Abstract Introduction The most dreaded complication of penile prosthesis surgery is infection, the rates of which have declined to 1-3% for high volume implanters. Historically each implanter utilized their own individualized combination of antibiotics for their dip and irrigant, however the introduction of 0.05% chlorhexidine gluconate (CHG) to the market offered the possibility of a consistent high quality antibiotic solution that had proven effectiveness against a broad range of pathogens. However, a growing bo…