a complex interplay of patient and disease characteristics, …
View article: Tofacitinib for ulcerative colitis in Brazil: a multicenter observational study on effectiveness and safety
Tofacitinib for ulcerative colitis in Brazil: a multicenter observational study on effectiveness and safety Open
In this large, long-term real-world study involving patients with predominantly biologically refractory UC, tofacitinib effectively induced clinical remission and endoscopic improvement and prevented colectomy for more than 30 months, with…
View article: Clinical effectiveness and safety of vedolizumab versus infliximab in biologic-naïve patients with ulcerative colitis: A comparative real-world multicentric observational study
Clinical effectiveness and safety of vedolizumab versus infliximab in biologic-naïve patients with ulcerative colitis: A comparative real-world multicentric observational study Open
Both VDZ and IFX are effective in biologic-naïve UC patients, however VDZ demonstrated superior endoscopic outcomes, higher treatment persistence, and a better safety profile, supporting its use as a first-line therapy.
View article: Effectiveness and Safety of Ustekinumab for Ulcerative Colitis: A Brazilian Multicentric Observational Study
Effectiveness and Safety of Ustekinumab for Ulcerative Colitis: A Brazilian Multicentric Observational Study Open
Background Real-world data on the effectiveness and safety of ustekinumab (UST) in ulcerative colitis (UC) are lacking in Latin America. In this study, we aimed to describe the effectiveness and safety of UST in a real-world multicenter co…
View article: Combined clinical and radiological remission of rectovaginal fistulas using fractional CO2 vaginal laser: a case series and medium-term follow-up
Combined clinical and radiological remission of rectovaginal fistulas using fractional CO2 vaginal laser: a case series and medium-term follow-up Open
View article: DOENÇA DE CROHN METASTÁTICA PARA AS REGIÕES PENIANA E INGUINAL: RELATO DE CASO
DOENÇA DE CROHN METASTÁTICA PARA AS REGIÕES PENIANA E INGUINAL: RELATO DE CASO Open
Relato do Caso Relatamos o caso de um paciente do sexo masculino, de 58 anos, com comorbidades de hipertensão arterial sistêmica, diabetes mellitus tipo 2 e psoríase em placas. Havia 16 anos, apresentava lesões ulceradas nas regiões perian…
View article: FEBRE DE ORIGEM OBSCURA ASSOCIADA À COLESTASE DURANTE TERAPIA ANTI-TNF EM PACIENTE COM DOENÇA DE CROHN REVELANDO UMA AFECÇÃO SURPREENDENTE
FEBRE DE ORIGEM OBSCURA ASSOCIADA À COLESTASE DURANTE TERAPIA ANTI-TNF EM PACIENTE COM DOENÇA DE CROHN REVELANDO UMA AFECÇÃO SURPREENDENTE Open
Apresentação do Caso Uma mulher de 35 anos, com doença de Crohn (DC) ileal e fístula perianal, em uso de azatioprina e infliximabe (anti-TNF), em remissão da doença havia 8 meses, apresentou emagrecimento, febre, sudorese noturna e colesta…
View article: Vedolizumab in Mild-to-Moderate Crohn’s Disease Patients Naïve to Biological Therapy: A Multicentric Observational Study
Vedolizumab in Mild-to-Moderate Crohn’s Disease Patients Naïve to Biological Therapy: A Multicentric Observational Study Open
Background In real-world experience, the number of patients using vedolizumab as first-line biological therapy was low. We aimed to evaluate the effectiveness and safety of vedolizumab in mild-to-moderate Crohn’s disease (CD) biologic-naïv…
View article: Efficacy of Early Optimization of Infliximab Guided by Therapeutic Drug Monitoring during Induction—A Prospective Trial
Efficacy of Early Optimization of Infliximab Guided by Therapeutic Drug Monitoring during Induction—A Prospective Trial Open
Therapeutic drug monitoring (TDM) during induction therapy with anti-tumor necrosis factor drugs has emerged as a strategy to optimize response to these biologics and avoid undesired outcomes related to inadequate drug exposure. This study…
View article: Leukocytoclastic Vasculitis Secondary to Anti-Tumor Necrosis Factor Therapy in Inflammatory Bowel Diseases: A Multicenter Retrospective Cohort Study
Leukocytoclastic Vasculitis Secondary to Anti-Tumor Necrosis Factor Therapy in Inflammatory Bowel Diseases: A Multicenter Retrospective Cohort Study Open
Background: Vasculitis is an uncommon complication of biologics used to treat inflammatory bowel disease (IBD). This study describes a case series of vasculitis induced by anti-tumor necrosis factor (TNF) therapy in IBD patients. Methods: …
View article: P811 Combination biological or small molecule therapy in patients with refractory inflammatory bowel disease: a multicenter Brazilian experience
P811 Combination biological or small molecule therapy in patients with refractory inflammatory bowel disease: a multicenter Brazilian experience Open
Background This preliminary study describes the Brazilian experience on dual biologic therapy or small molecule combined with a biologic therapy in patients with inflammatory bowel disease (IBD) refractory to multiple biologics. Methods We…
View article: Long-term effectiveness and safety of ustekinumab in bio-naïve and bio-experienced anti-tumor necrosis factor patients with Crohn’s disease: a real-world multicenter Brazilian study
Long-term effectiveness and safety of ustekinumab in bio-naïve and bio-experienced anti-tumor necrosis factor patients with Crohn’s disease: a real-world multicenter Brazilian study Open
Background The effectiveness of ustekinumab (UST) in the treatment of Crohn’s disease (CD) has been demonstrated in the pivotal Phase 3 UNITI 1 and 2 and IM-UNITI studies in both anti-TNF-naïve and anti-TNF-exposed patients. Given the sele…
View article: Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey
Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey Open
