Gordon A. Ferns
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View article: Dietary acid load and its association with all-cause mortality, cardiovascular mortality, and events
Dietary acid load and its association with all-cause mortality, cardiovascular mortality, and events Open
This prospective cohort study examined the association between dietary acid load and cardiovascular disease (CVD) incidence, CVD mortality, and all-cause mortality in an Iranian population. A total of 6,482 adults (59.83% female) aged 35-6…
View article: Machine Learning-Based Predictive Modeling of Factors Associated with Low HDL-C Levels: Insights from a Large-Scale Cohort Study
Machine Learning-Based Predictive Modeling of Factors Associated with Low HDL-C Levels: Insights from a Large-Scale Cohort Study Open
Introduction Our study applies machine learning methods to identify determinants of low–high-density lipoprotein cholesterol (HDL-C) in northeastern Iran. Clarifying these risk factors may support earlier diagnosis and treatment of cardiov…
View article: Serum vitamin D and lipid profile differences between breastfed and Formula-fed infants
Serum vitamin D and lipid profile differences between breastfed and Formula-fed infants Open
Background The serum levels of some biochemical markers reflect an individual’s health status, particularly during infancy. This study aimed to compare the levels of serum vitamin D and lipid profile between two groups of infants: those ex…
View article: Association Between Serum Syndecan 1 Levels and Metabolic Syndrome Parameters: A Comparative Cross‐Sectional Study
Association Between Serum Syndecan 1 Levels and Metabolic Syndrome Parameters: A Comparative Cross‐Sectional Study Open
Introduction Previous studies have linked Syndecans (SDCs) to hypertension (HTN), BMI and the prevalence of coronary artery disease (CAD). The relationship between SDCs and metabolic syndrome (MetS) has not been explored. This study aimed …
View article: Resveratrol and Urological Cancers: Taking Stock of the Current Evidence
Resveratrol and Urological Cancers: Taking Stock of the Current Evidence Open
Urological cancers, such as prostate cancer (PC), bladder cancer (BC), renal cell carcinoma (RCC), and testicular cancer (TC), are major causes of morbidity and mortality. Effective therapies depend on factors such as cancer type, stage, g…
View article: Dietary intakes in relation to nutrition recommendations and dietary quality in an Iranian adult population: the results of the Food and Nutrition Surveillance (FNS)
Dietary intakes in relation to nutrition recommendations and dietary quality in an Iranian adult population: the results of the Food and Nutrition Surveillance (FNS) Open
This study indicated that carbohydrate and protein intakes were within the recommended ranges, while fat consumption was elevated in both adults and the elderly. Widespread micronutrient insufficiencies- especially in retinol, folate, vita…
View article: Association Between Socio‐Economic Status (SES) and the Traditional Risk Factors of Cardiovascular Diseases (CVD): A Cross‐Sectional MASHAD Cohort Study Results
Association Between Socio‐Economic Status (SES) and the Traditional Risk Factors of Cardiovascular Diseases (CVD): A Cross‐Sectional MASHAD Cohort Study Results Open
Background and Aims Socio‐economic status (SES) has been shown to be associated with cardiovascular disease. We aimed to investigate the relationship between SES and traditional risk factors for cardiovascular diseases in 35 to 65 adults o…
View article: A Novel Composite Index for Cardiovascular Risk: The Cholesterol, high-density lipoprotein, Glucose (CHG) Index
A Novel Composite Index for Cardiovascular Risk: The Cholesterol, high-density lipoprotein, Glucose (CHG) Index Open
Background Cardiovascular diseases (CVDs) are a leading cause of death, with traditional risk factors like dyslipidemia, insulin resistance (IR), and obesity studied extensively. However, current indices do not fully integrate glucose and …
View article: The association between dietary acid load and indices of insulin resistance
The association between dietary acid load and indices of insulin resistance Open
The role of diet-induced acid-base imbalance in insulin resistance (IR) and related cardiometabolic abnormalities has attracted considerable attention. This study sought to investigate the association between dietary acid load and IR indic…
View article: Association of restless legs syndrome and obesity: A sub-population of the MASHAD cohort study
Association of restless legs syndrome and obesity: A sub-population of the MASHAD cohort study Open
There was a significant association between BMI and RLS. A BMI>30 kg/m2 increased the odds of RLS by 1.50 times in the study population.
