F. Anthony Greco
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View article: Ergogenic effects of a 10-day L-citrulline supplementation on time to exhaustion and cardiorespiratory and metabolic responses in healthy individuals: a double-blind, randomised, placebo-controlled crossover trial
Ergogenic effects of a 10-day L-citrulline supplementation on time to exhaustion and cardiorespiratory and metabolic responses in healthy individuals: a double-blind, randomised, placebo-controlled crossover trial Open
Introduction L-Citrulline supplementation has been a topic of debate due to its potential to augment L-arginine bioavailability and nitric oxide production. However, it remains uncertain whether it can truly serve as an ergogenic aid in en…
View article: Salvage therapy with allogeneic invariant natural killer cells in a heavily pre-treated germ cell tumor
Salvage therapy with allogeneic invariant natural killer cells in a heavily pre-treated germ cell tumor Open
Invariant natural killer T (iNKT) cells, previously considered to be tissue-resident, are an emerging and versatile allogeneic cell therapy with potent anti-tumor activity, acting at the interplay between innate and adaptive immune respons…
View article: Patients with Multiple Myeloma Have Increased Risks of Medical, but Not Surgical, Complications Following Total Shoulder Arthroplasty
Patients with Multiple Myeloma Have Increased Risks of Medical, but Not Surgical, Complications Following Total Shoulder Arthroplasty Open
Background: Multiple myeloma (MM) is a hematologic malignancy associated with characteristic lytic bone lesions. Due to weakened bone quality from these lesions, MM has been previously associated with poor orthopaedic surgery outcomes, but…
View article: Anesthesia for Ear, Nose and Throat Surgery: a Brief guide
Anesthesia for Ear, Nose and Throat Surgery: a Brief guide Open
In the surgery room, disagreements between surgeons and anaesthesiologists, regarding the conditions and methods of surgery are not uncommon. This is particularly true for surgeries involving head and neck, where anatomical and physiologic…
View article: Selective Vestibular Neurectomy through the Presigmoid Retrolabyrinthine Approach in the Treatment of Meniere’s Disease
Selective Vestibular Neurectomy through the Presigmoid Retrolabyrinthine Approach in the Treatment of Meniere’s Disease Open
Background: Meniere’s disease (MD) is a disabling disease, especially in patients who are refractory to medical therapy. Moreover, selective vestibular neurectomy (VN), in these selected cases, can be considered a surgical alternative whic…
View article: Endolymphatic Duct and Sac Decompression: A New Life for an Old Technique
Endolymphatic Duct and Sac Decompression: A New Life for an Old Technique Open
BACKGROUND: Ménière’s disease is an inner ear disorder causing recurrent vertigo, hearing loss, and tinnitus. Diagnosis is based on the variability of the symptoms over time and absence of radiological abnormalities. Medical therapy is eff…
View article: Supplementary Data from Development and Validation of a Novel Nomogram for Individualized Prediction of Survival in Cancer of Unknown Primary
Supplementary Data from Development and Validation of a Novel Nomogram for Individualized Prediction of Survival in Cancer of Unknown Primary Open
Supplementary Data
View article: Endolymphatic duct and sac decompression: A new technique for Ménière’s disease treatment
Endolymphatic duct and sac decompression: A new technique for Ménière’s disease treatment Open
Background: The present article aims to introduce the endolymphatic duct and sac decompression technique (DASD) and to give a spotlight on its benefits in Ménière’s disease (MD) treatment. Methods: Eighty-two patients with intractable MD w…
View article: Minimal invasive resurfacing: an innovative technique for the superior semicircular canal dehiscence. A case series
Minimal invasive resurfacing: an innovative technique for the superior semicircular canal dehiscence. A case series Open
The superior semicircular canal dehiscence is a vestibular disease recognized condition in recent years, and surgical therapy has been modeling itself over the years to ensure the control of vestibular symptoms and auditory symptoms. In th…
View article: Development and Validation of a Novel Nomogram for Individualized Prediction of Survival in Cancer of Unknown Primary
Development and Validation of a Novel Nomogram for Individualized Prediction of Survival in Cancer of Unknown Primary Open
Purpose: Prognostic uncertainty is a major challenge for cancer of unknown primary (CUP). Current models limit a meaningful patient-provider dialogue. We aimed to establish a nomogram for predicting overall survival (OS) in CUP based on ro…
View article: Erlotinib plus either pazopanib or placebo in patients with previously treated advanced non–small cell lung cancer: A randomized, placebo‐controlled phase 2 trial with correlated serum proteomic signatures
Erlotinib plus either pazopanib or placebo in patients with previously treated advanced non–small cell lung cancer: A randomized, placebo‐controlled phase 2 trial with correlated serum proteomic signatures Open
BACKGROUND This study compared the efficacy and safety of treatment with erlotinib plus pazopanib versus erlotinib plus placebo in patients with previously treated advanced non–small cell lung cancer (NSCLC). METHODS Patients with progress…
View article: Randomized phase 2 trial of pemetrexed, pemetrexed/bevacizumab, and pemetrexed/carboplatin/bevacizumab in patients with stage IIIB/IV non–small cell lung cancer and an Eastern Cooperative Oncology Group performance status of 2
Randomized phase 2 trial of pemetrexed, pemetrexed/bevacizumab, and pemetrexed/carboplatin/bevacizumab in patients with stage IIIB/IV non–small cell lung cancer and an Eastern Cooperative Oncology Group performance status of 2 Open
BACKGROUND The best treatment for patients with advanced non–small cell lung cancer (NSCLC) and a poor performance status is not well defined. In this phase 2 trial, patients were randomized to receive treatment with either single‐agent pe…
View article: Revisiting the Selective Vestibular Neurotomy for Intractable Ménière—s Disease in the Era of Endoscopy and Intraoperative Advanced Neuromonitoring
Revisiting the Selective Vestibular Neurotomy for Intractable Ménière—s Disease in the Era of Endoscopy and Intraoperative Advanced Neuromonitoring Open
Background Vestibular neurectomy is considered a quite effective salvage procedure to control intractable vertigo associated with Meniere's disease while preserving hearing and facial nerve function. However, it is still a potentially very…
View article: Paclitaxel/carboplatin with or without belinostat as empiric first‐line treatment for patients with carcinoma of unknown primary site: A randomized, phase 2 trial
Paclitaxel/carboplatin with or without belinostat as empiric first‐line treatment for patients with carcinoma of unknown primary site: A randomized, phase 2 trial Open
BACKGROUND The objective of this study was to evaluate the efficacy of belinostat, a histone deacetylase inhibitor, when added to paclitaxel/carboplatin in the empiric first‐line treatment of patients with carcinoma of unknown primary site…