This study indicates a distinct geographical distribution of IBD patients at highest risk for COVID-19 complications in different states of the country, which may reflect contrasting socioeconomic, educational and healthcare aspects. No as…
View article: A Rare Presentation of a Solid Pseudopapillary Neoplasm of the Pancreas
A Rare Presentation of a Solid Pseudopapillary Neoplasm of the Pancreas Open
Solid pseudopapillary neoplasms (SPN) are rare and represent a minority of all pancreatic cystic tumors. Symptoms, if present, are generally nonspecific and upper gastrointestinal bleeding is extremely uncommon as an initial presentation. …
View article: How to manage inflammatory bowel disease during the COVID-19 pandemic: A guide for the practicing clinician
How to manage inflammatory bowel disease during the COVID-19 pandemic: A guide for the practicing clinician Open
Managing inflammatory bowel disease (IBD) during the coronavirus disease 2019 (COVID-19) pandemic has been a challenge faced by clinicians and their patients, especially concerning whether to proceed with biologics and immunosuppressive ag…
View article: BRAZILIAN IBD STUDY GROUP POSITION STATEMENT ON SARS-COV2 VACCINATION
BRAZILIAN IBD STUDY GROUP POSITION STATEMENT ON SARS-COV2 VACCINATION Open
Mass vaccination offers the best strategy to fight against COVID-19 pandemic, and SARS-CoV2 vaccines are being approved in several countries for emergency use. In Brazil, vaccine approval is expected in the next few days, however potential…
View article: Brazilian ibd study group position statement on sars-cov2 vaccination/ Grupo de Estudos da Doença Inflamatória Intestinal do Brasil sobre a vacinação para SARS-CoV2
Brazilian ibd study group position statement on sars-cov2 vaccination/ Grupo de Estudos da Doença Inflamatória Intestinal do Brasil sobre a vacinação para SARS-CoV2 Open
Mass vaccination offers the best strategy to fight against COVID-19 pandemic, and SARS-CoV2 vaccines are being approved in several countries for emergency use. In Brazil, vaccine approval is expected in the next few days, however potential…
View article: Infliximab-induced remission improves physical activity in patients with active Crohn's disease
Infliximab-induced remission improves physical activity in patients with active Crohn's disease Open
SUMMARY AIM: To compare the level of physical activity (PA), exercise capacity, and body composition before and after infliximab-induced clinical remission in patients with Crohn's disease (CD). METHODS: This prospective longitudinal study…
View article: Influence of Religiousness and Spirituality on Remission Rate, Mental Health, and Quality of Life of Patients With Active Crohn’s Disease: A Longitudinal 2-Year Follow-up Study
Influence of Religiousness and Spirituality on Remission Rate, Mental Health, and Quality of Life of Patients With Active Crohn’s Disease: A Longitudinal 2-Year Follow-up Study Open
Background and Aims Studies on inflammatory bowel disease [IBD] have shown that religiousness and spirituality [R/S] were associated with better mental health and quality of life [QOL]. However, longitudinal studies assessing the impact of…
View article: Avaliação do perfil de citocinas inflamatórias e da atividade física em pacientes com doença de crohn tratados com infliximabe
Avaliação do perfil de citocinas inflamatórias e da atividade física em pacientes com doença de crohn tratados com infliximabe Open
View article: Brazilian recommendations on the safety and effectiveness of the yellow fever vaccination in patients with chronic immune-mediated inflammatory diseases
Brazilian recommendations on the safety and effectiveness of the yellow fever vaccination in patients with chronic immune-mediated inflammatory diseases Open
View article: P460 Efficacy of ustekinumab in patients with anti-TNF refractory Crohn’s disease: data from a real-world study in Brazil
P460 Efficacy of ustekinumab in patients with anti-TNF refractory Crohn’s disease: data from a real-world study in Brazil Open
Ustekinumab (UST) is a fully human monoclonal antibody against IL-12/23. UST induced a clinical response and maintained a higher rate of response than placebo in patients with Crohn's disease (CD). UST was approved in Brazil in November 20…
View article: Preparing Patients With Inflammatory Bowel Diseases ForBiological Therapies In Clinical Practice
Preparing Patients With Inflammatory Bowel Diseases ForBiological Therapies In Clinical Practice Open
Biological therapy has revolutionized the treatment of inflammatory bowel disease (IBD). Although greatly effective, theses biologics put the patients at increased risk for developing infusions and paradoxical reactions, infections and som…
View article: Colite isquêmica
Colite isquêmica Open
View article: IMPACTO DA SUPERINFECÇÃO POR CLOSTRIDIUM DIFFICILE DURANTE RECORRÊNCIAS DE COLITE ULCERATIVA OU COLITE DE CROHN NO AMBIENTE AMBULATORIAL
IMPACTO DA SUPERINFECÇÃO POR CLOSTRIDIUM DIFFICILE DURANTE RECORRÊNCIAS DE COLITE ULCERATIVA OU COLITE DE CROHN NO AMBIENTE AMBULATORIAL Open
View article: Impact of biological therapy on body composition of patients with Chron's disease
Impact of biological therapy on body composition of patients with Chron's disease Open
Summary Introduction: Protein-energy malnutrition in Crohn's disease (CD) has been reported in 20 to 92% of patients, and is associated with increased morbidity and mortality and higher costs for the health system. Anti-TNF drugs are a lan…
View article: Severe hypoproteinemia as a harbinger of Ménétrier's disease in autoimmune pancreatitis
Severe hypoproteinemia as a harbinger of Ménétrier's disease in autoimmune pancreatitis Open
Summary Ménétrier's disease is an extremely rare disease of unknown etiology causing gastric mucosal hypertrophy and protein-losing gastropathy. Rare cases of this condition have been reported in patients with autoimmune diseases. However,…