View article: The association between age at menarche (AAM) and cardiovascular disease (CVD) risk factors in the MASHAD cohort study
The association between age at menarche (AAM) and cardiovascular disease (CVD) risk factors in the MASHAD cohort study Open
Age at menarche may be associated with cardiovascular disease risk factors in different ethnic groups. The purpose of this study was to identify the association of cardiovascular disease (CVD) risk factors with age at menarche (AAM) in Mas…
View article: Correction: Alaei et al. Therapeutic Potential of Targeting the Cytochrome P450 Enzymes Using Lopinavir/Ritonavir in Colorectal Cancer: A Study in Monolayers, Spheroids and In Vivo Models. Cancers 2023, 15, 3939
Correction: Alaei et al. Therapeutic Potential of Targeting the Cytochrome P450 Enzymes Using Lopinavir/Ritonavir in Colorectal Cancer: A Study in Monolayers, Spheroids and In Vivo Models. Cancers 2023, 15, 3939 Open
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View article: Fibroblast growth factor receptor 1 gene (FGFR1) amplification in non-small cell lung cancer (NSCLC) by real-time PCR.
Fibroblast growth factor receptor 1 gene (FGFR1) amplification in non-small cell lung cancer (NSCLC) by real-time PCR. Open
The frequency of FGFR1 amplification is estimated at 20% in the current study (26% in SCC versus 11% in adenocarcinoma; p-value= 0.07). Moreover, we found a direct association between FGFR1 amplification and cigarette smoking. However, no …
View article: Assessing the efficacy of herbal supplements for managing obesity: A comprehensive review of global clinical trials.
Assessing the efficacy of herbal supplements for managing obesity: A comprehensive review of global clinical trials. Open
Obesity remains a significant worldwide health concern, and further research into other strategies, including herbal weight-loss medications, is necessary. By reviewing clinical trials, this study aims to evaluate the effectiveness of herb…
View article: Vanillic acid as a promising intervention for metabolic syndrome: Preclinical studies.
Vanillic acid as a promising intervention for metabolic syndrome: Preclinical studies. Open
Metabolic syndrome is a clustering of metabolic abnormalities and anthropometric factors that increase the risk of cardiovascular disease and type 2 diabetes mellitus. As the search for effective treatments intensifies, attention has turne…
View article: Prognostic value of circulating uric acid in gastrointestinal cancers, a systematic review and meta-analysis.
Prognostic value of circulating uric acid in gastrointestinal cancers, a systematic review and meta-analysis. Open
Serum uric acid level is significantly linked to survival outcomes in patients with gastrointestinal cancers. Serum uric acid levels may be an effective prognostic marker associated with clinical outcomes in patients with gastrointestinal …
View article: Food Quality Is Associated With Depression, Anxiety, and Stress Among Recovered COVID-19 Patients: Finding From a Case-Control Study
Food Quality Is Associated With Depression, Anxiety, and Stress Among Recovered COVID-19 Patients: Finding From a Case-Control Study Open
Following up with recovered coronavirus disease 2019 (COVID-19) patients is necessary. Given the importance of psychological function accompanied by significant effects of food quality, we want to examine the association between food quali…
View article: Multivariate linear regression to predict association of non‐invasive arterial stiffness with cardiovascular events
Multivariate linear regression to predict association of non‐invasive arterial stiffness with cardiovascular events Open
Background Arterial stiffness is a crucial factor in determining an increase in systolic blood pressure and pulse pressure and can also predict the development of cardiovascular disease (CVD). The purpose of this study was to examine the r…
View article: The diagnostic and prognostic value of <i>C1orf174 </i>in colorectal cancer
The diagnostic and prognostic value of <i>C1orf174 </i>in colorectal cancer Open
Introduction: Colorectal cancer (CRC) is among the lethal cancers, indicating the need for the identification of novel biomarkers for the detection of patients in earlier stages. RNA and microRNA sequencing were analyzed using bioinformati…