Ana M. Giménez‐Arnau
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View article: Anogenital Contact Dermatitis in Spain: A <scp>REIDAC</scp> Study of Patients Undergoing Patch Testing in 2019–2024
Anogenital Contact Dermatitis in Spain: A <span>REIDAC</span> Study of Patients Undergoing Patch Testing in 2019–2024 Open
Background The REIDAC (Spanish Registry for Research in Contact Dermatitis) conducts nationwide epidemiological surveillance of contact dermatitis in Spain. Anogenital involvement within REIDAC has not been previously studied. Objectives T…
View article: Current treatment practices and efficacy in solar urticaria: insights from a patient survey
Current treatment practices and efficacy in solar urticaria: insights from a patient survey Open
Background Solar urticaria (SolU) is a rare chronic inducible urticaria and photodermatosis, presenting with wheal/flare formation accompanied by severe itch, following exposure to light in the triggering action spectrum. Therapeutic optio…
View article: Characterization of Contact Urticaria Syndrome Phenotypes: A Retrospective Study of 95 Cases
Characterization of Contact Urticaria Syndrome Phenotypes: A Retrospective Study of 95 Cases Open
Contact urticaria syndrome, encompassing immunological contact urticaria and protein contact dermatitis, comprises immediate cutaneous reactions with potential systemic manifestations, including anaphylaxis. These conditions are frequently…
View article: Remibrutinib in chronic spontaneous urticaria: 52-week results from two phase 3 studies
Remibrutinib in chronic spontaneous urticaria: 52-week results from two phase 3 studies Open
Remibrutinib showed sustained efficacy and a consistent, favorable long-term safety profile in patients with CSU remaining symptomatic despite second-generation H1-antihistamines.
View article: Physician-Reported Treatment Patterns in Moderate to Severe Chronic Hand Eczema: the RWEAL Multinational Medical Chart Review
Physician-Reported Treatment Patterns in Moderate to Severe Chronic Hand Eczema: the RWEAL Multinational Medical Chart Review Open
Despite being a first-line treatment, 40% of patients with CHE were inadequately treated with or contraindicated to TCS. Over one-quarter of patients progressed to phototherapy or systemic therapy. These results suggest a lack of effective…
View article: Contact Allergy in Children in Europe: A Proposal for a Paediatric European Baseline Series
Contact Allergy in Children in Europe: A Proposal for a Paediatric European Baseline Series Open
Background Contact allergy is common in children, but no paediatric baseline series ( pEBS ) exists in Europe, despite recommendations in several countries. Objectives To collect and compare patch testing data from European centres to prop…
View article: Sex matters in <scp>CSU</scp> : Women face greater burden and poorer urticaria control, especially in midlife— <scp>CURE</scp> insights
Sex matters in <span>CSU</span> : Women face greater burden and poorer urticaria control, especially in midlife— <span>CURE</span> insights Open
Background Chronic spontaneous urticaria (CSU), a disease predominantly affecting females, has limited information available on its differences between females and males of varying ages. Objectives To investigate sex differences in age gro…
View article: The Prevalence of Symptomatic Dermographism: Results of the International <scp>UCARE PREVALENCE</scp>‐D Study
The Prevalence of Symptomatic Dermographism: Results of the International <span>UCARE PREVALENCE</span>‐D Study Open
Background The prevalence of symptomatic dermographism ( SD ) in the general population remains unclear. This study aimed to internationally estimate the prevalence of SD and two other dermographic subtypes—physiological red dermographism …
View article: Transcriptomic Analysis of Allergic Patch Test Reactions in Non‐Atopic Patients: A Comparative Study Across Multiple Allergens
Transcriptomic Analysis of Allergic Patch Test Reactions in Non‐Atopic Patients: A Comparative Study Across Multiple Allergens Open
Background Immune mechanisms underlying elicitation in allergic contact dermatitis (ACD) have yet to be fully elucidated. Previous studies have shown a double‐faceted nature of ACD with both common biomarkers among different allergens and …
