Andreas Erhardt
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View article: Frequency, Severity and Impact of Pegylated Interferon Alpha–Associated Flares in Hepatitis D Infection
Frequency, Severity and Impact of Pegylated Interferon Alpha–Associated Flares in Hepatitis D Infection Open
We analysed the frequency, severity and impact of hepatitis flares in a large Phase 2 study investigating pegylated interferon‐alfa‐2a (PEG‐IFNa) for the treatment of hepatitis D. In the HIDIT‐II study, 120 patients were treated for 96 wee…
View article: Towards a genomic resolution of the Phengaris alcon species complex
Towards a genomic resolution of the Phengaris alcon species complex Open
Taxonomic entities below the species level often pose difficulties for conservation practice, especially when they are ecologically distinct from the nominal species. Genomic tools provide the opportunity to study and potentially resolve s…
View article: Towards a genomic resolution of the Phengaris alcon species complex
Towards a genomic resolution of the Phengaris alcon species complex Open
Taxonomic entities below the species level often pose difficulties for conservation practice, especially when they are ecologically distinct from the nominal species. Genomic tools provide the opportunity to study and potentially resolve s…
View article: Five‐year follow‐up of 96 weeks peginterferon plus tenofovir disoproxil fumarate in hepatitis D
Five‐year follow‐up of 96 weeks peginterferon plus tenofovir disoproxil fumarate in hepatitis D Open
Background & Aims Until recently, pegylated interferon‐alfa‐2a (PEG‐IFNa) therapy was the only treatment option for patients infected with hepatitis D virus (HDV). Treatment with PEG‐IFNa with or without tenofovir disoproxil fumarate (TDF)…
View article: Quality‐of‐life scores improve after 96 weeks of <scp>PEG‐IFNa</scp>‐2a treatment of hepatitis D: An analysis of the <scp>HIDIT‐II</scp> trial
Quality‐of‐life scores improve after 96 weeks of <span>PEG‐IFNa</span>‐2a treatment of hepatitis D: An analysis of the <span>HIDIT‐II</span> trial Open
Background & Aims Infection with the hepatitis D virus (HDV) causes the most severe form of viral hepatitis with a high risk to develop clinical complications of liver disease. In addition, hepatitis delta has been shown to be associated w…
View article: Comment on Depoorter, L.; Vandenplas, Y. Probiotics in Pediatrics. A Review and Practical Guide. Nutrients 2021, 13, 2176
Comment on Depoorter, L.; Vandenplas, Y. Probiotics in Pediatrics. A Review and Practical Guide. Nutrients 2021, 13, 2176 Open
We read the review by Depoorter et al. [...]
View article: Using ecological and field survey data to establish a national list of the wild bee pollinators of crops
Using ecological and field survey data to establish a national list of the wild bee pollinators of crops Open
View article: Clinical effectiveness of bidirectional fecal microbiota transfer in the treatment of recurrent Clostridioides difficile infections
Clinical effectiveness of bidirectional fecal microbiota transfer in the treatment of recurrent Clostridioides difficile infections Open
In our analysis, bFMT on the same day significantly increased primary cure rate at D30 and D90. These data require prospective confirmation but suggest that route of application may play a significant role in optimizing patient outcomes. C…
View article: Residual low HDV viraemia is associated HDV RNA relapse after PEG‐IFNa‐based antiviral treatment of hepatitis delta: Results from the HIDIT‐II study
Residual low HDV viraemia is associated HDV RNA relapse after PEG‐IFNa‐based antiviral treatment of hepatitis delta: Results from the HIDIT‐II study Open
The role of low levels of HDV‐RNA during and after interferon therapy of hepatitis D is unknown. We re‐analysed HDV RNA in 372 samples collected in the HIDIT‐2 trial (Wedemeyer et al, Lancet Infectious Diseases 2019) with the Robogene assa…
View article: Residual low HDV viremia is associated with HDV RNA relapse after PEG-IFNa-based antiviral treatment of hepatitis D (delta): results from the HIDIT-II study
Residual low HDV viremia is associated with HDV RNA relapse after PEG-IFNa-based antiviral treatment of hepatitis D (delta): results from the HIDIT-II study Open
View article: The impact of technical and clinical factors on fecal microbiota transfer outcomes for the treatment of recurrent <i>Clostridioides difficile</i> infections in Germany
The impact of technical and clinical factors on fecal microbiota transfer outcomes for the treatment of recurrent <i>Clostridioides difficile</i> infections in Germany Open
Introduction Fecal microbiota transfer (FMT) is highly effective in the treatment and prevention of recurrent Clostridioides difficile infection (rCDI) with cure rates of about 80% after a single treatment. Nevertheless, the reasons for fa…
View article: Tag- und Nachtfalter in alpinen Lebensraumen
Tag- und Nachtfalter in alpinen Lebensraumen Open
Schmetterlinge bilden mit über 150 000 Arten eine der grössten Insektenordnungen der Welt. In der Schweiz kommen rund 3700 Arten vor, davon sind 182 Arten echte Tagfalter. Wir konnten auf der Furka in kurzer Zeit 27 Tagfalterarten (15%) un…
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Frontmatter Open
View article: A Long-Lasting Dysphagia
A Long-Lasting Dysphagia Open
View article: Transient Elastography for the Detection of Liver Damage in Patients with HIV
Transient Elastography for the Detection of Liver Damage in Patients with HIV Open
View article: Transient elastography improves detection of liver cirrhosis compared to routine screening tests
Transient elastography improves detection of liver cirrhosis compared to routine screening tests Open
Transient elastography is superior to routine diagnostic tests allowing detection of liver cirrhosis in additional 10%-16% of patients with chronic liver disease that would have been missed by clinical examinations.