Antje Haehner
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View article: Hippocampal dysfunction after autoimmune encephalitis depending on the antibody type
Hippocampal dysfunction after autoimmune encephalitis depending on the antibody type Open
Background Comprehensive neurocognitive function analyses of autoimmune encephalitis (AE) patients, especially long-term ones, are rare. This study aims to measure cognitive function in patients diagnosed with AE. Methods This case–control…
View article: Detection of odorants in odour mixtures among healthy people and patients with olfactory dysfunction
Detection of odorants in odour mixtures among healthy people and patients with olfactory dysfunction Open
Target odorant detection in mixtures has been shown to become more difficult as the number of background odorants increases and falls below chance level in mixtures with 16 components. Our aim was to investigate target odorant detection in…
View article: Can neurodegeneration be predicted based on identification of a single odor: a commentary on Diez et al. (2024)
Can neurodegeneration be predicted based on identification of a single odor: a commentary on Diez et al. (2024) Open
In their recent paper, Diez et al. demonstrate that tau pathology spreads to the primary olfactory structures from the medial temporal lobe and brainstem, and that tau accumulation might be predicted by the odor identification ability. Add…
View article: Human perception of Parkinson's disease body odor in comparison to the volatile organic compounds of Parkinson's disease
Human perception of Parkinson's disease body odor in comparison to the volatile organic compounds of Parkinson's disease Open
Overall, this study confirmed a distinctive body odor quality of patients with PD, which can be perceived by young women. However, the four VOCs, composing the artificial PD body odor, were insufficient to reproduce the body odor from PD p…
View article: Olfactory perceptual fingerprints of people with olfactory dysfunction and healthy controls
Olfactory perceptual fingerprints of people with olfactory dysfunction and healthy controls Open
Objective(s) An olfactory perceptual fingerprint (OPF) defines one's olfactory perception using perceptual descriptor ratings (such as odor pleasantness, intensity) for a set of odors. OPFs have been shown to distinguish patients with COVI…
View article: A practical test for retronasal odor identification based on aromatized tablets
A practical test for retronasal odor identification based on aromatized tablets Open
ThreeT is suitable for integration into scientific research and clinical practice to monitor retronasal odor identification abilities.
View article: Position paper on olfactory dysfunction: 2023
Position paper on olfactory dysfunction: 2023 Open
Background: Since publication of the original Position Paper on Olfactory Dysfunction in 2017 (PPOD-17), the personal and so- cietal burden of olfactory disorders has come sharply into focus through the lens of the COVID-19 pandemic. Clini…
View article: Impact of a 12-week olfactory training programme in women with migraine with aura: protocol for a double-blind, randomised, placebo-controlled trial
Impact of a 12-week olfactory training programme in women with migraine with aura: protocol for a double-blind, randomised, placebo-controlled trial Open
Introduction Migraine is a leading cause of disability and suffering worldwide. However, conventional pharmacological migraine preventive therapies are often challenging and accompanied by adverse effects. Recently, structured odour exposu…
View article: Depression Severity Is Different in Dysosmic Patients Who Have Experienced Traumatic Brain Injury Compared with Those Who Have Not
Depression Severity Is Different in Dysosmic Patients Who Have Experienced Traumatic Brain Injury Compared with Those Who Have Not Open
Traumatic brain injury (TBI) in humans can result in olfactory, cognitive, and affective changes. Surprisingly, research on the consequences of TBI often did not control for olfactory function in the investigated groups. Consequently, the …
View article: Diagnosed and subjectively perceived long-term effects of COVID-19 infection on olfactory function assessed by supervised machine learning
Diagnosed and subjectively perceived long-term effects of COVID-19 infection on olfactory function assessed by supervised machine learning Open
Background Loss of olfactory function appears to be a typical COVID-19 symptom, at least in early variants of SARS-CoV2. The time that has elapsed since the emergence of COVID-19 now allows us to assess the long-term prognosis of its olfac…
View article: Olfactory training reduces pain sensitivity in children and adolescents with primary headaches
Olfactory training reduces pain sensitivity in children and adolescents with primary headaches Open
Objective Headache prevalence among children and adolescents has increased over the last few years. Evidence-based treatment options for pediatric headaches remain limited. Research suggests a positive influence of odors on pain and mood. …
View article: Topical Administration of Mometasone Is Not Helpful in Post-COVID-19 Olfactory Dysfunction
Topical Administration of Mometasone Is Not Helpful in Post-COVID-19 Olfactory Dysfunction Open
Persistent olfactory dysfunction is a major concern post-COVID-19, affecting up to 5% of all patients. Different therapeutic options, including mometasone nasal spray, have been recommended, only some of which have been validated for post-…
View article: Migraine type-dependent patterns of brain activation after facial and intranasal trigeminal stimulation
Migraine type-dependent patterns of brain activation after facial and intranasal trigeminal stimulation Open
In migraine, the trigeminal nerve is intimately involved in the pathophysiology of the disease. We hypothesized that alterations in the sensory trigeminal activation in migraine would be reflected by EEG-derived event-related potentials (E…
View article: Impact of COVID-19-Mediated Olfactory Loss on Quality of Life
Impact of COVID-19-Mediated Olfactory Loss on Quality of Life Open
Introduction: COVID-19 can be associated with a variety of longer-lasting impairments that can have a significant impact on patients’ quality of life (QoL). While this is well described in the literature for limitations in lung capacity or…
View article: Symptoms of depression change with olfactory function
Symptoms of depression change with olfactory function Open
Olfactory loss is associated with symptoms of depression. The present study, conducted on a large cohort of mostly dysosmic patients, aimed to investigate whether improvement in olfactory performance would correspond with a decrease in dep…