View article: Exploring the impact of chronic urticaria profile as a key predictor of alexithymia: A cross‐sectional study
Exploring the impact of chronic urticaria profile as a key predictor of alexithymia: A cross‐sectional study Open
Introduction The relationship between chronic urticaria (CU) and alexithymia, a cognitive‐affective impairment characterized by difficulty in identifying and expressing emotions, is complex and underexplored. This study aimed to identify p…
View article: P072 Improvement across work productivity and quality of life with remibrutinib treatment in patients with chronic spontaneous urticaria in the REMIX-1/2 trials
P072 Improvement across work productivity and quality of life with remibrutinib treatment in patients with chronic spontaneous urticaria in the REMIX-1/2 trials Open
Remibrutinib, an oral, highly selective Bruton tyrosine kinase inhibitor, has shown efficacy and favourable safety in the REMIX-1/2 studies in patients with chronic spontaneous urticaria (CSU). Herein, we report the impact of remibrutinib …
View article: Variability in Paediatric Patch Test Practices Across Europe: A Survey From the European Baseline Series (<scp>EBS</scp>) Working Party on Behalf of the European Society of Contact Dermatitis (<scp>ESCD</scp>)
Variability in Paediatric Patch Test Practices Across Europe: A Survey From the European Baseline Series (<span>EBS</span>) Working Party on Behalf of the European Society of Contact Dermatitis (<span>ESCD</span>) Open
Background Allergic contact dermatitis (ACD) is an increasingly recognised condition in children and adolescents. However, there is limited knowledge about the different paediatric patch test procedures in European patch test clinics. Obje…
View article: Long‐Term Real‐World Effectiveness of Rupatadine in Chronic Urticaria: A Retrospective Observational Study
Long‐Term Real‐World Effectiveness of Rupatadine in Chronic Urticaria: A Retrospective Observational Study Open
Background Chronic urticaria (CU) impacts health‐related quality of life, particularly when chronic spontaneous urticaria (CSU) is associated with angioedema and/or chronic inducible urticaria (CIndU). The efficacy of second‐generation ant…
View article: International survey of treatment practices for atopic dermatitis in pregnant and breastfeeding women: Physician perspectives
International survey of treatment practices for atopic dermatitis in pregnant and breastfeeding women: Physician perspectives Open
Summary Background and Objectives Systemic treatment of pregnant/breastfeeding atopic dermatitis (AD) patients is challenging due to limited safety data. We explored treatment practices with systemic agents, including the guideline‐recomme…
View article: Spectrum and Impact of Reported Side Effects of Omalizumab in Patients With Chronic Urticaria: A Long‐Term Multicentre Real‐World Study
Spectrum and Impact of Reported Side Effects of Omalizumab in Patients With Chronic Urticaria: A Long‐Term Multicentre Real‐World Study Open
Background Chronic urticaria (CU) treatment with omalizumab is considered safe in short‐term studies. Large real‐world studies focusing on the long‐term safety of omalizumab and associated factors are lacking. We aimed to investigate the s…
View article: Consensus on core domains for hand eczema trials: Signs, symptoms, control and quality of life
Consensus on core domains for hand eczema trials: Signs, symptoms, control and quality of life Open
Background Hand eczema (HE) is a common and complex skin disease. A uniform set of core outcomes and related measures for use in clinical trials is lacking, making it difficult to compare results across HE studies. Objective To reach conse…
View article: Rilzabrutinib in Antihistamine-Refractory Chronic Spontaneous Urticaria
Rilzabrutinib in Antihistamine-Refractory Chronic Spontaneous Urticaria Open
Importance Chronic spontaneous urticaria (CSU) is a skin disease driven mainly by the activation of cutaneous mast cells through various mechanisms. Bruton tyrosine kinase (BTK), expressed in B cells and mast cells, plays a critical role i…
View article: Contact Urticaria and Related Conditions: Clinical Review
Contact Urticaria and Related Conditions: Clinical Review Open
