Elizabeth A. Tolley
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View article: Comparative Effectiveness of Diabetes Self-Care Interventions in African-American Adults: A Three-Arm Randomized Controlled Trial
Comparative Effectiveness of Diabetes Self-Care Interventions in African-American Adults: A Three-Arm Randomized Controlled Trial Open
Background Although studies have demonstrated that many patient-centered behavioral interventions are effective in improving diabetes self-care, little is known regarding their comparative effectiveness. Objective The Management of Diabete…
View article: Epidemiology of carbapenem-resistant Enterobacterales infections in Tennessee, 2016–2022
Epidemiology of carbapenem-resistant Enterobacterales infections in Tennessee, 2016–2022 Open
This surveillance report describes the epidemiology and clinical outcomes of carbapenem-resistant Enterobacterales (CRE) infections in Tennessee from 2016 to 2022, analysing 570 cases and 406 isolates. The incidence of CRE infections per 1…
View article: Evaluation of a Novel Battery-Operated Tumbler Device for Use in the Detection of Mouse Pathogens for Rodent Health Monitoring
Evaluation of a Novel Battery-Operated Tumbler Device for Use in the Detection of Mouse Pathogens for Rodent Health Monitoring Open
The search for alternatives to live animal sentinels in rodent health monitoring programs is fundamental to the 3Rs (Reduction, Replacement, and Refinement) of animal research. We evaluated the efficacy of a novel battery-operated tumbler …
View article: Haptoglobin genotype is a risk factor for coronary artery disease in prediabetes: A case-control study
Haptoglobin genotype is a risk factor for coronary artery disease in prediabetes: A case-control study Open
Haptoglobin 2-2 genotype had approximately four times higher odds of having CAD compared to the haptoglobin 1-1 genotype. Cases had more desirable clinical profiles, likely attributable to more aggressive treatment of traditional risk fact…
View article: Oral Health and Behavior Patterns of Women with Eating Disorders—A Clinical Pilot Study
Oral Health and Behavior Patterns of Women with Eating Disorders—A Clinical Pilot Study Open
Background: Chronic stomach regurgitation associated with eating disorders (EDs) poses a high risk for tooth erosion. This study investigated oral health conditions, behavioral patterns, and tooth erosion in women with EDs. Methods: 16 ED …
View article: Opinion: Common Errors, Omissions, and Presentation Problems in the Conduct and Reporting of Animal-based Research
Opinion: Common Errors, Omissions, and Presentation Problems in the Conduct and Reporting of Animal-based Research Open
As experienced authors, statisticians, editors, and scientists, we present the following comments to highlight some usages or omissions that are common in research manuscripts. Consideration of these comments will improve practices of data…
View article: Characterization of the Metabolome of Breast Tissues from Non-Hispanic Black and Non-Hispanic White Women Reveals Correlations between Microbial Dysbiosis and Enhanced Lipid Metabolism Pathways in Triple-Negative Breast Tumors
Characterization of the Metabolome of Breast Tissues from Non-Hispanic Black and Non-Hispanic White Women Reveals Correlations between Microbial Dysbiosis and Enhanced Lipid Metabolism Pathways in Triple-Negative Breast Tumors Open
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer that is non-responsive to hormonal therapies and disproportionately impact women of African ancestry. We previously showed that TN breast tumors have a distinct mi…
View article: Feasibility of a Brief Intervention to Increase Rapid Primary Care Follow-Up Among African American Patients With Uncontrolled Diabetes
Feasibility of a Brief Intervention to Increase Rapid Primary Care Follow-Up Among African American Patients With Uncontrolled Diabetes Open
The management of diabetes, like many other chronic conditions, depends on effective primary care engagement. Patients with diabetes without a usual source of care have a higher risk of uncontrolled disease, hospitalizations, and early dea…
View article: Conditional loss of <i>Engrailed1/2</i> in <i>Atoh1</i>‐derived excitatory cerebellar nuclear neurons impairs eupneic respiration in mice
Conditional loss of <i>Engrailed1/2</i> in <i>Atoh1</i>‐derived excitatory cerebellar nuclear neurons impairs eupneic respiration in mice Open
Evidence for a cerebellar role during cardiopulmonary challenges has long been established, but studies of cerebellar involvement in eupneic breathing have been inconclusive. Here we investigated temporal aspects of eupneic respiration in …
View article: Relationship Between Standardized Test Scores and Board Certification Exams in a Combined Internal Medicine/Pediatrics Residency Program
Relationship Between Standardized Test Scores and Board Certification Exams in a Combined Internal Medicine/Pediatrics Residency Program Open
Background Combined Internal Medicine/Pediatrics (Med/Peds) residencies rely on categorical program data to predict pass rates for the American Board of Internal Medicine Certifying Exam (ABIM-CE) and the American Board of Pediatrics Certi…
View article: Beta-adrenergic blockade for attenuation of catecholamine surge after traumatic brain injury: a randomized pilot trial
Beta-adrenergic blockade for attenuation of catecholamine surge after traumatic brain injury: a randomized pilot trial Open
Background Beta-blockers have been proven in multiple studies to be beneficial in patients with traumatic brain injury. Few prospective studies have verified this and no randomized controlled trials. Additionally, most studies do not titra…
View article: Sit4 and PP2A Dephosphorylate Nitrogen Catabolite Repression-Sensitive Gln3 When TorC1 Is Up- as Well as Downregulated
Sit4 and PP2A Dephosphorylate Nitrogen Catabolite Repression-Sensitive Gln3 When TorC1 Is Up- as Well as Downregulated Open
Saccharomyces cerevisiae lives in boom and bust nutritional environments. Sophisticated regulatory systems have evolved to rapidly cope with these changes while preserving intracellular homeostasis. Target of Rapamycin Complex 1 (TorC1), i…
View article: Modulation of endoplasmic reticulum stress and the unfolded protein response in cancerous and noncancerous cells
Modulation of endoplasmic reticulum stress and the unfolded protein response in cancerous and noncancerous cells Open
Objectives: The bio-field array is a device that generates a dielectrophoretic electromagnetic field when placed in a hypotonic saline solution and a direct current of approximately 3 A is applied. It is known that cell physiology is guide…
View article: Underutilization of Aldosterone Antagonists in Heart Failure
Underutilization of Aldosterone Antagonists in Heart Failure Open
Background: Treatment with an aldosterone antagonist (AA) has been shown in multiple trials to reduce heart failure (HF)–related morbidity, mortality, and hospital readmission. American College of Cardiology Foundation (ACCF) and American …
View article: Cardiovascular mortality among liver transplant recipients with nonalcoholic steatohepatitis in the United States-a retrospective study
Cardiovascular mortality among liver transplant recipients with nonalcoholic steatohepatitis in the United States-a retrospective study Open
Nonalcoholic steatohepatitis (NASH) has become an increasingly important indication for liver transplantation (LT), and there has been a particular concern of excessive cardiovascular-related mortality in this group. Using the United Netwo…
View article: Characterization of Body Composition and Fat Mass Distribution 1 Year After Kidney Transplantation
Characterization of Body Composition and Fat Mass Distribution 1 Year After Kidney Transplantation Open
Purpose: In some recipients, significant weight gain occurs after kidney transplantation. Weight gain is associated with poor outcomes, particularly increased cardiovascular risk. In this study, we characterized changes in body mass index …
View article: Medication therapy management and adherence among US renal transplant recipients
Medication therapy management and adherence among US renal transplant recipients Open
The findings provide evidence that access to MTM services increases IST adherence among RTRs.