Contact urticaria (CoU) is an immediate contact reaction occurring within minutes to an hour after exposure to specific proteins or chemicals. CoU is categorised into non‐immunologic (NI‐CoU) and immunologic (I‐CoU) types, with I‐CoU poten…
View article: Redefining Omalizumab Discontinuation in Chronic Spontaneous Urticaria: The Value of Optimization and Predictive Factors of Relapse. A 52-Week Multicenter Study
Redefining Omalizumab Discontinuation in Chronic Spontaneous Urticaria: The Value of Optimization and Predictive Factors of Relapse. A 52-Week Multicenter Study Open
Optimization seems to reduce the relapse rate after discontinuation. The most relevant factors for recurrence are associated with the duration of treatment at different doses of omalizumab, along with the baseline CRP and total IgE levels.…
View article: A Review of Hand Eczema Subtypes: Clinical Features, Biomarkers and Treatment Strategies
A Review of Hand Eczema Subtypes: Clinical Features, Biomarkers and Treatment Strategies Open
Hand eczema is a common dermatological condition that significantly impairs quality of life. The classification of hand eczema has been considered an essential step for its management. The diagnosis of hand eczema relies on the aetiologica…
View article: Gut microbial alteration in chronic spontaneous urticaria unresponsive to second generation antihistamines and its correlation with disease characteristics‐ a cross‐sectional case‐control study
Gut microbial alteration in chronic spontaneous urticaria unresponsive to second generation antihistamines and its correlation with disease characteristics‐ a cross‐sectional case‐control study Open
Background Gut microbial involvement has been speculated in chronic spontaneous urticaria (CSU). The aim of the study was to compare the gut microbiome composition and diversity in CSU patients uncontrolled with second‐generation antihista…
View article: Advances in Atopic Dermatitis and Chronic Hand Eczema: Delgocitinib and Tralokinumab
Advances in Atopic Dermatitis and Chronic Hand Eczema: Delgocitinib and Tralokinumab Open
This article summarizes selected poster presentations from the 2024 Fall Clinical Dermatology Conference (FCDC), with a focus on updated data for tralokinumab in atopic dermatitis (AD) and delgocitinib cream in chronic hand eczema (CHE), a…
View article: Patch test results to the Spanish baseline patch test series according to age groups: A multicentric prospective study from 2019 to 2023
Patch test results to the Spanish baseline patch test series according to age groups: A multicentric prospective study from 2019 to 2023 Open
Introduction Patch test results may be influenced by age‐related factors. However, there is still discordant evidence between age and patch test results. Objectives We aim to evaluate the patch test results reflecting skin sensitisation, t…
View article: Omalizumab is effective and safe in chronic inducible urticaria (CIndU): Real‐world data from a large multi‐national UCARE study
Omalizumab is effective and safe in chronic inducible urticaria (CIndU): Real‐world data from a large multi‐national UCARE study Open
Background Long‐term data on the effectiveness and safety of omalizumab for chronic inducible urticaria (CIndU) in large populations are lacking. Objective To evaluate the effectiveness, safety, estimated omalizumab treatment duration and …
View article: An emerging epidemic of allergic contact dermatitis due to phytonadione epoxide (oxidised vitamin K1)
An emerging epidemic of allergic contact dermatitis due to phytonadione epoxide (oxidised vitamin K1) Open
Background Reports of allergic contact dermatitis (ACD) to phytonadione epoxide (PE) in cosmetics suggest that PE is as powerful a sensitiser as its parent compound phytonadione. Objective To evaluate a case series of ACD to PE in Spain. M…
View article: Lymphopenia in Chronic Spontaneous Urticaria is Linked to Basopenia and Eosinopenia
Lymphopenia in Chronic Spontaneous Urticaria is Linked to Basopenia and Eosinopenia Open
Circulating blood numbers of lymphocytes in chronic spontaneous urticaria (CSU) have not been given sufficient attention. Histopathological analysis of wheals in CSU has demonstrated an increased number of mast cells (MCs) and a perivascul…